We study the microstructure, optical, thermal, dielectric, and mechanical properties of flexible oxidized cellulose (OC) films loaded with different mass fractions of cubic structure Bi0.5Na0.25K0.25TiO3 by blending solution technique and casting method. The films were characterized using infrared, X-ray diffraction, scanning electron microscopy, and UV–visible spectroscopy. The optical results confirmed the formation of crystalline bismuth sodium titanate/OC semiconductor films with a direct energy bandgap (3.002–3.276 eV) and have the ability for optoelectronic applications. The dielectric constant and dielectric loss of OC /BNKT film decreased obviously with increasing frequency. However, the ferroelectric state of the BNKT and its correlation with structure verified the existence of a relaxer behavior to this ratio. OC film with 20% dopped BNKT displayed energetic bactericidal activity against Gram-positive and Gram-negative bacteria. The presented study suggested that this film can be used as an antibacterial packaging material to diminish packaging's adverse environmental impacts with non-cytotoxicity. Display omitted