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  • Naše izkušnje zdravljenja z interferonom alfa pri mlajših bolnikih z esencialno trombocitemijo = Our experience with interferon alpha therapy in younger patients with essential thrombocytaemia
    Glaser, Marjana
    Background. Essential thombocytemia (ET) is a chronic myeloproliferative disease with megakaryocyte cell line proliferation in bone marrow and excessive overproduction of morphologically and ... functionally abnormal platelets in blood. Two thirds of patients are symptomatic with various symptoms, which are of bleefing and thrombosis origin and can lead ro death. Current therapy is focused on prevention of this complications and several therapeutic agents are capable to lower the planet count in this patients. Patients and methods. We present 5 younger patients with different difficulties. As the only reason, ET was established and induction therapy with interferon alpha (IFN) was started and later continued as intermittent therapy from 4 till 8 years. Conclusions. IFN has been shown to have a therapeutic effect in patients with ET. The treatment with IFN is recommended especially in young people to avoid treatment with cytotoxic agents.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 69, št. 1, jan. 2000, str. 11-13)
    Vrsta gradiva - članek, sestavni del
    Leto - 2000
    Jezik - slovenski
    COBISS.SI-ID - 11137497

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