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  • Diagnostika pomanjkanja vitamina B12 in folatov = Diagnosis of vitamin B12 and folate deficiency
    Mlakar, Uroš, 1948-
    The evaluation of suspected cobalamin (vitamin B12) or folate deficiency generally proceeds in three stages:1) recognizing that megaloblastic anaemia is present, 2) documenting the presence of ... cobalamin or folate deficiency and 3) determining its cause. The megaloblasic anaemia is established by evaluating the complete blood count and blood smear with characteristic macroovalocytes and hypersegmented neutrophils. Bone marrow examination is usually unnecessary. Answer whether cobalamin or folate deficiency is responsible for megaloblastic anaemia can be obtained by serum cobalamin and serum folate levels. Additional testing of serum methylmalonic acid and total serum homocysteine is recommended for interpreting borderline cobalamin and folate levels, to rule out cobalamin deficiency when both cobalamin and folatelevels are low, and in conditions known to perturb cobalamin and folate tests. In most cases the last step in evaluation of cobalamin and folate deficiency involves identifying pernicious anaemia by evaluation of cobalamin absorption with Schilling test.
    Vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 39, supl. 7, okt. 2000, str. 41-45)
    Vrsta gradiva - članek, sestavni del
    Leto - 2000
    Jezik - slovenski
    COBISS.SI-ID - 12356825

vir: Medicinski razgledi. Supplement. - ISSN 0353-3484 (Letn. 39, supl. 7, okt. 2000, str. 41-45)

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