We conducted a rapid, mixed-methods assessment to understand how COVID-19 affected Latinx sexual minority men (LSMM) and transgender women (LTGW). Using a computer-assisted telephone interviewing ...software, one interviewer called 52 participants (randomly sampled from a larger HIV prevention pilot study aiming to increase HIV knowledge and testing frequency; n = 36 LSMM and n = 16 LTGW) between 04/27/20-05/18/20. We quantified core domains using the Epidemic-Pandemic Impacts Inventory scale and provided important context through open-ended qualitative questions assessing: 1) COVID-19 infection history and experiences with quarantine; 2) Health and healthcare access; 3) Employment and economic impact of COVID-19. Participants reported increases in physical conflict or verbal arguments with a partner (13.5%) or other adult(s) (19.2%) due to stressors associated with the safer-at-home order. Participants also reported increased alcohol consumption (23.1%), problems with sleep (67.3%) and mental health (78.4%). Further, disruptions in access to Pre-Exposure Prophylaxis or PrEP-a daily pill to prevent HIV-occurred (33.3% of 18 participants who reported being on PrEP). Many said they received less medical attention than usual (34.6%), and LTGW reported delays in critical gender-affirming hormones/procedures. Half of the participants lost their jobs (50.0%); many undocumented participants relayed additional financial concerns because they did not qualify for financial assistance. Though no COVID-19 infections were noted, COVID-19 dramatically impacted other aspects of health and overall wellbeing of LSMM and LTGW. Public health responses should address the stressors faced by LSMM and LTGW during the COVID-19 pandemic and the impact on wellbeing.
John Hartford Brooks, Ron
Hyperrhiz,
09/2021
23
Journal Article
Recenzirano
Odprti dostop
As a banjo player, John Hartford would eventually go on to found an entirely new genre of music (Newgrass) one that would open up possibilities for many of the musicians we know today: Noam Pikelny, ...Allison Brown, Bela Fleck, Danny Barnes--they all trace some part of their lineage back to him. But what draws me to Hartford is the writing, and the way that his writing reflects the obsession to compose.
Road mortality of animals (roadkill) threatens public safety and wildlife populations. As mitigation tools, predictive models of roadkill are becoming more common in the published literature; ...however, few models generalize across multiple taxa, and thus are less useful for management scenarios that account for multiple target species. Using a dataset of 653 vertebrate roadkills collected from 2 parks in southern Ontario, we constructed generalized linear mixed models to determine the simultaneous risk factors for bird, frog, mammal, five-lined skink (Eumeces fasciatus), snake, toad, and turtle hatchling roadkills from among a set of 8 potential predictor variables. Posted road speed limit was the dominant roadkill predictor (positive coefficient), followed by maximum daily temperature (positive), habitat diversity (positive), and distance from wetlands (negative). All else being equal, as road speed limits increase from 20 km/hr to 50 km/hr, the model predicted the season's mean roadkill probability for a given location to increase from less than 0.1 to 0.75. Conversely, roadkill probability declined from 0.55 to 0.29 as distance from wetland edges increases from 0 km to 1 km. Model diagnostics calculated from randomly resampled cross-validation datasets indicated that the best model formulation had an averaged predictive accuracy of 67.5% and an area under the curve (AUC) of 0.867. The best model also reflected seasonal patterns of animal behavior, including late-summer frog movements and fall turtle hatching events. The best model also compared favorably to single-taxon equivalent models. To reduce the incidence of vertebrate roadkill, we recommend that managers lower road speed limits, especially on roads near diverse habitats and near wetlands, and on warmer days if temporary signage is used.
Background
Surgical techniques to alleviate labia minora hypertrophy are gaining popularity. Due to the rapidly growing number of labiaplasties performed around the world, there is concern for the ...safety of these procedures with respect to maintaining sensitivity to the genitalia and/or implications for sexual arousal.
Objectives
An anatomic study aimed at identifying the nerve density distribution of the labia minora was performed to provide unique insight into performing labiaplasty while preserving sensation.
Methods
Four fresh tissue cadaver labia minora were analyzed. Each labia minora was divided into 6 anatomic areas. The samples from each of the 6 anatomic locations were analyzed for presence of nerve bundles using both a routine hematoxylin and eosin (H&E) stain and a confirmatory immunohistochemical staining for S100 protein. Nerve density was analyzed under light microscopy, counted, and then expressed as percentage nerve density as well as number of bundles per square millimeter.
Results
Upon gross analysis, the raw data reveal that labia minora have a heterogeneous population of sensory nerves. When looking at percent nerve density, the data do not reveal any statistical differences between the anatomic locations.
Conclusions
Most labiaplasty techniques can be performed safely and are unlikely to cause loss of sensation as the nerve density distribution in labia minora is heterogeneous.
In total, 4,200 t/year of salt was used in manufacturing. In addition, the factories used more than 11,000 t/year of alkali and around 3,000 t/year of acid CIP cleaners (Table 3). The majority of ...alkali CIP cleaning chemical was sodium hydroxide (NaOH; 57.5% sodium), usually bought as a 30-42% aqueous solution. In a few cases, sodium carbonate (Na2CO3; 43% sodium), potassium hydroxide (KOH), and a sodium chloride/sodium hydroxide/sodium hypochlorite mixture, were also used.
To develop and pilot-test a Web-based implementation of a team resource management (TRM) intervention to improve medication safety in primary care.
Randomized controlled trial.
Eight practices were ...randomized to either the Web-based TRM or usual practice (4 practices in each group). Primary outcome was adverse drug events (ADEs) in older adults, ascertained using a trigger tool chart review at two 12-month periods (before and after the intervention). The prospective TRM approach, designed to inculcate ownership and empowerment, facilitates systematic appraisal of risk and error reduction. This approach uses the highly adaptable and transferable Safety Enhancement and Monitoring Instrument that is Patient Centered.
The rate of ADEs decreased from 25.8 to 18.3 per 100 patients per year in the intervention group. The rate was virtually unchanged in the control group (24.3 vs 24.8). In an analysis of covariance at the practice level, being in the intervention group was associated with a lower rate of ADEs. The interaction between time (preintervention vs postintervention) and group (intervention vs control) was not signifi cant (P = .104) but showed a trend toward a decrease in the intervention group compared with the control group over time.
The Web-based TRM intervention proved feasible and demonstrated potential for effectiveness in various ambulatory settings. This pilot study was limited by small size and short follow-up period. Future studies should test the intervention on a larger scale over a longer period of time and should explore methods for overcoming common barriers to change.
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