During anatomical dissection of a female Caucasian cadaver in our department we observed a combination of two rare arterial patterns of the upper limb bilaterally; a superficial ulnar artery of high ...origin in the right upper limb and some rare variations of the left axillary artery: Right arm: The superficial ulnar artery originated from the second part of the axillary artery, before the origin of the subscapular artery. It proceeded superficially in the forearm. The axillary artery continued normally in the arm as brachial artery, and finally divided into the radial and the common interosseous artery. The normal ulnar artery was absent. The presence of the superficial ulnar artery is a rare variation given that its total incidence ranges from 0.67% to 9.38%, with only 0.17% to 2% originating from the axillary artery. Left arm: The second part of the axillary artery gave rise to a first common trunk (named A), lying between the two roots of the median nerve, which divided in two new common trunks (B and C). One of these gave origin to the subscapular and the posterior circumflex humeral artery while the other gave rise to the anterior circumflex humeral artery, two muscle twigs and then continued as profunda brachii artery. The incidence of anatomic variations of the major arteries of the upper extremities ranges from 11% to 24%. Nevertheless a pattern with three common trunks comprising the origin of the profunda brachii has not yet been cited in the literature.
Breast cancer is a complex disease with variability in clinical manifestation, response to current therapy, and biochemical and histological features among various subgroups. Histologic grading and ...immuno-histochemical evaluation of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER-2), and Ki-67 proliferation index play a crucial role in increasing the differential diagnostic value among various types of breast carcinoma. The aim of this study was to determine the histopathological and immuno-histochemical characteristics of breast tumors from a University Laboratory of Pathology in Greece.
The study included female patients over 18 years of age, whose histopathological and immunohistochemical reports were stored in the archives of the First Department of Pathology of National and Kapodistrian University of Athens. The study involved 197 female patients with a median age of 70 years and median tumor size of 2.6 cm.
Most tumors were located at the left breast and ductal carcinoma was the most common histologic type (35.5%). Most tumors had histologic grade 2 (106, 53.8%), and were classified as TNM stage IIA (65, 33%). Most grade 1 and 2 tumors exhibited high expression of PR, whereas most grade 3 tumors had no PR expression. Moreover, patients with triple-negative cancer presented with grades 2 and 3 at a lower percentage compared to patients without a triple-negative phenotype (p=0.001).
The study provided valuable insights into the histopathological and immuno-histochemical characteristics involved in the development and progression of breast cancer.
High bifurcation of the brachial artery seems to be a common variation, which can occur in many different forms, and some of them might be rather rare. We report an unusual case of bilateral high ...bifurcation of the brachial artery in a male cadaver. On the right arm, high origin of the ulnar artery as superficial ulnar artery was observed. The brachial artery continued and divided at the level of the elbow into radial and common interosseous artery. On the left arm, a high bifurcation of the common interosseous artery occurred, while the rest of the brachial artery continued and at the level of the elbow bifurcated into radial and superficial ulnar artery. In both arms, the common interosseous artery followed the branching pattern of the normal ulnar artery. The so formed superficial ulnar arteries gave each four common palmar digital arteries. This case is being reported for the bilaterally different variational anatomy of the upper limb arteries.
A case of polymorphous, low-grade adenocarcinoma of the palate is presented with special emphasis on the histologic and ultrastructural features of this recently described entity.