The reduction of energy costs in the production of livestock products by maintaining the required illumination parameters is an important task. The results of studies on the development of a program ...for automatic control and maintenance of lighting parameters in premises for keeping birds, depending on the cross, technologies of keeping and the age of birds, using programmable logic controllers (PLC) are presented. The use of a dimming system will reduce the energy consumption of lighting equipment and increase the efficiency of electrical energy use.
We have studied neutron quantum states in the potential well formed by the earth’s gravitational field and a horizontal mirror. The estimated characteristic sizes of the neutron wave functions in the ...two lowest quantum states correspond to expectations with an experimental accuracy. A position-sensitive neutron detector with an extra-high spatial resolution of \(\sim 2 \mathrm{\mu} \)m was developed and tested for this particular experiment, to be used to measure the spatial density distribution in a standing neutron wave above a mirror for a set of some of the lowest quantum states. The present experiment can be used to set an upper limit for an additional short-range fundamental force. We studied methodological uncertainties as well as the feasibility of improving further the accuracy of this experiment.
•Laser method for synthesis of bimetallic materials for enzyme-free microbiosensors.•Relationship between the structure of complexes and the properties of microbiosensors is shown.•The gap in ...knowledge about the structure of bimetal wine complexes has been filled.
The use of laser methods for synthesizing new materials for non-enzymatic electrochemical microsensors for express analysis of biological fluids is a promising scientific question.
Laser-induced chemical liquid phase deposition is the laser deposition of invisible miniature bimetallic deposits from aqueous solutions of salts and complexes of transition metals. Bimetallic complexes containing two transition metal cations in the shell of one ligand are of increased interest. There is an information gap in this area even for ligands such as tartrate. The studies carried out make it possible to obtain new information on the structure of bimetallic tartaric complexes in solutions containing simultaneously copper, nickel, silver, iron, and cobalt.
Serum amyloid A protein (SAA) is an acute-phase reactant, known to mediate pro-inflammatory cellular responses. This study
reports that CLA-1 (CD36 and LIMPII Analogous-1; human orthologue of the ...Scavenger Receptor Class B Type I (SR-BI)) mediates
SAA uptake and downstream SAA signaling. Flow cytometry experiments revealed more than a 5-fold increase of Alexa-488 SAA
uptake in HeLa cells stably transfected with CLA-1. Alexa 488-HDL uptake directly correlated with SAA uptake when determined
in several CLA-1 stably transfected HeLa cell clones expressing various levels of CLA-1. SAA directly binds to CLA-1 as determined
by cross-linking and colocalization of anti-CLA-1 antibody with SAA. SAA was co-internalized with transferrin to the endocytic
recycling compartment pointing to a potential site of SAA metabolism. Alexa-488 SAA uptake in the CLA-1-overexpressing HeLa
cells, as well as in THP-1 monocyte cell line, can be efficiently blocked by unlabeled SAA, high density lipoprotein, and
other CLA-1 ligands. At the same time, markedly enhanced levels of phosphorylation of the mitogen-activated protein kinases
(MAPKs), ERK1/2, and p38, were observed in cells stably transfected with CLA-1 cells following SAA stimulation when compared
with mock transfected cells. The levels of the SAA-induced interleukin-8 (IL-8) secretion by CLA-1-overexpressing cells also
significantly exceeded (5- to 10-fold) those detected for control cells. Synthetic amphipathic peptides possessing a structural
α-helical motif inhibited SAA-induced activation of both MAPKs and IL-8 secretion in THP-1 cells. The results of this study
demonstrate for the first time that CLA-1 functions as an endocytic SAA receptor and is involved in SAA-mediated cell signaling
events associated with the immune-related and inflammatory effects of SAA.
The paper focuses on the relevant issue of legislative regulation of the rights of indigenous peoples of the Russian Arctic. The lands of the Arctic region have long been considered uninhabitable, ...and yet not for one century have they been explored and reclaimed by men. According to historical records, the Russian navigators sailed through the Arctic Ocean as early as the 11th century, and in the first half of the 16th century, a map of the Arctic Ocean seafloor was based on the drawings of Dmitry Gerasimov. By 16-17th centuries, the economic capacity of the Arctic territories was recognized both in Russia and in Western Europe. Some Arctic territories were featured in the treaties between the Muscovite state and the countries of Western Europe, which can be illustrated by the Treaty of Teusina signed with Sweden in 1595. However, the Government of the Russian Empire had long considered the development of the North as necessary, but not a top priority objective. In late 19th and early 20th century, the wealth of the Russian North was on the agenda again in the context of the economic boom and military growth of the leading European powers. In the USSR, the reclamation of the Arctic was limited to the development of natural resources, while the prospects of economic and industrial growth of the North as well as the associated legal regulations were also in prospect. Currently, the Arctic is a primary interest zone for Russia, the main acute issues remaining the reclamation and use of natural resources and legislative regulations of the indigenous peoples' rights.
Abstract
In this work we present the numerical simulation of coolant mixing modes in the T-junction. We shows that the RANS approach is beneficial for a qualitative flow analysis to obtain relatively ...agreed averaged velocity and temperature. Moreover, traditionally, the RANS approach calculates only the averaged temperature distribution. It should also be emphasized that unlike the LES approach, the steady RANS approach cannot express a local flow structure in intense mixing zones. Nevertheless, apparently the used RANS approach should be used for assessing the quality of computational grids, boundary conditions in order to use the LES approach for further numerical simulation.
This article considers the socio-economic development of the Arctic regions of Russia, using the example of some areas of the North-West Federal District. As part of the study the socio-economic ...development of the Arkhangelsk Region, the bordering Republic of Komi, and the Murmansk Region was assessed and analyzed. The analysis was carried out by studying the interaction of variables characterizing the social and economic spheres of human activity in the Arctic zone of Russia. In order to do it a system of indicators was formed. The gross regional product was chosen as a dependent indicator. The main indicators of the economic and social sphere were considered as influencing factors. The assessment was carried out by means of studying interrelations of variables and a comparative analysis of factors affecting the Arctic region. The article provides a literature review on the topic. Besides, the given study describes a methodology for conducting a comparative analysis of the socio-economic development of regions. The methodology includes: goal setting, collecting statistical data, analyzing the dynamics of the estimated indicators, primary processing of time series, bringing them to a normalized form, checking for stationarity using two criteria, bringing them to stationary form, the correlation analysis of the studied parameters, the construction of a regression model for the analysis of each region. In order to compare the socio-economic development of the Arctic regions three independent equations were compiled and the coefficients of equations were determined. The article provides general conclusions on the analysis of the identified interrelations. In the future, the model can be expanded in order to obtain more accurate results and to make the most accurate forecast of the socio-economic development of the analyzed regions.
Using the methods of computational fluid dynamics, an investigation has been conducted into convective heat transfer by a bundle of tubes with heat transfer enhancers in the form of a system of ...spherical dimples made on their outer surface. The presence of enhancers changes the structure of the flow and turbulizes it in the vicinity of dimples, which can lead to a reduction in the length of the wake behind the tube bundle and to a decrease in hydraulic losses due to this. Prospects are shown for the use of enhancers to raise the thermal and aerodynamic efficiency of tube bundles at their various arrangements.
Due to the economic recession resulting from low labor efficiency, a reduction in the number of the employable population and sanctions, constantly sending shock waves throughout the world community, ...Russian consumers have enhanced their consumption of staple foods, bakery products included. Overall production of bakery goods with a three-day shelf life has decreased, since neither minimum income consumers, that is, most of the population, nor retirement-age people can afford them. Conversely, production of shelf-stable low-moisture bakery goods has been increasing. (Crumb moistness is a regulated physicochemical parameter.) Bakery products are everyday goods. Being critical to the food sovereignty and security of the country, they are considered strategic goods. In view of this, the marketing activities of bakery goods manufacturers must accommodate state interests and be consistent with welfare policies. It is of particular importance today as the socio-economic and demographic conditions in Russia remain dire. According to the State Committee on Statistics of the Russian Federation (Goskomstat), about 40% of the country's population have income that is less than the minimum subsistence level, while the annual natural population decline amounted to 218,000 people. The current situation requires that the population be provided with affordable, high-quality bakery products and the interests of manufactures (i.e., profit-making) and society at large be factored in and balanced out. These challenges are met both abroad and somewhat in Russia by applying a concept of enlightened, socially responsible and ethical marketing on a large scale.
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