Organizational climate is a concept that has attracted considerable attention from practitioners and academics alike. However, recent developments in the B2B space, including the emergence of complex and dynamic environments, the expansion in the number and types of parties involved in B2B exchanges, and changes in the work environment, require a better understanding of the role of organizational climate. To synthesize B2B knowledge associated with organizational climates, we undertook a systematic review. Our results point toward six organizational climate dimensions, which have at their core issues related to Human Resources, Service, Interpersonal Relationships, Coordination, Environmental, and Exploration. Among these, the Exploration dimension is specific to B2B. Building from these dimensions, we highlight emerging research streams focused on interactions and relationships. We contribute to the literature on B2B organizational climate by bringing clarity and a research agenda for central topics that require further attention. •Organizational climate reflects perceptions related to the workplace in the increasingly complex and competitive B2B space•There are six main themes of research in B2B organizational climate, corresponding to six B2B climate dimensions: human resources, service, interpersonal relationships, coordination, environmental, and exploration.•There is an emphasis on ethical, psychological and innovation climate, at the expense of other types of focused climates•For B2B organizations, the nature and the type of interactions that take place between parties are evolving and become more complex•Avenues for future research delineate how organizational climate can be employed in B2B relationships