We present the results of our monitoring study of the IR photometric and spectroscopic variability of the T Tau multiple system. We also present data on the apparent position of T Tau S with respect ...to T Tau N, and two new spatially resolved observations of the T Tau Sa-Sb binary. T Tau N has not varied by more than 0.2 magnitudes in K and L' flux during the 8 years of our observations, though its Br gamma and Br alpha emission line fluxes have varied by nearly a factor of four during this time. For the unresolved T Tau S system, we have derived a 20 year light curve based on our images and on measurements available in the literature. T Tau S varies by 2-3 magnitudes in K and L'-band brightness in a ``redder when faint'' manner, consistent with changes along the line of sight in the amount of material that follows an ISM extinction law. Absorption in the 3.05um water-ice feature is seen only in the spectra of T Tau S and it displays variations in depth and profile. H_2 (2.12 um) emission is also detected only at the position of T Tau S; the H_2, Br gamma and Br alpha emission line fluxes also vary. We have found that the apparent positions of T Tau S with respect to T Tau N and T Tau Sb with respect to Sa are consistent with gravitationally bound orbital motion. The possible orbits of the T Tau S binary imply that Sa is likely the most massive component in this young triple. A reanalysis of the motion of the radio source associated with T Tau S provides no evidence for an ejection event in the T Tau system.
Purpose
There is limited information on how the COVID-19 pandemic has changed health behaviors among cancer patients. We examined changes in exercise behaviors since the pandemic and identified ...characteristics associated with these changes among cancer patients.
Methods
Cancer patients (
n
= 1,210) completed a survey from August to September 2020 to assess COVID-19 pandemic-related changes in health behaviors and psychosocial factors. Patients were categorized into three groups: exercising less, exercising did not change, and exercising more. Patient characteristics were compared by exercise groups.
Results
One-third of the patients reported a decreased amount of regular exercise, while 10% reported exercising more during the pandemic. Patients who exercised less were more likely to be unemployed/retired and have poor health status and psychosocial stressors such as disruptions in daily life while less likely to be former smokers (all
p
< 0.05). In contrast, patients who exercised more were younger, had stage IV diagnosis, and also reported disruptions in daily life (all
p
< 0.05). Patients who were living in rural areas were also more likely not to experience changes in exercise habits (all
p
< 0.05), although rural–urban status was not identified as a strong predictor.
Conclusion
A significant proportion of cancer patients experienced changes in exercise habits, especially exercising less, during the first 6 months of the COVID-19 pandemic. Age, employment status, tumor stage, health status, smoking status, and psychosocial factors were associated with changes in exercise behaviors. Our results highlight the importance of promoting physical activity guidelines for cancer survivorship during the COVID-19 pandemic and may help improve the identification of cancer patients susceptible to exercising less.
Loneliness may exacerbate poor health outcomes particularly among cancer survivors during the COVID-19 pandemic. Little is known about the risk factors of loneliness among cancer survivors. We ...evaluated the risk factors of loneliness in the context of COVID-19 pandemic-related prevention behaviors and lifestyle/psychosocial factors among cancer survivors. Cancer survivors (n = 1471) seen at Huntsman Cancer Institute completed a survey between August–September 2020 evaluating health behaviors, medical care, and psychosocial factors including loneliness during COVID-19 pandemic. Participants were classified into two groups: ‘lonely’ (sometimes, usually, or always felt lonely in past month) and ‘non-lonely’ (never or rarely felt lonely in past month). 33% of cancer survivors reported feeling lonely in the past month. Multivariable logistic regression showed female sex, not living with a spouse/partner, poor health status, COVID-19 pandemic-associated lifestyle factors including increased alcohol consumption and marijuana/CBD oil use, and psychosocial stressors such as disruptions in daily life, less social interaction, and higher perceived stress and financial stress were associated with feeling lonely as compared to being non-lonely (all p < 0.05). A significant proportion of participants reported loneliness, which is a serious health risk among vulnerable populations, particularly cancer survivors. Modifiable risk factors such as unhealthy lifestyle behaviors and psychosocial stress were associated with loneliness. These results highlight the need to screen for unhealthy lifestyle factors and psychosocial stressors to identify cancer survivors at increased risk of loneliness and to develop effective management strategies.
The sequence of the mouse genome is a key informational tool for understanding the contents of the human genome and a key experimental tool for biomedical research. Here, we report the results of an ...international collaboration to produce a high-quality draft sequence of the mouse genome. We also present an initial comparative analysis of the mouse and human genomes, describing some of the insights that can be gleaned from the two sequences. We discuss topics including the analysis of the evolutionary forces shaping the size, structure and sequence of the genomes; the conservation of large-scale synteny across most of the genomes; the much lower extent of sequence orthology covering less than half of the genomes; the proportions of the genomes under selection; the number of protein-coding genes; the expansion of gene families related to reproduction and immunity; the evolution of proteins; and the identification of intraspecies polymorphism.
We present optical spectrophotometric monitoring of four active T Tauri stars (DG Tau, RY Tau, XZ Tau, RW Aur A) at high spectral resolution (R gap 1 x 10 super(4)), to investigate the correlation ...between time variable mass ejection seen in the jet/wind structure of the driving source and time variable mass accretion probed by optical emission lines. This may allow us to constrain the understanding of the jet/wind launching mechanism, the location of the launching region, and the physical link with magnetospheric mass accretion. In 2010, observations were made at six different epochs to investigate how daily and monthly variability might affect such a study. We perform comparisons between the line profiles we observed and those in the literature over a period of decades and confirm the presence of time variability separate from the daily and monthly variability during our observations. This is so far consistent with the idea that these line profiles have a long-term variability (3-20 yr) related to episodic mass ejection suggested by the structures in the extended flow components. We also investigate the correlations between equivalent widths and between luminosities for different lines. We find that these correlations are consistent with the present paradigm of steady magnetospheric mass accretion and emission line regions that are close to the star.
Deconstructing HD 28867 Walter, Frederick M; Beck, Tracy L; Morse, Jon A ...
arXiv.org,
12/2002
Paper
Odprti dostop
The 3" pair of B9 stars, HD 28867, is one of the brightest X-ray sources in the Taurus-Auriga star forming region. In this multi-wavelength study, we attempt to deduce the source of the X-ray ...emission. We show that the East component is the X-ray source. The East component has a near-IR excess and displays narrow absorption lines in the optical, both of which are consistent with a cool stellar companion. This companion is one of the brightest low mass pre-main sequence stars in Tau-Aur; at 2 microns it and the B9 star are equally bright. We see evidence for radial velocity variability in the cool component of >34 km/s. It is not visible in K band speckle imaging, which constrains the companion to lie within 14 AU of the B star. We also report on a possible fourth member of the group, an M1 star 18" south of HD 28867.
Complementary and alternative medicine research has relied primarily on survey data from community populations rather than from patient populations receiving these services in integrated health care ...delivery systems (IHDS).
To describe patients seeking chiropractic, acupuncture, or massage therapy in a dedicated Center for Complementary Medicine (CCM) within an IHDS.
Patient surveys at the initial CCM visit included chief complaint, prior treatments, and relief with treatment (0% to 100% relief). A modified Brief Pain Inventory assessed average and current pain (0 = no pain; 10 = unbearable pain) and interference with life domains (1 = does not interfere; 10 = completely interferes). Demographics and CCM provider type were obtained from medical records. Analysis included patients who completed the survey.
Between 2007 and 2014, a total of 27,225 patients sought CCM services (median age = 50 years). Most (62%) were female, and 73% were white. Modalities included chiropractic (66.9%), acupuncture (18.1%), and massage (15.0%). Spine/truncal pain was most commonly reported (70.5%). A majority of patients (59%) saw their physician for their condition, 59% had not used CCM services previously, and 60% received medications for their condition. Mean ratings included pain relief with prior treatment (30.07%, standard deviation SD = 27.01%), current pain (4.33, SD = 2.4), and functional impairment ranging from 3.03 (SD = 3.09) for relationships to 5.42 (SD = 3.22) for enjoyment of life.
Spine/truncal pain was the most common complaint and chiropractic the most common modality among patients receiving CCM services in an IHDS. More than one-third of patients self-referred to the CCM.
The prevalence of burnout and depressive symptoms is high among physician trainees.
What is the burden of burnout and depressive symptoms among fellows training in pulmonary and critical care ...medicine (PCCM) and what are associated individual fellow, program, and institutional characteristics?
We conducted a cross-sectional electronic survey of fellows enrolled in pulmonary, PCCM, and critical care medicine training programs in the United States to assess burnout and depressive symptoms. Burnout symptoms were measured using the Maslach Burnout Index two-item measure. The two-item Primary Care Evaluation of Mental Disorders Procedure was used to screen for depressive symptoms. For each of the two outcomes (burnout and depressive symptoms), we constructed three multivariate logistic regression models to assess individual fellow characteristics, program structure, and institutional polices associated with either burnout or depressive symptoms.
Five hundred two of the 976 fellows who received the survey completed it—including both outcome measures—giving a response rate of 51%. Fifty percent of fellows showed positive results for either burnout or depressive symptoms, with 41% showing positive results for depressive symptoms, 32% showing positive results for burnout, and 23% showing positive results for both. Reporting a coverage system in the case of personal illness or emergency (adjusted OR aOR, 0.44; 95% CI, 0.26-0.73) and access to mental health services (aOR, 0.14; 95% CI, 0.04-0.47) were associated with lower odds of burnout. Financial concern was associated with higher odds of depressive symptoms (aOR, 1.13; 95% CI, 1.05-1.22). Working more than 70 hours in an average clinical week and the burdens of electronic health record (EHR) documentation were associated with a higher odds of both burnout and depressive symptoms.
Given the high prevalence of burnout and depressive symptoms among fellows training in PCCM, an urgent need exists to identify solutions that address this public health crisis. Strategies such as providing an easily accessible coverage system, access to mental health resources, reducing EHR burden, addressing work hours, and addressing financial concerns among trainees may help to reduce burnout or depressive symptoms and should be studied further by the graduate medical education community.
PurposeThe COVID‐19 pandemic has disrupted many facets of life. We evaluated pandemic‐related health care experiences, COVID‐19 prevention behaviors and measures, health behaviors, and psychosocial ...outcomes among rural and urban cancer patients.MethodsAmong 1,472 adult cancer patients, who visited Huntsman Cancer Institute in the past 4 years and completed a COVID‐19 survey (August‐September 2020), we assessed the impact of the pandemic on medical appointments, prevention/health behaviors, and psychosocial factors, stratified by urbanicity.FindingsMean age was 61 years, with 52% female, 97% non‐Hispanic White, and 27% were residing in rural areas. Rural versus urban patients were more likely to be older, not employed, uninsured, former/current smokers, consume alcohol, and have pandemic‐related changes/cancellations in surgery appointments (all P<.05). Changes/cancellations in other health care access (eg, doctor's visits) were also common, particularly among urban patients. Urban versus rural patients were more likely to socially distance, use masks and hand sanitizer, and experience changes in exercise habits and in their daily lives (all P<.05). Less social interaction and financial stress were common among cancer patients but did not differ by urbanicity.ConclusionsThese findings suggest that the COVID‐19 pandemic had a substantial impact on cancer patients, with several challenges specific to rural patients. This comprehensive study provides unique insights into the first 6 months of COVID‐19 pandemic‐related experiences and continuity of care among rural and urban cancer patients predominantly from Utah. Further research is needed to better characterize the pandemic's short‐ and long‐term effects on rural and urban cancer patients and appropriate interventions.
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