To compare laparoscopic and open closure of perforated peptic ulcer (PPU).
The study included 153 patients who underwent PPU suturing. 78 patients underwent laparoscopic closure (laparoscopic group) ...and open suturing via upper midline laparotomy was performed in 75 cases (open group). Surgery time, postoperative pain severity, time of analgesics intake, postoperative complications, hospital-stay and and cosmetic effect were compared.
Laparoscopic PPU closure may be effective and accessible in experienced endoscopic surgeon. It significantly reduces postoperative pain severity, need for analgesics, incidence of postoperative complications and provides excellent cosmetic effect. However, there is greater time of surgery compared with open intervention. There were no significant differences in hspital-stay between groups.
Laparoscopic PPU suturing can be considered a good alternative to open surgery. Further researches are needed for standardization, assessment of safety, real advantages and disadvantages of laparoscopic technique.
To analyze the outcomes of single-port laparoscopic cholecystectomy.
Early and long-term postoperative period has been analyzed in 240 patients who underwent laparoscopic cholecystectomy (LCE) ...including 120 cases of single-port technique and 120 cases of four-port technique. Both groups were compared in surgical time, pain syndrome severity (visual analog scale), need for analgesics, postoperative complications, hospital-stay, daily activity recovery and return to physical work, patients' satisfaction of surgical results and their aesthetic effect.
It was revealed that single-port LCE is associated with lower severity of postoperative pain, quick recovery of daily activity and return to physical work, high satisfaction of surgical results and their aesthetic effect compared with four-port LCE. Disadvantages of single-port LCE include longer duration of surgery, high incidence of postoperative umbilical hernia. However hernia was predominantly observed during the period of surgical technique development.
Further studies to standardize, evaluate the safety and benefits of single-port LCE are necessary.
A search for the rare two-body charmless baryonic decay $B^+ \to p \bar\Lambda$ is performed with $pp$ collision data, corresponding to an integrated luminosity of $3\mbox{\,fb}^{-1}$, collected by ...the LHCb experiment at centre-of-mass energies of 7 and 8 TeV. An excess of $B^+ \to p \bar\Lambda$ candidates with respect to background expectations is seen with a statistical significance of 4.1 standard deviations, and constitutes the first evidence for this decay. The branching fraction, measured using the $B^+ \to K^0_{\mathrm S} \pi^+$ decay for normalisation, is \begin{eqnarray} \mathcal{B}(B^+ \to p \bar\Lambda) & = & ( 2.4 \,^{+1.0}_{-0.8} \pm 0.3 ) \times 10^{-7} \,, \nonumber \end{eqnarray} where the first uncertainty is statistical and the second systematic.
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