We compared three types of resilience (individual, community, and national resilience), two indicators of distress (sense of danger and distress symptoms) and wellbeing, among samples from Israel, Brazil, and the Philippines, during the “first-wave” of COVID-19 pandemic. Though significant differences were found among the samples regarding all variables, similarities were also emerged. Individual resilience and wellbeing negatively predicted distress symptoms in each sample, and women of all samples reported higher level of distress-symptoms compared with men. The differences between the samples are presented and discussed. Understanding the similarities and the differences, between these cultures, may help developing efficient countermeasures tailored to each country. This knowledge may promote efficient health policy to foster people’s ability to cope with the hardship and to prevent future psychological and health implications.