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Ho, Tiffany; Guidolin, Keegan; Makky, Ali; Valic, Michael; Ding, Lili; Bu, Jiachuan; Zheng, Mark; Cheng, Miffy H. Y.; Yau, Jeremy; Chen, Juan; Zheng, Gang
Angewandte Chemie International Edition, April 11, 2023, 2023-04-11, Volume: 62, Issue: 16Journal Article
The superior efficacy of aminopolycarboxylic acid conjugated lipid nanoparticles over standard liposomal nanoparticles is described by Juan Chen, Gang Zheng et al. in their Research Article (e202218218). EDTA–lipid based nanoparticles fluidize the cell membrane in a detergent‐like manner and improve delivery to the cell by 25‐fold. This novel nanoparticle design feature can be deployed across lipid nanoparticles to accelerate cancer nanomedicine drug delivery.
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