Síndrome de Kounis, a propósito de un caso Mendez Betancurt, Johan Leandro; Ramírez Ramos, Cristhian Felipe; Osorio Carmona, Hugo E ...
Acta médica peruana,
01/2018, Letnik:
35, Številka:
1
Journal Article
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El síndrome de Kounis se caracteriza por un compromiso cardiaco que es secundario a una respuesta alérgica. Hay pocos datos acerca de la epidemiologia de esta enfermedad debido a su reciente ...descripción. Se presenta el caso de una paciente mujer de 46 años sin antecedentes de importancia que presentó dolor tipo cólico episódico en hipocondrio derecho de 4 días de tiempo de enfermedad, en la que se consideró el diagnóstico de cólico de origen biliar. Quince minutos luego de manejo sintomático (hiocsina/dipirona), la paciente presentó dolor torácico en región precordial de inicio súbito. La evaluación física mostró hipotensión, taquicardia, presencia de habones en todo el cuerpo y sibilantes a la auscultación pulmonar. El electrocardiograma mostro infradesnivel del segmento ST. Considerado como síndrome coronario agudo, se realizó el manejo con esteroides y soporte vital, y se indicó monitorización cardiovascular en unidad de cuidados intensivos. La paciente egresó sin complicación luego de unos días.
In September 2014 there was a sharp increase in the seismic activity of the Bransfield Strait, Antarctica. More than 9,000 earthquakes with magnitudes up to 4.6 located SE of Livingston Island were ...detected over a period of 8 months. A few months after the series onset, local seismicity at the nearby (∼35 km) Deception Island volcano increased, displaying enhanced long‐period seismicity and several outbursts of volcano‐tectonic (VT) earthquakes. Before February 2015, VT earthquakes occurred mainly at 5–20 km SW of Deception Island. In mid‐February the numbers and sizes of VT earthquakes escalated, and their locations encompassed the whole volcanic edifice, suggesting a situation of generalized unrest. The activity continued in anomalously high levels at least until May 2015. Given the spatial and temporal coincidence, it is unlikely that the Livingston series and the Deception VT swarm were unrelated. We propose that the Livingston series may have produced a triggering effect on Deception Island volcano. Dynamic stresses associated to the seismic swarm may have induced overpressure in the unstable volcanic system, leading to a magmatic intrusion that may in turn have triggered the VT swarm. Alternatively, both the Livingston earthquakes and the VT swarm could be consequences of a magmatic intrusion at Deception Island. The Livingston series would be an example of precursory distal VT swarm, which seems to be a common feature preceding volcanic eruptions and magma intrusions in long‐dormant volcanoes.
Plain Language Summary
In September 2014 a seismic series occurred near Livingston Island, Bransfield Strait, Antarctica. With 9,000 earthquakes and magnitudes up to 4.6, it is the most numerous swarm ever reported in this region. In February 2015, a volcano‐tectonic swarm took place at Deception Island volcano, a nearby, active volcanic system located 35 km SE. The swarm comprised several hundred earthquakes with magnitudes up to 3.2. The spatial and temporal coincidence of these two events suggests that they could be either cause and effect or consequences of a common process. We propose that the Livingston earthquakes may have induced overpressure in the volcanic system of Deception Island that could trigger the seismic swarm. Alternatively, both swarms could represent the delayed effect of a magmatic intrusion below the volcano. This relationship adds to a growing body of evidence of earthquake‐volcano interactions that must be taken into account in order to properly assess volcanic hazards.
Key Points
We report a seismic swarm in the Bransfield Strait, Antarctica, and subsequent VT activity at Deception Island volcano
The swarm location near Deception Island may have prompted the VT swarm by dynamic triggering of volcanic activity
Alternatively, both the distal and local VT swarms could be a result of a magmatic intrusion at Deception Island
Coverage path planning for spraying drones Vazquez-Carmona, E. Viridiana; Vasquez-Gomez, Juan Irving; Herrera-Lozada, Juan Carlos ...
Computers & industrial engineering,
06/2022, Letnik:
168
Journal Article
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•An efficient coverage path planing algorithm for disinfecting areas is proposed.•The uncertainty of the spraying system is taking into account to improve coverage.•It is possible to ...avoid collisions and maximize the covered area.•The proposed method requires lower computation times.
The pandemic by COVID-19 is causing a devastating effect on the health of the global population. Currently, there are several efforts to prevent the spread of the virus. Among those efforts, cleaning and disinfecting public areas have become important tasks and they should be automated in future smart cities. To contribute in this direction, this paper proposes a coverage path planning method for a spraying drone, an unmanned aerial vehicle that has mounted a sprayer/sprinkler system, that can disinfect areas. State-of-the-art planners consider a camera instead of a sprinkler, in consequence, the expected coverage will differ in running time because the liquid dispersion is different from a camera’s projection model. In addition, current planners assume that the vehicles can fly outside the target region; this assumption can not be satisfied in our problem, because disinfections are performed at low altitudes. Our method presents i) a new sprayer/sprinkler model that fits a more realistic coverage volume to the drop dispersion and ii) a planning method that efficiently restricts the flight to the region of interest avoiding potential collisions in bounded scenes. The algorithm has been tested in several simulation scenes, showing that it is effective and covers more areas with respect to two approaches in the literature. Note that the proposal is not limited to disinfection applications, but can be applied to other ones, such as painting or precision agriculture.
Subdural block and Horner's syndrome Escudero, V; Mihaela Ciorba, I; Viroles Torrent, G ...
Revista española de anestesiología y reanimación,
2014 Aug-Sep, Letnik:
61, Številka:
7
Journal Article
El objetivo del estudio fue evaluar el efecto del bicarbonato de sodio y vitamina C en el comportamiento productivo en pollos Broiler de la línea Cobb-500. Se utilizó un diseño completamente al azar ...(DCA) y se empleó la prueba de Duncan por medio del programa estadístico InfoStat Versión 2008. El estudio duró 6 semanas, se utilizaron 120 pollos de un día de edad con 40 pollos por tratamiento. Se evaluaron 3 tratamientos: control (sin adición), vitamina C en dosis de 5 mg/lt y bicarbonato de sodio en dosis de 48 mg/lt en el agua. No se encontró diferencia significativa entre los tratamientos. El bicarbonato de sodio presento mejores resultados. El mayor consumo de alimento total lo obtuvo el grupo bicarbonato con 168902 g, seguido el control con 164507 g y vitamina C con 163885 g. El mejor peso promedio total lo obtuvo el grupo bicarbonato con 201 g, seguido el control con 2638 g y vitamina C con 2574 g. La ganancia de peso promedio fue mejor para el grupo bicarbonato con 2651 g, seguido el control con 2590 g y vitamina C con 2524 g. La mejor conversión alimenticia lo obtuvo el grupo bicarbonato y control con 1.63 respectivamente, seguido vitamina C con 1.71. Se reporta una mortalidad de 2.5% para el grupo bicarbonato y control respectivamente y 5% para vitamina C. El registro de temperatura y humedad relativa promedio en la galera fue de 28°C y 66% respectivamente.
In cancer research and personalized medicine, new tissue culture models are needed to better predict the response of patients to therapies. With a concern for the small volume of tissue typically ...obtained through a biopsy, we describe a method to reproducibly section live tumor tissue to submillimeter sizes. These micro-dissected tissues (MDTs) share with spheroids the advantages of being easily manipulated on-chip and kept alive for periods extending over one week, while being biologically relevant for numerous assays. At dimensions below ~420 μm in diameter, as suggested by a simple metabolite transport model and confirmed experimentally, continuous perfusion is not required to keep samples alive, considerably simplifying the technical challenges. For the long-term culture of MDTs, we describe a simple microfluidic platform that can reliably trap samples in a low shear stress environment. We report the analysis of MDT viability for eight different types of tissues (four mouse xenografts derived from human cancer cell lines, three from ovarian and prostate cancer patients, and one from a patient with benign prostatic hyperplasia) analyzed by both confocal microscopy and flow cytometry over an 8-day incubation period. Finally, we provide a proof of principle for chemosensitivity testing of human tissue from a cancer patient performed using the described MDT chip method. This technology has the potential to improve treatment success rates by identifying potential responders earlier during the course of treatment and providing opportunities for direct drug testing on patient tissues in early drug development stages.
To compare the machine learning computed tomography (CT) quantification tool, Computer-Aided Lung Informatics for Pathology Evaluation and Ratings (CALIPER) to pulmonary function testing (PFT) in ...assessing idiopathic pulmonary fibrosis (IPF) for patients undergoing treatment and determine the effects of limited (LD) and ultra-low dose (ULD) CT on CALIPER performance.
Thirty-eight IPF patients underwent PFT and standard, LD, and ULD CT. CALIPER classified each CT voxel into either vessel-related structures (VRS), normal, reticular (R), honeycomb (HC) or ground-glass (GG) features. CALIPER-derived interstitial lung disease (ILD) extent represented the sum of GG, R and HC values. Repeated-measures correlation coefficient (ρrm) and 95% confidence interval (CI) evaluated CALIPER features correlation with PFT. Lin's concordance correlation coefficient (CCC) assessed concordance of CALIPER parameters across different CT dosages.
Twenty patients completed 12 months of follow-up. CALIPER ILD correlated significantly with percent predicted (%) forced vital capacity (FVC) and forced expiratory volume in 1 second (%FEV1; p=0.004, ρrm –0.343, 95% CI –0.547, –0.108 and 0.008, –0.321, –0.518, –0.07, respectively). VRS significantly correlated with %FVC and %FEV1 (p=0.000, ρrm –0.491, 95% CI –0.685, –0.251 and –0.478, 0.000, –0.653, –0.231, respectively). There was near perfect LD and moderate ULD concordance with standard dose CT for both ILD (CCC 0.995, 95% CI 0.988–0.999 and 0.9, 0.795–0.983, respectively) and VRS (CCC 0.989, 95% CI 0.963–0.997 and 0.915, 0.806–0.956, respectively).
CALIPER parameters correlate well with PFTs for evaluation of IPF in patients undergoing anti-fibrotic treatment without being influenced by dose variation. CALIPER may serve as a robust, objective adjunct to PFTs in assessing anti-fibrotic treatment related changes.
•Machine learning lung fibrosis quantification is not influenced by CT dose reduction.•Machine learning CT quantification correlates well with pulmonary function.•Such CT quantification may be useful for patients undergoing antifibrotic treatment.
The complete elimination of enzymes from the reaction mixture and the possibility of its recycling for several rounds result in great benefits, allowing the reduction of the enzyme consumption and ...their usability in continuous processes. In this work, it is evaluated the capture of a H6-tagged green fluorescence protein (GFP-H6) on porous magnetic spheres using the Co²⁺ and Ni²⁺ affinity adsorption as a possible cost-effective and up-scaled alternative way for the immobilization of His-tagged proteins. For this purpose, Porous Magnetic Silica (PMS) spheres were synthesized by one-step hydrothermal-assisted modified-Stöber method. The obtained spheres have a homogenous size distribution of 400nm diameter. The γ-Fe₂O₃ nanoparticles are homogenously distributed in the silica matrix. The obtained PMS spheres have a saturation magnetization of about 10emu/g. Magnetophoresis measurements show a total separation time of 16min at 60T/m. The obtained PMS spheres were successfully and homogenously decorated with Co²⁺ and Ni²⁺ and then evaluated for the capture of a GFP-H6 protein. The results were compared with the performance of the commercial beads Dynabeads® His-Tag Isolation & Pulldown.
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