Object
To analyze geometrical approaches, prescription modalities, and delivery efficiency for linear accelerator (Linac)-based STereotactic Arrhythmia Radioablation (STAR) for ventricular ...tachycardia.
Methods
The anatomy and planning target volume (PTV) of the first Italian STAR patient were used. To assess geometrical approaches, 3 plans prescribed to 75% isodose-line, differing for number, length of arcs, and couch rotations, were generated and compared (Plans#1–3). Volumetric-arc with 6-MV flattening-filter-free (FFF) was employed. To evaluate prescription modality and delivery, the best geometrical plan was compared with other plans prescribed on 70%, 65%, and 60% isodose-line and with another one using 10MV-FFF beams (Plans#4–7).
Results
For Plans#1–3, PTV coverage, mean cardiac dose, monitor units (MUs), and beam-delivery-time (BDT) were 96–98.5%, 4.9–5.2 Gy, 7047–7790, and 5–6 min, respectively. Plans#4–7 were similar in terms of mean cardiac dose, MUs and BDT to Plans#1–3, except in maximum dose and lower time for 10MV-FFF plan.
Conclusion
Linac-based STAR is safe and efficient in terms of BDT and MUs. To ensure high dose to PTV, different dose prescription modalities should be evaluated. The 10FFF approach was the faster but not suitable in patient with cardiac implantable electronic devices.
After pioneering gaseous detectors of single photon for RICH applications using CsI solid state photocathodes in MWPCs within the RD26 collaboration and by the constructions for the RICH detector of ...the COMPASS experiment at CERN SPS, in 2016 we have upgraded COMPASS RICH by novel gaseous photon detectors based on MPGD technology. Four novel photon detectors, covering a total active area of 1.5m2 have been installed in order to cope with the challenging efficiency and stability requirements of the COMPASS physics programme. They are the first application in an experiment of MPGD-based single photon detectors. All aspects of the upgrade are presented, including engineering, mass production, quality assessment and performance.
Perspectives for further developments in the field of gaseous single photon detectors are also presented.
The novel MPGD-based photon detectors of COMPASS RICH-1 consist of large-size hybrid MPGDs with multi-layer architecture including two layers of Thick-GEMs and a bulk resistive MicroMegas. The top ...surface of the first THGEM is coated with a CsI film which also acts as photo-cathode. These detectors have been successfully in operation at COMPASS since 2016. Concerning bias-voltage supply, the Thick-GEMs are segmented in order to reduce the energy released in case of occasional discharges, while the MicroMegas anode is segmented into pads individually biased with positive voltage while the micromesh is grounded. In total, there are about ten different electrode types and more than 20000 electrodes supplied by more than 100 HV channels, where appropriate correlations among the applied voltages are required for the correct operation of the detectors. Therefore, a robust control system is mandatory, implemented by a custom designed software package, while commercial power supply units are used. This sophisticated control system allows to protect the detectors against errors by the operator, to monitor and log voltages and currents at 1 Hz rate, and automatically react to detector misbehavior. In addition, a voltage compensation system has been developed to automatically adjust the biasing voltage according to environmental pressure and temperature variations, to achieve constant gain over time. This development answers to a more general need. In fact, voltage compensation is always a requirement for the stability of gaseous detectors and its need is enhanced in multi-layer ones.
In this paper, the HV system and its performance are described in details, as well as the stability of the novel MPGD-based photon detectors during the physics data taking at COMPASS.
Experiments at the future Electron Ion Collider require excellent hadron identification in a broad momentum range, in harsh conditions. A RICH capable to fulfill the PID requirements of the EIC could ...use MPGD-based photon detectors with solid photocathodes for covering large surfaces at affordable cost, providing good effciency, high resolution and compatibility with magnetic field. Photon detectors realized by coupling THGEMs and Micromegas have been successfully operated at the RICH-1 detector of the COMPASS Experiment at CERN since 2016. A similar technology could be envisaged for an EIC RICH, provided a large improvement in the photon position resolution is achieved. An R&D effort in this direction is ongoing at INFN Trieste. Few prototypes with smaller pixel size (down to 3 mm x 3 mm) have been built and tested in the laboratory with X-Ray and UV LED light sources. A modular mini-pad detector prototype has also been tested at the CERN SPS H4 beamline. New data acquisition and analysis software called Raven DAQ and Raven Decoder have been developed and used with the APV-25 based Scalable Readout System (SRS), for the modular mini-pad prototype tests. The main characteristics of the new mini-pad hybrid MPGD-based detector of single photons are described and preliminary results of laboratory and beam tests are presented.
In high momenta range, the construction of a Ring Imaging CHerenkov (RICH) detector for the particle identification at the future Electron Ion Collider (EIC) is a complicated task. A compact collider ...setup imposes to construct a RICH with a short radiator length, hence limiting the number of photons. The number of photons can be increase by choosing to work in far UV region. However, as standard fused-silica windows are opaque below 165 nm, therefore, a windowless RICH approach could be a possible choice. In the far UV range, CsI is a widely used photo-cathode (PC) to detect photons, but because of its hygroscopic nature, it is very delicate to handle. Its Quantum Efficiency (QE) degrades in high intensity ion fluxes. These are the key reasons to search a novel, less delicate PC with sensitivity in the far UV region. Hydrogenated nanodiamond films are proposed as an alternative PC material and shown to have promising characteristics. The performance of nanodiamond PC coupled to THGEM-based detectors is the objects of our ongoing R & D.
The first phase of these studies includes the characterization of THGEMs coated with nanodiamont PC, the comparison of the effective QE in vacuum and in gaseous atmospheres, the hardness respect to the PC bombardment by ions from the multiplication process. The approach is described in detail as well as all the results obtained so far with these exploratory studies.
In 2016 we have upgraded the COMPASS RICH by novel gaseous photon detectors based on MPGD technology. Four new photon detectors, covering a total active area of 1.5
m
2
, have been installed in order ...to cope with the challenging efficiency and stability requirements of the COMPASS physics programme. The new detector architecture consists in a hybrid MPGD combination: two layers of THGEMs, the first of which also acts as a reflective photocathode thanks to CsI coating, are coupled to a bulk Micromegas on a pad-segmented anode. These detectors are the first application in an experiment of MPGD-based single photon detectors. Presently, we are further developing the MPGD-based PDs to make them adequate for a setup at the future EIC collider. All aspects of the COMPASS RICH-1 Photon Detectors upgrade are presented: R&D, engineering, mass production, QA and performance; the on-going development for collider application is also presented.
The design of a Ring Imaging CHerenkov (RICH) detector for the identification of high momentum particles at the future Electron Ion Collider (EIC) is extremely challenging by using current ...technology. Compact collider setups impose to construct RICH with short radiator length, hence limiting the number of generated photons. The number of detected photons can be increased by selecting the far UV region. As standard fused-silica windows is opaque below 165 nm, a windowless RICH can be a possible approach. CsI is widely used photocathode (PC) for photon detection in the far UV range. Due to its hygroscopic nature it is very delicate to handle. In addition, its Quantum Effciency (QE) degrades in high intensity ion fluxes. These are the key reasons to quest for novel PC with sensitivity in the far UV region. Recent development of layers of hydrogenated nanodiamond powders as an alternative PC material and their performance, when coupled to the THick Gaseous Electron Multipliers (THGEM)-based detectors, are the objects of an ongoing R&D. We report here some preliminary results on the initial phase of these studies.
We report about the development status of large area gaseous single photon detectors based on a novel hybrid concept for RICH applications.
The hybrid concept combines Thick Gaseous Electron ...Multipliers (THGEMs) coupled to CsI, working as a photon sensitive pre-amplification stage, and Micromegas, as a multiplication stage. The most recent achievements within the research and development programme consist in the assembly and study of 300×300mm2 hybrid photon detectors, the optimization of front-end electronics, and engineering towards large area detectors. Hybrid detectors with an active area of 300×300mm2 have been successfully operated in laboratory conditions and at a CERN PS T10 test beam, achieving effective gains in the order of 105 and good time resolution (σ=7ns); APV25 front-end chips have been coupled to the detector resulting in noise levels lower than 1000 electrons; the production and characterization of 300×600mm2 THGEMs is ongoing.
A set of hybrid detectors with 600×600mm2 active area is envisaged to upgrade COMPASS RICH-1 at CERN in 2016.
•The hybrid detector is a novel concept for large area gaseous photon detectors.•The hybrid concept combines Thick Gaseous Electron Multipliers and Micromegas.•The COMPASS RICH-1 upgrade will adopt hybrid detectors to replace the existing MWPCs
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