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  • SeXX Matters in Infectious ...
    vom Steeg, Landon G; Klein, Sabra L

    PLoS pathogens, 02/2016, Volume: 12, Issue: 2
    Journal Article

      A future challenge will be to interpret immunological differences between the sexes in the context of infectious disease pathogenesis.\n The binding of sex steroids to their respective steroid receptors directly influences signaling pathways associated with the production of cytokines and chemokines 22. Interpretation of sex differences in the expression of X-linked genes is challenging because sex hormones or sex chromosome complement can still contribute to the observed differential gene expression.