We studied the effect of fibroblast growth factor receptor 3 (FGFR3) inhibitor BGJ-398 on the differentiation of bone marrow mesenchymal stem cells (BM MSC) into osteoblasts in wild type (wt) mice ...and in animals with mutation in
TBXT
gene (mt) and possible differences in the pluripotency of these cells. Cytology tests showed that the cultured BM MSC could differentiate into osteoblasts and adipocytes. The effect of different BGJ-398 concentrations on the expression of
FGFR3
,
RUNX2
,
SMAD1
,
SMAD4
,
SMAD5
,
SMAD6
,
SMAD7
, and
SMAD8
were studied by quantitative reverse transcription PCR. The expression of
RUNX2
protein was evaluated by Western blotting. BM MSC of mt and wt mice did not differ in pluripotency and expressed the same membrane marker antigens. BGJ-398 inhibitor reduced the expression of
FGFR3
and
RUNX2
. In BM MSC from mt and wt mice have similar gene expression (and its changing) in
FGFR3
,
RUNX2
,
SMAD1
,
SMAD4
,
SMAD5
,
SMAD6
,
SMAD7
, and
SMAD8
genes. Thus, our experiments confirmed the effect of decreased expression of
FGFR3
on osteogenic differentiation of BM MSC from wt and mt mice. However, BM MSC from mt and wt mice did not differ in pluripotency and are an adequate model for laboratory research.
We investigate radial excitation of the quark-antiquark pair in the π 0 meson and its effects on the γγ∗ → π0 transition form factor in the framework of light cone perturbative QCD. The existing ...constraints on the light cone wave function of the lowest Fock state | qq ⟩ in the π0 meson allow a sizeable radial excitation of the quark-antiquark pair. We construct the light cone wave function for the quark-antiquark pair in the first radially excited state (the 2S state) using a simple harmonic oscillator potential. The distribution amplitude obtained for the 2S state has two nodes in x at low scale of Q and thereby has a much strong scale dependence than the 1S state. Contributions from this radial excitation to the γγ∗ → π0 transition form factor exhibit different Q2-dependence behavior from the ground state and thus can modify the prediction for the transition form factor in the medium-large region of Q2.
Observation of e+e- → γX(3872) at BESIII Achasov, M N; Albayrak, O; Ambrose, D J ...
Physical review letters,
2014-Mar-07, Letnik:
112, Številka:
9
Journal Article
Recenzirano
Odprti dostop
With data samples collected with the BESIII detector operating at the BEPCII storage ring at center-of-mass energies from 4.009 to 4.420 GeV, the process e+e-→ γX(3872) is observed for the first time ...with a statistical significance of 6.3σ. The measured mass of the X(3872) is (3871.9 ± 0.7s tat ± 0.2 syst) MeV/c(2), in agreement with previous measurements. Measurements of the product of the cross section σe+e- → γX(3872) and the branching fraction BX(3872)→π+π-J/ψ at center-of-mass energies 4.009, 4.229, 4.260, and 4.360 GeV are reported. Our measurements are consistent with expectations for the radiative transition process Y(4260) → γX(3872).
The recent discovery of superconductivity with a transition temperature (T(c)) at 18 K in K(x)picene has extended the possibility of high-T(c) superconductors in organic materials. Previous ...experience based on similar hydrocarbons, like alkali-metal doped phenanthrene, suggested that even higher transition temperatures might be achieved in alkali-metals or alkali-earth-metals doped such polycyclic-aromatic-hydrocarbons (PAHs), a large family of molecules composed of fused benzene rings. Here we report the discovery of high-T(c) superconductivity at 33 K in K-doped 1,2:8,9-dibenzopentacene (C(30)H(18)). To our best knowledge, it is higher than any T(c) reported previously for an organic superconductor under ambient pressure. This finding provides an indication that superconductivity at much higher temperature may be possible in such PAHs system and is worthy of further exploration.
Observation of η ′ → π + π − μ + μ Achasov, M. N.; Adlarson, P.; Ahmed, S. ...
Physical review. D,
04/2021, Letnik:
103, Številka:
7
Journal Article
Recenzirano
Odprti dostop
Using ( 1310.6 ± 7.0 ) × 106 J / ψ events acquired with the BESIII detector at the BEPCII storage rings, the decay η ′ → π+ π−μ+μ− is observed for the first time with a significance of 8 σ via the ...process J / ψ → γ η ′ . We measure the branching fraction of η ′ → π+ π−μ+μ− to be B ( η ′ → π+ π−μ+μ− ) = ( 1.97 ± 0.33 ( stat ) ± 0.19 ( syst ) ) × 10−5, where the first and second uncertainties are statistical and systematic, respectively.
We report the measurement of the inclusive cross sections for e^{+}e^{-}→nOCH (where nOCH denotes non-open charm hadrons) with improved precision at center-of-mass (c.m.) energies from 3.645 to ...3.871 GeV. We observe three resonances: R(3760), R(3780), and R(3810) with significances of 8.1σ, 13.7σ, and 8.8σ, respectively. The R(3810) state is observed for the first time, while the R(3760) and R(3780) states are observed for the first time in the nOCH cross sections. Two sets of resonance parameters describe the energy-dependent line shape of the cross sections well. In set I set II, the R(3810) state has mass (3805.7±1.1±2.7) (3805.7±1.1±2.7) MeV/c^{2}, total width (11.6±2.9±1.9) (11.5±2.8±1.9) MeV, and an electronic width multiplied by the nOCH decay branching fraction of (10.9±3.8±2.5) (11.0±3.4±2.5) eV. In addition, we measure the branching fractions BR(3760)→nOCH=(25.2±16.1±30.4)%(6.4±4.8±7.7)% and BR(3780)→nOCH=(12.3±6.6±8.3)%(10.4±4.8±7.0)% for the first time. The R(3760) state can be interpreted as an open-charm (OC) molecular state, but containing a simple four-quark state component. The R(3810) state can be interpreted as a hadrocharmonium state.
Using (10087±44)×10^{6} J/ψ events collected with the BESIII detector, numerous Ξ^{-} and Λ decay asymmetry parameters are simultaneously determined from the process J/ψ→Ξ^{-}Ξover ...¯^{+}→Λ(pπ^{-})π^{-}Λover ¯(nover ¯π^{0})π^{+} and its charge-conjugate channel. The precisions of α_{Λ0} for Λ→nπ^{0} and αover ¯_{Λ0} for Λover ¯→nover ¯π^{0} compared to world averages are improved by factors of 4 and 1.7, respectively. The ratio of decay asymmetry parameters of Λ→nπ^{0} to that of Λ→pπ^{-}, ⟨α_{Λ0}⟩/⟨α_{Λ-}⟩, is determined to be 0.873±0.012_{-0.010}^{+0.011}, where the first and the second uncertainties are statistical and systematic, respectively. The ratio is smaller than unity more than 5σ, which signifies the existence of the ΔI=3/2 transition in Λ for the first time. Besides, we test for CP symmetry in Ξ^{-}→Λπ^{-} and in Λ→nπ^{0} with the best precision to date.
The quantum entangled J/ψ→Σ^{+}Σover ¯^{-} pairs from (1.0087±0.0044)×10^{10} J/ψ events taken by the BESIII detector are used to study the nonleptonic two-body weak decays Σ^{+}→nπ^{+} and Σover ...¯^{-}→nover ¯π^{-}. The CP-odd weak decay parameters of the decays Σ^{+}→nπ^{+} (α_{+}) and Σover ¯^{-}→nover ¯π^{-} (αover ¯_{-}) are determined to be 0.0481±0.0031_{stat}±0.0019_{syst} and -0.0565±0.0047_{stat}±0.0022_{syst}, respectively. The decay parameter αover ¯_{-} is measured for the first time, and the accuracy of α_{+} is improved by a factor of 4 compared to the previous results. The simultaneously determined decay parameters allow the first precision CP symmetry test for any hyperon decay with a neutron in the final state with the measurement of A_{CP}=(α_{+}+αover ¯_{-})/(α_{+}-αover ¯_{-})=-0.080±0.052_{stat}±0.028_{syst}. Assuming CP conservation, the average decay parameter is determined as ⟨α_{+}⟩=(α_{+}-αover ¯_{-})/2=-0.0506±0.0026_{stat}±0.0019_{syst}, while the ratios α_{+}/α_{0} and αover ¯_{-}/αover ¯_{0} are -0.0490±0.0032_{stat}±0.0021_{syst} and -0.0571±0.0053_{stat}±0.0032_{syst}, where α_{0} and αover ¯_{0} are the decay parameters of the decays Σ^{+}→pπ^{0} and Σover ¯^{-}→pover ¯π^{0}, respectively.
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