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zadetkov: 524
1.
  • A SARS-CoV-2 variant elicit... A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy
    Greaney, Allison J; Starr, Tyler N; Eguia, Rachel T ... PLoS pathogens, 02/2022, Letnik: 18, Številka: 2
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    Many SARS-CoV-2 variants have mutations at key sites targeted by antibodies. However, it is unknown if antibodies elicited by infection with these variants target the same or different regions of the ...
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2.
  • Deep Mutational Scanning of... Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding
    Starr, Tyler N.; Greaney, Allison J.; Hilton, Sarah K. ... Cell, 09/2020, Letnik: 182, Številka: 5
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    The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral attachment to ACE2 receptor and is a major determinant of host range and a dominant target of neutralizing ...
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3.
  • Structural basis of SARS-Co... Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement
    McCallum, Matthew; Czudnochowski, Nadine; Rosen, Laura E ... Science (American Association for the Advancement of Science), 02/2022, Letnik: 375, Številka: 6583
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    The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern evades antibody-mediated immunity that comes from vaccination or infection with earlier variants due to ...
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4.
  • Structure-guided covalent s... Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation
    McCallum, Matthew; Walls, Alexandra C; Bowen, John E ... Nature Structural & Molecular Biology, 10/2020, Letnik: 27, Številka: 10
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    SARS-CoV-2 is the causative agent of the COVID-19 pandemic, with 10 million infections and more than 500,000 fatalities by June 2020. To initiate infection, the SARS-CoV-2 spike (S) glycoprotein ...
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5.
  • N-terminal domain antigenic... N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2
    McCallum, Matthew; De Marco, Anna; Lempp, Florian A. ... Cell, 04/2021, Letnik: 184, Številka: 9
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    The SARS-CoV-2 spike (S) glycoprotein contains an immunodominant receptor-binding domain (RBD) targeted by most neutralizing antibodies (Abs) in COVID-19 patient plasma. Little is known about ...
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6.
  • SARS-CoV-2 immune evasion b... SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern
    McCallum, Matthew; Bassi, Jessica; De Marco, Anna ... Science (American Association for the Advancement of Science), 08/2021, Letnik: 373, Številka: 6555
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    A novel variant of concern (VOC) named CAL.20C (B.1.427/B.1.429), which was originally detected in California, carries spike glycoprotein mutations S13I in the signal peptide, W152C in the N-terminal ...
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7.
  • Molecular basis of immune e... Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants
    McCallum, Matthew; Walls, Alexandra C; Sprouse, Kaitlin R ... Science (American Association for the Advancement of Science), 2021-Dec-24, 2021-12-24, 20211224, Letnik: 374, Številka: 6575
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    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission leads to the emergence of variants, including the B.1.617.2 (Delta) variant of concern that is causing a new wave of ...
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8.
  • SARS-CoV-2 breakthrough inf... SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses
    Walls, Alexandra C.; Sprouse, Kaitlin R.; Bowen, John E. ... Cell, 03/2022, Letnik: 185, Številka: 5
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    Although infections among vaccinated individuals lead to milder COVID-19 symptoms relative to those in unvaccinated subjects, the specificity and durability of antibody responses elicited by ...
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9.
  • Mapping Neutralizing and Im... Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology
    Piccoli, Luca; Park, Young-Jun; Tortorici, M. Alejandra ... Cell, 11/2020, Letnik: 183, Številka: 4
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    Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-CoV-2 infection is crucial for understanding immune protection and identifying targets for vaccine design. ...
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10.
  • Lectins enhance SARS-CoV-2 ... Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies
    Lempp, Florian A; Soriaga, Leah B; Montiel-Ruiz, Martin ... Nature (London), 10/2021, Letnik: 598, Številka: 7880
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    SARS-CoV-2 infection-which involves both cell attachment and membrane fusion-relies on the angiotensin-converting enzyme 2 (ACE2) receptor, which is paradoxically found at low levels in the ...
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zadetkov: 524

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