Governments around the world are responding to the coronavirus disease 2019 (COVID-19) pandemic
, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with unprecedented policies ...designed to slow the growth rate of infections. Many policies, such as closing schools and restricting populations to their homes, impose large and visible costs on society; however, their benefits cannot be directly observed and are currently understood only through process-based simulations
. Here we compile data on 1,700 local, regional and national non-pharmaceutical interventions that were deployed in the ongoing pandemic across localities in China, South Korea, Italy, Iran, France and the United States. We then apply reduced-form econometric methods, commonly used to measure the effect of policies on economic growth
, to empirically evaluate the effect that these anti-contagion policies have had on the growth rate of infections. In the absence of policy actions, we estimate that early infections of COVID-19 exhibit exponential growth rates of approximately 38% per day. We find that anti-contagion policies have significantly and substantially slowed this growth. Some policies have different effects on different populations, but we obtain consistent evidence that the policy packages that were deployed to reduce the rate of transmission achieved large, beneficial and measurable health outcomes. We estimate that across these 6 countries, interventions prevented or delayed on the order of 61 million confirmed cases, corresponding to averting approximately 495 million total infections. These findings may help to inform decisions regarding whether or when these policies should be deployed, intensified or lifted, and they can support policy-making in the more than 180 other countries in which COVID-19 has been reported
.
The Global Burden of Disease (GBD) Study 2010 estimated the GBD attributable to 15 categories of skin disease from 1990 to 2010 for 187 countries. For each of the following diseases, we performed ...systematic literature reviews and analyzed resulting data: eczema, psoriasis, acne vulgaris, pruritus, alopecia areata, decubitus ulcer, urticaria, scabies, fungal skin diseases, impetigo, abscess, and other bacterial skin diseases, cellulitis, viral warts, molluscum contagiosum, and non-melanoma skin cancer. We used disability estimates to determine nonfatal burden. Three skin conditions, fungal skin diseases, other skin and subcutaneous diseases, and acne were in the top 10 most prevalent diseases worldwide in 2010, and eight fell into the top 50; these additional five skin problems were pruritus, eczema, impetigo, scabies, and molluscum contagiosum. Collectively, skin conditions ranged from the 2nd to 11th leading cause of years lived with disability at the country level. At the global level, skin conditions were the fourth leading cause of nonfatal disease burden. Using more data than has been used previously, the burden due to these diseases is enormous in both high- and low-income countries. These results argue strongly to include skin disease prevention and treatment in future global health strategies as a matter of urgency.
Abstract
Combining satellite imagery with machine learning (SIML) has the potential to address global challenges by remotely estimating socioeconomic and environmental conditions in data-poor ...regions, yet the resource requirements of SIML limit its accessibility and use. We show that a single encoding of satellite imagery can generalize across diverse prediction tasks (e.g., forest cover, house price, road length). Our method achieves accuracy competitive with deep neural networks at orders of magnitude lower computational cost, scales globally, delivers label super-resolution predictions, and facilitates characterizations of uncertainty. Since image encodings are shared across tasks, they can be centrally computed and distributed to unlimited researchers, who need only fit a linear regression to their own ground truth data in order to achieve state-of-the-art SIML performance.
This study reports a new and significantly enhanced analysis of US flood hazard at 30 m spatial resolution. Specific improvements include updated hydrography data, new methods to determine channel ...depth, more rigorous flood frequency analysis, output downscaling to property tract level, and inclusion of the impact of local interventions in the flooding system. For the first time, we consider pluvial, fluvial, and coastal flood hazards within the same framework and provide projections for both current (rather than historic average) conditions and for future time periods centered on 2035 and 2050 under the RCP4.5 emissions pathway. Validation against high‐quality local models and the entire catalog of FEMA 1% annual probability flood maps yielded Critical Success Index values in the range 0.69–0.82. Significant improvements over a previous pluvial/fluvial model version are shown for high‐frequency events and coastal zones, along with minor improvements in areas where model performance was already good. The result is the first comprehensive and consistent national‐scale analysis of flood hazard for the conterminous US for both current and future conditions. Even though we consider a stabilization emissions scenario and a near‐future time horizon, we project clear patterns of changing flood hazard (3σ changes in 100 years inundated area of −3.8 to +16% at 1° scale), that are significant when considered as a proportion of the land area where human use is possible or in terms of the currently protected land area where the standard of flood defense protection may become compromised by this time.
Plain Language Summary
We develop a method to estimate past, present, and future flood risk for all properties in the conterminous United States whether affected by river, coastal or rainfall flooding. The analysis accounts for variability within environmental factors including changes in sea level rise, hurricane intensity and landfall locations, precipitation patterns, and river discharge. We show that even for a conservative climate change trajectory we can expect locally significant changes in the land area at risk from floods by 2050, and by this time defenses protecting 2,200 km2 of land may be compromised. The complete dataset has been made available via a website (https://floodfactor.com/) created by the First Street Foundation in order to increase public awareness of the threat posed by flooding to safety and livelihoods.
Key Points
First complete high‐resolution flood hazard analysis of conterminous US flood risk from all major sources (fluvial, pluvial, and coastal)
In validation tests the model achieved Critical Success Index scores of 0.69–0.82, similar to many local custom‐built 2D models
By 2050, flood hazard increases for the Eastern seaboard and Western states, but decreases or changes little for the center and South‐West
The Global Burden of Diseases (GBD), Injuries, and Risk Factors study used the disability-adjusted life year (DALY) to quantify the burden of diseases, injuries, and risk factors. This paper provides ...an overview of injury estimates from the 2013 update of GBD, with detailed information on incidence, mortality, DALYs and rates of change from 1990 to 2013 for 26 causes of injury, globally, by region and by country.
Injury mortality was estimated using the extensive GBD mortality database, corrections for ill-defined cause of death and the cause of death ensemble modelling tool. Morbidity estimation was based on inpatient and outpatient data sets, 26 cause-of-injury and 47 nature-of-injury categories, and seven follow-up studies with patient-reported long-term outcome measures.
In 2013, 973 million (uncertainty interval (UI) 942 to 993) people sustained injuries that warranted some type of healthcare and 4.8 million (UI 4.5 to 5.1) people died from injuries. Between 1990 and 2013 the global age-standardised injury DALY rate decreased by 31% (UI 26% to 35%). The rate of decline in DALY rates was significant for 22 cause-of-injury categories, including all the major injuries.
Injuries continue to be an important cause of morbidity and mortality in the developed and developing world. The decline in rates for almost all injuries is so prominent that it warrants a general statement that the world is becoming a safer place to live in. However, the patterns vary widely by cause, age, sex, region and time and there are still large improvements that need to be made.
Furthermore, DALYs measure only direct health loss and, for example, do not consider the economic impact of the NTDs that results from detrimental effects on school attendance and child ...development, agriculture (especially from zoonotic NTDs), and overall economic productivity 10, 11. An additional challenge is to obtain all of the aforementioned values stratified by age and gender, data which are seldom available for NTDs. ...the affordable diagnostic tools typically used to measure NTDs in resource-constrained settings are inaccurate and many sequelae (i.e., morbidities) of NTDs are nonspecific, making it difficult to attribute them to a particular infection or risk factor.
Sea level rise (SLR) may impose substantial economic costs to coastal communities worldwide, but characterizing its global impact remains challenging because SLR costs depend heavily on natural ...characteristics and human investments at each location – including topography, the spatial distribution of assets, and local adaptation decisions. To date, several impact models have been developed to estimate the global costs of SLR. Yet, the limited availability of open-source and modular platforms that easily ingest up-to-date socioeconomic and physical data sources restricts the ability of existing systems to incorporate new insights transparently. In this paper, we present a modular, open-source platform designed to address this need, providing end-to-end transparency from global input data to a scalable least-cost optimization framework that estimates adaptation and net SLR costs for nearly 10 000 global coastline segments and administrative regions. Our approach accounts both for uncertainty in the magnitude of global mean sea level (g.m.s.l.) rise and spatial variability in local relative sea level rise. Using this platform, we evaluate costs across 230 possible socioeconomic and SLR trajectories in the 21st century. According to the latest Intergovernmental Panel on Climate Change Assessment Report (AR6), g.m.s.l. is likely to rise during the 21st century by 0.40–0.69 m if late-century warming reaches 2 ∘C and by 0.58–0.91 m with 4 ∘C of warming (Fox-Kemper et al., 2021). With no forward-looking adaptation, we estimate that annual costs of sea level rise associated with a 2 ∘C scenario will likely fall between USD 1.2 and 4.0 trillion (0.1 % and 1.2 % of GDP, respectively) by 2100, depending on socioeconomic and sea level rise trajectories. Cost-effective, proactive adaptation would provide substantial benefits, lowering these values to between USD 110 and USD 530 billion (0.02 and 0.06 %) under an optimal adaptation scenario. For the likely SLR trajectories associated with 4 ∘C warming, these costs range from USD 3.1 to 6.9 trillion (0.3 % and 2.0 %) with no forward-looking adaptation and USD 200 billion to USD 750 billion (0.04 % to 0.09 %) under optimal adaptation. The Intergovernmental Panel on Climate Change (IPCC) notes that deeply uncertain physical processes like marine ice cliff instability could drive substantially higher global sea level rise, potentially approaching 2.0 m by 2100 in very high emission scenarios. Accordingly, we also model the impacts of 1.5 and 2.0 m g.m.s.l. rises by 2100; the associated annual cost estimates range from USD 11.2 to 30.6 trillion (1.2 % and 7.6 %) under no forward-looking adaptation and USD 420 billion to 1.5 trillion (0.08 % to 0.20 %) under optimal adaptation. Our modeling platform used to generate these estimates is publicly available in an effort to spur research collaboration and support decision-making, with segment-level physical and socioeconomic input characteristics provided at https://doi.org/10.5281/zenodo.7693868 (Bolliger et al., 2023a) and model results at https://doi.org/10.5281/zenodo.7693869 (Bolliger et al., 2023b).
Combining satellite imagery with machine learning (SIML) has the potential to address global challenges by remotely estimating socioeconomic and environmental conditions in data-poor regions, yet the ...resource requirements of SIML limit its accessibility and use. We show that a single encoding of satellite imagery can generalize across diverse prediction tasks (e.g. forest cover, house price, road length). Our method achieves accuracy competitive with deep neural networks at orders of magnitude lower computational cost, scales globally, delivers label super-resolution predictions, and facilitates characterizations of uncertainty. Since image encodings are shared across tasks, they can be centrally computed and distributed to unlimited researchers, who need only fit a linear regression to their own ground truth data in order to achieve state-of-the-art SIML performance.
Working Paper No. 25785 Accumulating evidence indicates that environmental temperature substantially affects economic outcomes and violence, but the reasons for this linkage are not well understood. ...We systematically evaluate the effect of thermal stress on multiple dimensions of economic decisionmaking, judgment, and destructive behavior with 2,000 participants in Kenya and the US who were randomly assigned to different temperatures in a laboratory. We find that most dimensions of decision-making are unaffected by temperature. However, heat causes individuals to voluntarily destroy other participants’ assets, with more pronounced effects during a period of heightened political conflict in Kenya.
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