NUK - logo
Narodna in univerzitetna knjižnica, Ljubljana (NUK)
Naročanje gradiva za izposojo na dom
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi
  • Spremembe števila in prostornine trombocitov pri idiopatični trombocitopenični purpuri = Platelet number and volume changes in idiopathic thrombocytopenic purpura
    Tomažič, Mojca ; Andoljšek, Dušan
    Background. Mean platelet volume (MPV) is increased in stress thrombopoesis. Conditions for platelet production in idiopathic thrombocytopenic purpura (ITP) are changed and the same is true after ... treatment. These possibly could have influence on MPV. If we belive the hypothesis that platelet production isregulated to maintain a constant circulating platelet mass, there could be the correlation between platelet number and MPV in ITP. Methods. 29 healthy blood donors and 73 patients with ITP were examined. Blood samples with K-EDTAwere analysed by cell counter Coulter STKS System for platelet number and MPV. Analyses were done one hour after venepuncture. Results. There are statistically significant differences for MPV in ITP patients and controls. Differences are more pronounced after splenectomy and less in patients groups with no treatment or with corticosteroids. There is a negative correlation between platelet number and MPV in controls and splenectomy group of patients.No correlation was found in patient group with no treatment or with corticosteroids. Conclusions. MPV is increased in ITP. There is a significant negative correlation between platelet number and MPV in controls and splenectomy group of patients. No correlation was found for platelet number and MPV in corticosteroids and no treatement grou of patients. Platelet pool in the spleen, which can not be assesed, probably influence the data for thesepatient groups. If we consider the hypothesis that platelet production isregulated to maintatin a constant circulating platelet mass, than such a mechanism is operating in ITP after splenectomy.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 67, supl. 1, maj 1998, str. I-73-I-76)
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - slovenski
    COBISS.SI-ID - 7944921

Vnos na polico