A surface layered structure of the Al0.5CoCrFeNiSi0.25 high-entropy alloys was prepared via laser remelting (LR). The microstructures were characterized via optical microscopy, scanning electron microscopy, and electron backscatter diffraction techniques. The microhardness and wear properties of the LR alloys were evaluated in comparison with the as-cast alloy. The results showed that the microstructure of the surface layers can be tailored by changing laser scanning speed. With increasing the laser scanning speed from 3 mm/s to 7 mm/s, the thickness of the molten pool gradually decreased. Meanwhile, the microstructure of the layers changed from BCC + FCC dual-phase layers to BCC phase layers (BCC + B2 phase). And the thickness of BCC + FCC dual-phase layers gradually decreased. When the laser scanning speed reached 7 mm/s, the microstructure of the surface layer was only the BCC phase and the hardness of the BCC layer was doubled compared with the as-cast alloy, which also resulted in a sequential increase in scratch resistance. The relatively high hardness of the layered structure also led to its macroscopic wear resistance higher than that of the as-cast alloy, and the wear mechanism was mainly abrasive wear. •A layered structure with difference microstructure can be tailored by changing laser scanning speed.•The BCC phase layer is achieved with high laser scanning speed of 7 mm/s and its hardness is doubled than the as-cast alloy.•The hardness and wear resistance is enhanced after remelting.