...it is noteworthy that the antioxidants play a crucial role in both food systems and in the human body to reduce oxidative processes and, consequently, neurodegenerative diseases and metabolic dysfunctions. According to these authors, E. oleracea can improve GABAergic neurotransmission via interactions with the GABAA receptor and modulation of GABA uptake, possibly leading to the accumulation of endogenous GABA in the synaptic cleft and enhancing the inhibitory neurotransmission in the brain. ...the Guest Editors are very grateful to the authors who submitted their precious research to this special issue, and they would also like to warmly acknowledge the reviewers for their excellent contribution to improve the quality of this work.