E-resources
Peer reviewed
Open access
-
Suneja, Gita; Lin, Chun Chieh; Simard, Edgar P.; Han, Xuesong; Engels, Eric A.; Jemal, Ahmedin
Cancer, August 1, 2016, 2016-08-01, 2016-08-00, 20160801, Volume: 122, Issue: 15Journal Article
BACKGROUND Patients with cancer who are infected with the human immunodeficiency virus (HIV) are less likely to receive cancer treatment compared with HIV‐uninfected individuals. However, to the authors' knowledge, the impact of insurance status and comorbidities is unknown. METHODS Data from the National Cancer Data Base were used to study nonelderly adults diagnosed with several common cancers from 2003 to 2011. Cancer treatment was defined as chemotherapy, surgery, radiotherapy, or any combination during the first course of treatment. Multivariate logistic regression was used to examine associations between HIV status and lack of cancer treatment, and identify predictors for lack of treatment among HIV‐infected patients. RESULTS A total of 10,265 HIV‐infected and 2,219,232 HIV‐uninfected cases were included. In multivariate analysis, HIV‐infected patients with cancer were found to be more likely to lack cancer treatment for cancers of the head and neck (adjusted odds ratio aOR, 1.48; 95% confidence interval 95% CI, 1.09‐2.01), upper gastrointestinal tract (aOR, 2.62; 95% CI, 2.04‐3.37), colorectum (aOR, 1.70; 95% CI, 1.17‐2.48), lung (aOR, 2.46; 95% CI, 2.19‐2.76), breast (aOR, 2.14; 95% CI, 1.16‐3.98), cervix (aOR, 2.81; 95% CI, 1.77‐4.45), prostate (aOR, 2.16; 95% CI, 1.69‐2.76), Hodgkin lymphoma (aOR, 1.92; 95% CI, 1.66‐2.22), and diffuse large B‐cell lymphoma (aOR, 1.82; 95% CI, 1.65‐2.00). Predictors of a lack of cancer treatment among HIV‐infected individuals varied by tumor type (solid tumor vs lymphoma), but black race and a lack of private insurance were found to be predictors for both groups. CONCLUSIONS In the United States, HIV‐infected patients with cancer appear to be less likely to receive cancer treatment regardless of insurance and comorbidities. To the authors' knowledge, the current study is the largest study of cancer treatment in HIV‐infected patients with cancer in the United States and provides evidence of cancer treatment disparities even after controlling for differences with regard to insurance status and comorbidities. Further work should focus on addressing differential cancer treatment. Cancer 2016;122:2399–2407. © 2016 American Cancer Society. Human immunodeficiency virus (HIV)‐infected patients with cancer in the United States are less likely to receive cancer treatment compared with their uninfected counterparts, even after factoring in differences in insurance status and medical comorbidities. This disparity needs to be addressed as survival from HIV continues to improve and cancer becomes one of the leading causes of death in the HIV population.
Author
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
The material is available in full text. If you wish to order the material anyway, click the Continue button.