Corporate volunteering programs are important channels for expressing care and compassion, but little research has examined when and why employees sustain involvement. Integrating work design and ...volunteering theories, I introduce a model that explains how depleted task, social, and knowledge characteristics of jobs trigger compensatory motives during initial volunteering episodes. When these motives are fulfilled by volunteering projects, employees repeat participation, internalizing volunteer identities—contingent on pressure, matching incentives, recognition, managerial support, and targeted causes.
Human social networks are overwhelmingly homophilous: individuals tend to befriend others who are similar to them in terms of a range of physical attributes (e.g., age, gender). Do similarities among ...friends reflect deeper similarities in how we perceive, interpret, and respond to the world? To test whether friendship, and more generally, social network proximity, is associated with increased similarity of real-time mental responding, we used functional magnetic resonance imaging to scan subjects' brains during free viewing of naturalistic movies. Here we show evidence for neural homophily: neural responses when viewing audiovisual movies are exceptionally similar among friends, and that similarity decreases with increasing distance in a real-world social network. These results suggest that we are exceptionally similar to our friends in how we perceive and respond to the world around us, which has implications for interpersonal influence and attraction.
The COVID-19 pandemic has been a life threatening and spreads wildly with physical human contact. Physical distancing is recommended by health experts to prevent the spread; thus, agronomic research ...has to be designed in conformity to this preventive standard during the pandemic. Consequently, this study was designed to evaluate the reliability of using digital tools in nutrient management research amid the COVID-19 pandemic in northern Nigeria. Fifty extension agents (EAs) were selected across 15 LGAs of Kaduna and Kano states. The EAs were trained on how to generate fertilizer recommendation using an android mobile phone-based nutrient expert (NE), to measure farmers' field sizes using UTM Area measure mobile phone app, and open data kit to record, submit and aggregate data during the exercise. Each EA covered 50 farms, where two nutrient management practices-one determined by the farmers: farmer fertilizer practice (FFP), and the other generated using the NE were evaluated. Results show that around 90% of the farmers have an average field size of 1.13 ha. All selected farmers used improved maize varieties for planting, among which 21% been able to use the exact recommended or lower seed rate. Use of inorganic fertilizer was 33% higher than the average recommended NE rate, while average yield of the NE fields was 48% higher than for the FFP. The results of this study indicate that yield can be improved with site-specific nutrient management (SSNM) extension approach. The SSNM using digital tools as the NE seem promising and befits to agronomic research in northern Nigeria amid the COVID-19 pandemic.
Antiretroviral therapy (ART) has rendered HIV-1 infection a treatable illness; however, ART is not curative owing to the persistence of replication-competent, latent proviruses in long-lived resting ...T cells. Strategies that target these latently infected cells and allow immune recognition and clearance of this reservoir will be necessary to eradicate HIV-1 in infected individuals. This review describes current pharmacologic approaches to reactivate the latent reservoir so that infected cells can be recognized and targeted, with the ultimate goal of achieving an HIV-1 cure.
Intense emotions such as frustration, anger, and dissatisfaction often drive employees to speak up. Yet the very emotions that spur employees to express voice may compromise their ability to do so ...constructively, preventing managers from reacting favorably. I propose that to speak up frequently and constructively, employees need knowledge about effective strategies for managing emotions. Building on theories of emotion regulation, I develop a theoretical model that explains the role of managing emotions in the incidence and outcomes of voice. In a field study at a health care company, emotion regulation knowledge (1) predicted more frequent voice, (2) mediated by the emotional labor strategies of deep acting and surface acting, and (3) enhanced the contributions of voice to performance evaluations. These results did not generalize to helping behaviors, demonstrating that emotion regulation uniquely affects challenging but not affiliative interpersonal citizenship behaviors. This research introduces emotion regulation as a novel influence on voice and its consequences.
Nationally representative studies confirm that LGBTQ individuals are at an elevated risk of experiencing intimate partner violence. While many similarities exist between LGBTQ and ...heterosexual-cisgender intimate partner violence, research has illuminated a variety of unique aspects of LGBTQ intimate partner violence regarding the predictors of perpetration, the specific forms of abuse experienced, barriers to help-seeking for victims, and policy and intervention needs. This is the first book that systematically reviews the literature regarding LGBTQ intimate partner violence, draws key lessons for current practice and policy, and recommends research areas and enhanced methodologies.
Genome-wide cancer mutation analyses are revealing an extensive landscape of functional mutations within the noncoding genome, with profound effects on the expression of long noncoding RNAs ...(lncRNAs). While the exquisite regulation of lncRNA transcription can provide signals of malignant transformation, we now understand that lncRNAs drive many important cancer phenotypes through their interactions with other cellular macromolecules including DNA, protein, and RNA. Recent advancements in surveying lncRNA molecular mechanisms are now providing the tools to functionally annotate these cancer-associated transcripts, making these molecules attractive targets for therapeutic intervention in the fight against cancer.
Genome-wide cancer mutation analyses are revealing an extensive landscape of functional mutations within the noncoding genome, with profound effects on the expression of long noncoding RNAs (lncRNAs). While the exquisite regulation of lncRNA transcription can provide signals of malignant transformation, we now understand that lncRNAs drive many important cancer phenotypes through their interactions with other cellular macromolecules including DNA, protein, and RNA. Recent advancements in surveying lncRNA molecular mechanisms are now providing the tools to functionally annotate these cancer-associated transcripts, making these molecules attractive targets for therapeutic intervention in the fight against cancer.
Abstract We present an analysis of high-resolution far-UV archival spectra obtained with the Space Telescope Imaging Spectrograph on the Hubble Space Telescope of the star HD 75309, which probes ...high-velocity shocked gas in the Vela supernova remnant (SNR). We examine high-velocity features from intrinsically strong absorption lines of O i , Si ii , Si ii *, C ii , C ii *, and Si iii . We also detect high-velocity components in the N v doublet and compare these features to observations of high-velocity O vi absorption, available from archival Far Ultraviolet Spectroscopic Explorer data. Kinetic temperatures are derived from the observed fractional abundances of the various ions, while gas densities and thermal pressures are obtained from the relative populations in excited fine-structure levels of C ii and Si ii . Our results indicate that the highly ionized species at high velocity probe gas in a region immediately behind a shock driven into an interstellar cloud, while the lower-ionization species trace material further downstream in the cooling region of the postshock flow. Low-velocity N v and O vi absorption may trace gas in a conductive boundary layer between the unshocked portion of the cloud and the hot X-ray-emitting intercloud medium. Temporal variations in high-velocity Ca ii absorption features observed toward HD 75309 further confirm the highly inhomogeneous nature of the interstellar medium interacting with the Vela SNR.
A fundamental question in microbiology is whether there is continuum of genetic diversity among genomes, or clear species boundaries prevail instead. Whole-genome similarity metrics such as Average ...Nucleotide Identity (ANI) help address this question by facilitating high resolution taxonomic analysis of thousands of genomes from diverse phylogenetic lineages. To scale to available genomes and beyond, we present FastANI, a new method to estimate ANI using alignment-free approximate sequence mapping. FastANI is accurate for both finished and draft genomes, and is up to three orders of magnitude faster compared to alignment-based approaches. We leverage FastANI to compute pairwise ANI values among all prokaryotic genomes available in the NCBI database. Our results reveal clear genetic discontinuity, with 99.8% of the total 8 billion genome pairs analyzed conforming to >95% intra-species and <83% inter-species ANI values. This discontinuity is manifested with or without the most frequently sequenced species, and is robust to historic additions in the genome databases.
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