To cite this article: Boyle RJ, Ismail IH, Kivivuori S, Licciardi PV, Robins-Browne RM, Mah L-J, Axelrad C, Moore S, Donath S, Carlin JB, Lahtinen SJ, Tang MLK. Lactobacillus GG treatment during ...pregnancy for the prevention of eczema: a randomized controlled trial. Allergy 2011; 66: 509-516. ABSTRACT: Background: Probiotic supplementation in early life may be effective for preventing eczema. Previous studies have suggested that prenatal administration may be particularly important for beneficial effects. Objective: We examined whether prenatal treatment with the probiotic Lactobacillus rhamnosus GG (LGG) can influence the risk of eczema during infancy. Methods: We recruited 250 pregnant women carrying infants at high risk of allergic disease to a randomized controlled trial of probiotic supplementation (LGG 1.8 × 10¹⁰ cfu/day) from 36 weeks gestation until delivery. Infants were assessed during their first year for eczema or allergic sensitization. Immunological investigations were performed in a subgroup. Umbilical cord blood was examined for dendritic cell and regulatory T cell numbers and production of TGFβ, IL-10, IL-12, IL-13, IFN-γ and TNFα. Maternal breast milk was examined for total IgA, soluble CD14 and TGFβ. Results: Prenatal probiotic treatment was not associated with reduced risk of eczema (34% probiotic, 39% placebo; RR 0.88; 95% CI 0.63, 1.22) or IgE-associated eczema (18% probiotic, 19% placebo; RR 0.94; 95% CI 0.53, 1.68). Prenatal probiotic treatment was not associated with any change in cord blood immune markers, but was associated with decreased breast milk soluble CD14 and IgA levels. Conclusions: Prenatal treatment with Lactobacillus rhamnosus GG was not sufficient for preventing eczema. If probiotics are effective for preventing eczema, then a postnatal component to treatment or possibly an alternative probiotic strain is necessary.
Abstract
We report the discovery of Pegasus IV, an ultra-faint dwarf galaxy found in archival data from the Dark Energy Camera processed by the DECam Local Volume Exploration Survey. Pegasus IV is a ...compact, ultra-faint stellar system (
r
1
/
2
=
41
−
6
+
8
pc;
M
V
= −4.25 ± 0.2 mag) located at a heliocentric distance of
90
−
6
+
4
kpc
. Based on spectra of seven nonvariable member stars observed with Magellan/IMACS, we confidently resolve Pegasus IV’s velocity dispersion, measuring
σ
v
=
3.3
−
1.1
+
1.7
km s
−1
(after excluding three velocity outliers); this implies a mass-to-light ratio of
M
1
/
2
/
L
V
,
1
/
2
=
167
−
99
+
224
M
⊙
/
L
⊙
for the system. From the five stars with the highest signal-to-noise spectra, we also measure a systemic metallicity of Fe/H =
−
2.63
−
0.30
+
0.26
dex, making Pegasus IV one of the most metal-poor ultra-faint dwarfs. We tentatively resolve a nonzero metallicity dispersion for the system. These measurements provide strong evidence that Pegasus IV is a dark-matter-dominated dwarf galaxy, rather than a star cluster. We measure Pegasus IV’s proper motion using data from Gaia Early Data Release 3, finding (
μ
α
*
,
μ
δ
) = (0.33 ± 0.07, −0.21 ± 0.08) mas yr
−1
. When combined with our measured systemic velocity, this proper motion suggests that Pegasus IV is on an elliptical, retrograde orbit, and is currently near its orbital apocenter. Lastly, we identify three potential RR Lyrae variable stars within Pegasus IV, including one candidate member located more than 10 half-light radii away from the system’s centroid. The discovery of yet another ultra-faint dwarf galaxy strongly suggests that the census of Milky Way satellites is still incomplete, even within 100 kpc.
Abstract
We present the discovery of DELVE 6, an ultra-faint stellar system identified in the second data release of the DECam Local Volume Exploration (DELVE) survey. Based on a maximum-likelihood ...fit to its structure and stellar population, we find that DELVE 6 is an old (
τ
> 9.8 Gyr at 95% confidence) and metal-poor (Fe/H < −1.17 dex at 95% confidence) stellar system with an absolute magnitude of
M
V
=
−
1.5
−
0.6
+
0.4
mag and an azimuthally averaged half-light radius of
r
1
/
2
=
10
−
3
+
4
pc. These properties are consistent with the population of ultra-faint star clusters uncovered by recent surveys. Interestingly, DELVE 6 is located at an angular separation of ∼10° from the center of the Small Magellanic Cloud (SMC), corresponding to a 3D physical separation of ∼20 kpc given the system’s observed distance (
D
⊙
= 80 kpc). This also places the system ∼35 kpc from the center of the Large Magellanic Cloud (LMC), lying within recent constraints on the size of the LMC’s dark matter halo. We tentatively measure the proper motion of DELVE 6 using data from Gaia, which we find supports a potential association between the system and the LMC/SMC. Although future kinematic measurements will be necessary to determine its origins, we highlight that DELVE 6 may represent only the second or third ancient (
τ
> 9 Gyr) star cluster associated with the SMC, or one of fewer than two dozen ancient clusters associated with the LMC. Nonetheless, we cannot currently rule out the possibility that the system is a distant Milky Way halo star cluster.
Abstract
We present the second public data release (DR2) from the DECam Local Volume Exploration survey (DELVE). DELVE DR2 combines new DECam observations with archival DECam data from the Dark ...Energy Survey, the DECam Legacy Survey, and other DECam community programs. DELVE DR2 consists of ∼160,000 exposures that cover >21,000 deg
2
of the high-Galactic-latitude (∣
b
∣ > 10°) sky in four broadband optical/near-infrared filters (
g
,
r
,
i
,
z
). DELVE DR2 provides point-source and automatic aperture photometry for ∼2.5 billion astronomical sources with a median 5
σ
point-source depth of
g
= 24.3,
r
= 23.9,
i
= 23.5, and
z
= 22.8 mag. A region of ∼17,000 deg
2
has been imaged in all four filters, providing four-band photometric measurements for ∼618 million astronomical sources. DELVE DR2 covers more than 4 times the area of the previous DELVE data release and contains roughly 5 times as many astronomical objects. DELVE DR2 is publicly available via the NOIRLab Astro Data Lab science platform.
Abstract
We report the discovery of a new ultra-faint stellar system found near the Magellanic Clouds in the DECam Local Volume Exploration Survey. This new system, DELVE J0155−6815 (DELVE 2), is ...located at a heliocentric distance of
D
⊙
= 71 ± 4 kpc, which places it at a 3D physical separation of 12 ± 3 kpc from the center of the Small Magellanic Cloud and
from the center of the Large Magellanic Cloud (LMC). DELVE 2 is identified as a resolved overdensity of old (
τ
> 13.3 Gyr) and metal-poor (
dex) stars with a projected half-light radius of
and an absolute magnitude of
. The size and luminosity of DELVE 2 are consistent with both the population of recently discovered ultra-faint globular clusters and the smallest ultra-faint dwarf galaxies. However, its photometrically derived age and metallicity would place it among the oldest and most metal-poor globular clusters in the Magellanic system. In the absence of spectroscopic measurements of the system’s metallicity dispersion and internal kinematics, we are unable to conclusively classify this system at this time. DELVE 2 is detected in
Gaia
DR2 with a clear proper-motion signal, with multiple blue horizontal-branch stars near the centroid of the system with proper motions consistent with the systemic mean. We measure the system proper motion to be
=
mas yr
−1
. We compare the spatial position and proper motion of DELVE 2 with simulations of the accreted satellite population of the LMC and find that it is very likely to be associated with the LMC.
ABSTRACT
We perform analysis of the 3D kinematics of Milky Way disc stars in mono-age populations. We focus on stars between Galactocentric distances of R = 6 and 14 kpc, selected from the combined ...LAMOST Data Release 4 (DR4) red clump giant stars and Gaia DR2 proper motion catalogue. We confirm the 3D asymmetrical motions of recent works and provide time tagging of the Galactic outer disc asymmetrical motions near the anticentre direction out to Galactocentric distances of 14 kpc. Radial Galactocentric motions reach values up to 10 km s−1, depending on the age of the population, and present a north–south asymmetry in the region corresponding to density and velocity substructures that were sensitive to the perturbations in the early 6 Gyr. After that time, the disc stars in this asymmetrical structure have become kinematically hotter, and are thus not sensitive to perturbations, and we find the structure is a relatively younger population. With quantitative analysis, we find stars both above and below the plane at R ≳ 9 kpc that exhibit bending mode motions of which the sensitive duration is around 8 Gyr. We speculate that the in-plane asymmetries might not be mainly caused by a fast rotating bar, intrinsically elliptical outer disc, secular expansion of the disc, or streams. Spiral arm dynamics, out-of-equilibrium models, minor mergers or others are important contributors. Vertical motions might be dominated by bending and breathing modes induced by complicated inner or external perturbers. It is likely that many of these mechanisms are coupled together.
Abstract
We present a spectroscopic analysis of Eridanus IV (Eri IV) and Centaurus I (Cen I), two ultrafaint dwarf galaxies of the Milky Way. Using IMACS/Magellan spectroscopy, we identify 28 member ...stars of Eri IV and 34 member stars of Cen I. For Eri IV, we measure a systemic velocity of
v
sys
=
−
31.5
−
1.2
+
1.3
km
s
−
1
, and velocity dispersion
σ
v
=
6.1
−
0.9
+
1.2
km
s
−
1
. Additionally, we measure the metallicities of 16 member stars of Eri IV. We find a metallicity of
Fe
/
H
=
−
2.87
−
0.07
+
0.08
, and resolve a dispersion of
σ
Fe/H
=0.20 ± 0.09. The mean metallicity is marginally lower than all other known ultrafaint dwarf galaxies, making it one of the most metal-poor galaxies discovered thus far. Eri IV also has a somewhat unusual right-skewed metallicity distribution. For Cen I, we find a velocity
v
sys
= 44.9 ± 0.8 km s
−1
, and velocity dispersion
σ
v
=
4.2
−
0.5
+
0.6
km
s
−
1
. We measure the metallicities of 27 member stars of Cen I, and find a mean metallicity Fe/H = −2.57 ± 0.08, and metallicity dispersion
σ
Fe
/
H
=
0.38
−
0.05
+
0.07
. We calculate the systemic proper motion, orbit, and the astrophysical J-factor for each system, the latter of which indicates that Eri IV is a good target for indirect dark matter detection. We also find no strong evidence for tidal stripping of Cen I or Eri IV. Overall, our measurements confirm that Eri IV and Cen I are dark-matter-dominated galaxies with properties largely consistent with other known ultrafaint dwarf galaxies. The low metallicity, right-skewed metallicity distribution, and high J-factor make Eri IV an especially interesting candidate for further follow-up.
ABSTRACT
Tidal features in the outskirts of galaxies yield unique information about their past interactions and are a key prediction of the hierarchical structure formation paradigm. The Vera C. ...Rubin Observatory is poised to deliver deep observations for potentially millions of objects with visible tidal features, but the inference of galaxy interaction histories from such features is not straightforward. Utilizing automated techniques and human visual classification in conjunction with realistic mock images produced using the NewHorizon cosmological simulation, we investigate the nature, frequency, and visibility of tidal features and debris across a range of environments and stellar masses. In our simulated sample, around 80 per cent of the flux in the tidal features around Milky Way or greater mass galaxies is detected at the 10-yr depth of the Legacy Survey of Space and Time (30–31 mag arcsec−2), falling to 60 per cent assuming a shallower final depth of 29.5 mag arcsec−2. The fraction of total flux found in tidal features increases towards higher masses, rising to 10 per cent for the most massive objects in our sample (M⋆ ∼ 1011.5 M⊙). When observed at sufficient depth, such objects frequently exhibit many distinct tidal features with complex shapes. The interpretation and characterization of such features varies significantly with image depth and object orientation, introducing significant biases in their classification. Assuming the data reduction pipeline is properly optimized, we expect the Rubin Observatory to be capable of recovering much of the flux found in the outskirts of Milky Way mass galaxies, even at intermediate redshifts (z < 0.2).
Abstract
We report the discovery of six ultra-faint Milky Way satellites identified through matched-filter searches conducted using Dark Energy Camera (DECam) data processed as part of the second ...data release of the DECam Local Volume Exploration (DELVE) survey. Leveraging deep Gemini/GMOS-N imaging (for four candidates) as well as follow-up DECam imaging (for two candidates), we characterize the morphologies and stellar populations of these systems. We find that these candidates all share faint absolute magnitudes (
M
V
≥ −3.2 mag) and old, metal-poor stellar populations (
τ
> 10 Gyr, Fe/H < −1.4 dex). Three of these systems are more extended (
r
1/2
> 15 pc), while the other three are compact (
r
1/2
< 10 pc). From these properties, we infer that the former three systems (Boötes V, Leo Minor I, and Virgo II) are consistent with ultra-faint dwarf galaxy classifications, whereas the latter three (DELVE 3, DELVE 4, and DELVE 5) are likely ultra-faint star clusters. Using data from the Gaia satellite, we confidently measure the proper motion of Boötes V, Leo Minor I, and DELVE 4, and tentatively detect a proper-motion signal from DELVE 3 and DELVE 5; no signal is detected for Virgo II. We use these measurements to explore possible associations between the newly discovered systems and the Sagittarius dwarf spheroidal, the Magellanic Clouds, and the Vast Polar Structure, finding several plausible associations. Our results offer a preview of the numerous ultra-faint stellar systems that will soon be discovered by the Vera C. Rubin Observatory and highlight the challenges of classifying the faintest stellar systems.
Abstract
The DECam Local Volume Exploration survey (DELVE) is a 126-night survey program on the 4 m Blanco Telescope at the Cerro Tololo Inter-American Observatory in Chile. DELVE seeks to understand ...the characteristics of faint satellite galaxies and other resolved stellar substructures over a range of environments in the Local Volume. DELVE will combine new DECam observations with archival DECam data to cover ∼15,000 deg
2
of high Galactic latitude (∣
b
∣ > 10°) southern sky to a 5
σ
depth of
g
,
r
,
i
,
z
∼ 23.5 mag. In addition, DELVE will cover a region of ∼2200 deg
2
around the Magellanic Clouds to a depth of
g
,
r
,
i
∼ 24.5 mag and an area of ∼135 deg
2
around four Magellanic analogs to a depth of
g
,
i
∼ 25.5 mag. Here, we present an overview of the DELVE program and progress to date. We also summarize the first DELVE public data release (DELVE DR1), which provides point-source and automatic aperture photometry for ∼520 million astronomical sources covering ∼5000 deg
2
of the southern sky to a 5
σ
point-source depth of
g
= 24.3 mag,
r
= 23.9 mag,
i
= 23.3 mag, and
z
= 22.8 mag. DELVE DR1 is publicly available via the NOIRLab Astro Data Lab science platform.
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