Formaldehyde (FA) is a chemical compound commonly used in anatomical pathology laboratories as a tissue preservative, and it is common and epidemiologically related to cancer. Therefore, the personnel resident in the anatomical pathology laboratories is among the workers most exposed to FA and its related cancer and non-cancerogenic risk. Thus, risk assessment, cancerogenic and non-cancerogenic, and a careful occupational exposure assessment are recommended. In this study, FA was monitored in an Italian anatomical pathology laboratory to perform an occupational exposure assessment, according to the UNI EN 689:219, and to determine the Hazard Quotient (HQ) and the Lifetime Cancer Hazard Risk (LCHR) for carcinogenic and non-carcinogenic risk assessment, respectively. The exposure observed for pathologists and technicians is lower than the EU Occupational exposure limit mandatory (0.62 mg/m3), and both group of workers are in Compliance with it. Nevertheless, concerning the risk assessment, both the HQs and the LCHRs resulted in being higher (1.3 and 1.6 HQ and 3.2x10-5 and 3.9x10-5, for pathologists and technicians, respectively) than the ones observed in similar scenarios. This study shows how the exposure assessment to FA could face striving situations in terms of workers' health safeguard, due to the differences among occupational limits recommended and the high health risks, especially in the healthcare field. Formaldehid je kemijski spoj koji se obično koristi u laboratorijima za anatomsku patologiju kao konzervans za čuvanje tkiva, a često ga se povezuje s rakom. Osoblje u takvim laboratorijima najizloženije je formaldehidu i s njim povezanom raku, a i nekancerogenom riziku. Stoga se preporuča procjena rizika, kancerogenih i nekancerogenih, a također i procjena izloženosti na radu. Ova studija pratila je formaldehid u jednom talijanskom laboratoriju za patologiju kako bi se procijenila izloženost na radu prema UNI EN 689:219 i utvrdio kvocijent opasnosti (HQ) kao i doživotnog rizika od raka (LCHR) te kancerogeni i nekancerogeni rizici. Izloženost patologa i tehničara bila je niža od Europske obvezne granice za izloženost na radu (0.62 mg/m3) i obje skupine bile su ispod te granice. No, ipak, što se tiče procjene rizika, oba parametra HQ i LCHR bila su viša (1.3 i 1.6 HQ, i 3.2x10-5 i 3.9x10-5 za patologe te tehničare, tj. viša od drugih zamijećenih u sličnim situacijama. Studija prikazuje kako procjena izloženosti formaldehidu može pomoći u očuvanju zdravlja radnika utvrđivanjem odstupanja od preporučenih graničnih vrijednosti i posljedično visokih rizika za zdravlje, posebno u zdravstvu.