GENETIC TARGET VALIDATION FOR ATP-CITRATE LYASE INHIBITION

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GENETIC TARGET VALIDATION FOR ATP-CITRATE LYASE INHIBITION

Ference, Brian A; Neff, David; Cabot, Martin; Catapano, Alberico; Ray, Kausik

Journal of the American College of Cardiology, 03/2017, Volume: 69, Issue: 11

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Background: Bempedoic acid is a novel oral agent that reduces hepatic cholesterol synthesis by inhibiting ATP-citrate lyase (ACL) leading to upregulation of the LDL receptor and a reduction in plasma low-density lipoprotein cholesterol (LDL-C).

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Ference, Brian A | Neff, David | Cabot, Martin | Catapano, Alberico | Ray, Kausik

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Year	Impact factor		Edition		Category		Classification
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