This paper presents a systematic literature review, providing a comprehensive taxonomy of Data Augmentation (DA), Transfer Learning (TL), and Self-Supervised Learning (SSL) techniques within the ...context of Few-Shot Learning (FSL) for EEG signal classification. EEG signals have shown significant potential in various paradigms, including Motor Imagery, Emotion Recognition, Visual Evoked Potentials, Steady-State Visually Evoked Potentials, Rapid Serial Visual Presentation, Event-Related Potentials, and Mental Workload. However, challenges such as limited labeled data, noise, and inter/intra-subject variability have impeded the effectiveness of traditional machine learning (ML) and deep learning (DL) models. This review methodically explores how FSL approaches, incorporating DA, TL, and SSL, can address these challenges and enhance classification performance in specific EEG paradigms. It also delves into the open research challenges related to these techniques in EEG signal classification. Specifically, the review examines the identification of DA strategies tailored to various EEG paradigms, the creation of TL architectures for efficient knowledge transfer, and the formulation of SSL methods for unsupervised representation learning from EEG data. Addressing these challenges is crucial for enhancing the efficacy and robustness of FSL-based EEG signal classification. By presenting a structured taxonomy of FSL techniques and discussing the associated research challenges, this systematic review offers valuable insights for future investigations in EEG signal classification. The findings aim to guide and inspire researchers, promoting advancements in applying FSL methodologies for improved EEG signal analysis and classification in real-world settings.
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•This review provides a comprehensive study of biosensors and covers almost all the relevant topics, including components, working, and parameters.•The review covers a wide range of ...biosensors and highlights their applications in various fields like security, drug development, and agriculture.•The review briefly elaborates the mechanism of each biosensor's different phenomena to better understand the reader.•This review discusses the timeline of biosensors from their origin to the prospects and gives an insight into all of the major events.•This review focuses on the present trends in biosensors in IoT, Telecommunications, COVID 19 rapid detection kits.
Crucial exploitation of biosensors has attained dominant significance in the meadow of drug innovation, drug identification, bio-remedy, food protection principles, security, protection, and ecological examination. It has direct to the innovation of specific and authoritative diagnostic tools that employ biological sensing elements as biosensors. Glucometers employ oxygen or hydrogen peroxide electrochemical recognition utilizing immobilized glucose oxidase electrodes, showing biosensors' invention. Current advances in biological methods and instrumentation relating to fluorescence tags to nano-materials have increased the responsive limit of biosensors. The use of aptamers or nucleotides, antibodies, peptide arrays, and molecule imprinted polymers offer tools to build up novel biosensors over the classical method. Integrated methods offer an improved perception for a buildup of precise and responsive biosensors with high regenerative potentials. Various biosensors ranging from nanomaterials polymers to microbes have more comprehensive potential applications. Combining multifaceted approaches to design biosensors that comprise the prospective for different usage is reasonably significant. In light of this, this review provides an overview of different types of biosensors being used, ranging from electrochemical and fluorescence tagged, nanomaterials, silica or quartz, and microbes for various biomedical and environmental applications with the future outlook of biosensor technology.
Accurate lesion targeting is the essence of stereotactic radiosurgery. With the currently available imaging modalities, scanning has become quick and robust providing a high degree of spatial ...resolution resulting in optimal contrast between normal and abnormal tissues. Magnetic resonance imaging (MRI) forms the backbone of Leksell radiosurgery. It produces images with excellent soft tissue details highlighting the target and surrounding "at-risk" structures conspicuously. However, one must be aware of the MRI distortions that may arise during treatment. Computed tomography (CT) has quick acquisition times giving excellent bony information but inferior soft tissue details. To avail benefits of both these modalities and overcome their individual fallacies and shortcomings, they are often co-registered/fused for stereotactic guidance. Vascular lesions like an arteriovenous malformation (AVM) are best planned with cerebral digital subtraction angiography (DSA) in conjunction with MRI. In specific cases, specialized imaging methods like magnetic resonance (MR) spectroscopy, positron emission tomography (PET), magneto-encephalography (MEG), etc., may be added to the treatment planning for stereotactic radiosurgery (SRS).
Background and objectives
Injection and inhalational heroin use are associated with different levels of brain exposure to heroin and its metabolites and differences in the severity of dependence, ...which might lead to differential impacts on neuropsychological functions. We examined the difference and the magnitude of difference in the neuropsychological functions between inhalational and injection heroin-dependent subjects and also compared them with healthy controls.
Methods
The study sample comprised three groups: 73 subjects with injection heroin dependence, 74 with inhalational heroin dependence, and 75 healthy controls (HC). We excluded patients with HIV, head injury, epilepsy, and severe mental illness. Neuropsychological assessments were done by Standard Progressive Matrices, Wisconsin Card Sorting Test (WCST), Iowa Gambling Task, Trail-Making Tests A and B (TMT), and Verbal and Visual Memory 1 and 2 Backtests (NBT). We estimated independent effects of the groups on various neuropsychological test parameters, adjusted for age and duration of dependence.
Results
In the WCST, the inhalational heroin-dependent group took more trials to complete the first category and had higher scores in the failure to maintain set than controls. The intravenous group had higher total errors than controls in verbal working memory tests and Visual Working Memory 2 Backtest. This group scored higher commission errors in the Verbal 2 Backtest than the controls. The two groups of heroin users differed in failure to maintain set and Verbal Working Memory 2 Backtests. The effect sizes of the group differences were modest.
Conclusion and scientific significance
Either route of heroin use is associated with cognitive impairments; inhalational and injection use involve different cognitive domains.
Tetraventricular Hydrocephalus (TetHCP) is a heterogeneous group of cerebrospinal fluid (CSF) flow disorders having varying success rates with Endoscopic third ventriculostomy (ETV). This is report ...on the efficacy and rationale of ETV in a specific subset of primary TetHCP with aqueductal CSF flow voids.
Patients of primary acquired TetHCP presenting with increasing head size and/or headache having aqueductal CSF flow void on sagittal Magnetic Resonance Imaging (MRI) were included in this study. All of them underwent ETV. All patients were evaluated for clinical improvement & MRI at 3 months, and need for any additional procedure, in contrast to those without CSF flow void. The pathophysiology of hyperdynamic CSF circulation and its correlation to ETV was further reviewed.
Eleven patients had tetraventricular hydrocephalus and aqueductal flow void, with age ranging from 10 months to 59 years. Two patients who could undergo quantitative flow study confirmed the hyperdynamic flow across the aqueduct. Following ETV, all showed clinical improvement. MRI at 3 months showed CSF flow void across the third ventricular stoma in addition to across the aqueduct. None of these patients required any redo procedures for a mean follow-up of 39.2 months. In contrast, there was 30% failure rate after ETV among 10 patients of tetraventricular hydrocephalus without aqueductal flow void.
Tetraventricular hydrocephalus with aqueductal CSF flow void may be a unique entity with hyperdynamic CSF circulation and relative resistance at fourth ventricular outlets. ETV is highly efficacious in these patients, resulting in consistent clinico-radiological improvement.
Medications for opioid use disorder (OUD) may influence neurocognitive functions. Inadequate power, confounders, and practice effects limit the validity of the existing research. We examined the ...change in cognitive functions in patients with OUD at 6-month buprenorphine (naloxone) posttreatment and compared the cognitive performance of the buprenorphine-treated group with control subjects.
We recruited 498 patients with OUD within a week of initiating buprenorphine. Assessments were done twice-at baseline and 6 months. Those abstinent from illicit opioids and adherent to treatment (n = 199) underwent follow-up assessments. Ninety-eight non-substance-using control subjects were recruited from the community. The neurocognitive assessments comprised the Wisconsin Card Sorting Test, Iowa Gambling Task, Trail-Making Tests A and B (TMT-A and TMT-B), and verbal and visual N-Back Test. We controlled for potential effect modifiers.
Twenty-five of the 32 test parameters significantly improved with 6 months of buprenorphine treatment; 20 parameters withstood corrections for multiple comparisons (P < 0.001). The improved test domains spread across cognitive tests: Wisconsin Card Sorting Test (perseverative errors and response, categories completed, conceptual responses), TMTs (time to complete), verbal and visual N-Back Tests (hits, omission, and total errors). After treatment, OUD (vs control subjects) had less perseverative response and error (P < 0.001) and higher conceptual response (P = 0.004) and took lesser time to complete TMT-A (P < 0.001) and TMT-B (P = 0.005). The baseline neurocognitive functions did not differ between those who retained and those who discontinued the treatment.
Cognitive functions improve in patients with OUD on buprenorphine. This improvement is unlikely to be accounted for by the practice effect, selective attrition, and potential confounders.
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