Dye-Loaded Ferritin Nanocages for Multimodal Imaging and Photothermal Therapy

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Dye-Loaded Ferritin Nanocages for Multimodal Imaging and Photothermal Therapy

Huang, Peng; Rong, Pengfei; Jin, Albert; Yan, Xuefeng; Zhang, Molly Gu; Lin, Jing; Hu, Hao; Wang, Zhe; Yue, Xuyi; Li, Wanwan; Niu, Gang; Zeng, Wenbin; Wang, Wei; Zhou, Kechao; Chen, Xiaoyuan

Advanced materials (Weinheim), 10/2014, Volume: 26, Issue: 37

Journal Article

Multimodal imaging‐guided photothermal therapy (PTT), for the therapy of cancer, based on a ferritin (FRT) nanocage loaded with the near‐infrared dye IR820 (designated DFRT) is demonstrated. The dual roles of DFRT (in imaging and PTT) are successfully balanced by using two different excitation wavelengths: 550 nm for high quantum‐yield fluorescence imaging on the one hand and 808 nm for photoacoustic imaging and PTT with high photothermal conversion efficiency on the other.

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