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Kurihara, Masanori; Bannai, Taro; Otsuka, Juuri; Kawabe Matsukawa, Miho; Terao, Yasuo; Shimizu, Jun; Tsuji, Shoji
Clinical neurology and neurosurgery, October 2018, 2018-10-00, 20181001, Volume: 173Journal Article
•Optic neuropathy and decorticate-like posture can be seen in Bickerstaff’s brainstem encephalitis.•Decorticate-like posture does not necessarily indicate poor prognosis.•Early diagnosis is necessary for adequate management. A 72-year-old woman with a 10-day history of bilateral visual impairment after respiratory tract infection showed decorticate-like posture and progressive deterioration of consciousness leading to coma. Ophthalmoplegia was also noted and anti-GQ1b antibodies were positive, consistent with Bickerstaff’s brainstem encephalitis. After intravenous immunoglobulin and steroid pulse therapy, her consciousness gradually improved. However, severe visual impairment at the level of hand motion was noticed, which gradually normalized after second steroid pulse therapy. Atypical findings including optic neuropathy and decorticate-like posture can be seen in patients with Bickerstaff’s brainstem encephalitis, and early diagnosis is essential for adequate management.
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