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  • Invazivna aspergiloza pljuč pri bolnici s sarkoidozo : primer iz klinične prakse = Invasive lung aspergillosis in patient with sarcoidosis : case report
    Škrgat, Sabina ; Kern, Izidor ; Debeljak, Andrej, 1940-
    Background. Invasive lung aspergillosis usually affects severely immunocompromised hosts. We present a 71 years old woman with sarcoidosis stadium III who had been taking methylprednisolne 24 mg ... daily in tapered dosesfor five months. In this period of time she was successfully treated for pulmonary embolism. She had been taking 16 mg of methylprednisolone in her last six weeks of life. At admission she was comatose. She had soor in her month and in the surface of genitalia. The value of PaO2 on 35% venti mask was8.9 kPa. Chest X-ray showed bilateral interstinal and alveolar infiltrates with thickened pleura and plaural effusion. The number of white blood cells was 11.2 x 10/L, number of platelets 60 x 10/L, laboratory liver tests were pathologic. Haemocultures were sterile. The pharinx smear for Mycobacterium tuberculosis was negative. The patient was treated for active tuberculosis. Invasive diagnostic procedure was not possible because of hypoxaemia and thrombocytopenia. She died 48 hours after the admission. Disseminated infection with Aspergillus fumigatus with extensive invasive lung aspergillosis was found at autopsy. Conclusions. Invasive lung aspergillosis must be also considered in patient with minimal immunosuppression and pulmonary infiltrates. Patients treated with low doses of corticosteroids because of pulmonary diseases also belong to this group.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 70, št. 1, jan. 2001, str. 13-15)
    Vrsta gradiva - članek, sestavni del
    Leto - 2001
    Jezik - slovenski
    COBISS.SI-ID - 12788441

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