Most of the relevant Big Data processing frameworks (e.g., Apache Hadoop, Apache Spark) only support JVM (Java Virtual Machine) languages by default. In order to support non-JVM languages, ...subprocesses are created and connected to the framework using system pipes. With this technique, the impossibility of managing the data at thread level arises together with an important loss in the performance. To address this problem we introduce Ignis, a new Big Data framework that benefits from an elegant way to create multi-language executors managed through an RPC system. As a consequence, the new system is able to execute natively applications implemented using non-JVM languages. In addition, Ignis allows users to combine in the same application the benefits of implementing each computational task in the best suited programming language without additional overhead. The system runs completely inside Docker containers, isolating the execution environment from the physical machine. A comparison with Apache Spark shows the advantages of our proposal in terms of performance and scalability.
•A new step forward toward the real convergence of HPC and Big Data worlds.•Efficient execution of multi-language applications without additional overhead.•Outperforms Spark considering some of the most typical algorithmic models.•Ignis API inspired by Spark to facilitate the adoption by the research community.•A completely isolated framework running inside Docker containers.
El tumor quístico y papilar del páncreas (TQPP), es una rara entidad, pero que cada vez se describe con más frecuencia. con un comportamiento notoriamente benigno. sin la tendencia a dar metástasis o ...a invadir localmente, características que sí se aprecian en el adenocarcinoma. Este tumor se encuentra más frecuentemente en mujeres jóvenes, y su curso es indoloro en la mayoría de los casos. a pesar de presentarse en forma de grandes masas. En la literatura se han descrito aproximadamente unos 300 casos de esta variedad de tumor, entre ellos también en nuestro medio. En el presente estudio se evaluaron 5 pacientes con TQPP, todos ellos mujeres. entre 24 y 42 años (promedio 29 años). La ubicación en el páncreas se distribuyó así: 1 en la cabeza.2 en el cuerpo y 2 en la cola. El tamaño promedio de estas lesiones fue de 6 x 5 cm y la presentación más frecuente fue la de masa indolora (3 de 5 pacientes). El patrón histológico encontrado describe papilas. así como células epiteliales aisladas con apariencia monomórfica, núcleos esféricos, nucléolos poco prominentes así como áreas con patrones sólidos. trabeculares y/o quísticos. Se practicó 1 pancreatectomía total y 4 pancreatectomías distales. con buena evolución postoperatoria. Como hecho destacable, una de ellas al momento de la cirugía presentaba 18 semanas de gestación (primer caso descrito en la literatura), la cual continuó sin contratiempos. Otra paciente presentaba dos lesiones hepáticas las cuales se extirparon en el mismo acto operatorio y correspondieron a hiperplasia nodular focal. Se enfatiza en estas neoplasias poco comunes, el papel curativo de la cirugía, dado su bajo potencial maligno, lo que se asocia a una baja morbilidad y una larga sobrevida.
In this paper we propose a scalable platform for real-time processing of Social Media data. The platform ingests huge amounts of contents, such as Social Media posts or comments, and can support ...Public Health surveillance tasks. The processing and analytical needs of multiple screening tasks can easily be handled by incorporating user-defined
. The design is modular and supports different processing elements, such as crawlers to extract relevant contents or classifiers to categorise Social Media. We describe here an implementation of a use case built on the platform that monitors Social Media users and detects early signs of depression.
La cartografía geomorfológica permite clasificar el movimiento de ladera de Fonfría como un paleomovimiento paraglaciar, complejo e inactivo, al menos hasta el año 2000, en la fase previa a la ...explotación minera de carbón de Fonfría. Posteriormente, durante la fase de actividad minera y después, el movimiento empieza a ser afectado por estructuras de deformación gravitacional, reactivándose parcialmente.
Introducción. La claritromicina es el antibiótico de primera línea para el tratamiento de la infección por Helicobacter pylori. La resistencia bacteriana se produce principalmente por mutaciones ...puntuales del gen ARN ribosómico 23S (ARNr 23S).Objetivo. Determinar la frecuencia de las mutaciones puntuales A2143G y A2142G del gen ARNr 23S asociadas con la resistencia de H. pylori a la claritromicina en muestras de pacientes con manifestaciones dispépticas en Medellín, región noroccidental de Colombia.Materiales y métodos. Se extrajo ADN a partir de muestras de biopsia gástrica obtenidas de pacientes con manifestaciones dispépticas atendidos en una unidad de endoscopia entre el 2016 y el 2017. Mediante reacción en cadena de la polimerasa (PCR), se amplificaron las regiones s y m del gen vacA y una región del gen ARNr 23S bacteriano. La presencia de las mutaciones A2142G y A2143G se determinó por la técnica de polimorfismos de longitud de fragmentos de restricción (RFLP) con las enzimas BbsI y BsaI, respectivamente.Resultados. Se encontró una prevalencia de infección de 44,2 % (175/396), según el informe de histopatología. En 143 de estas 175 muestras positivas se amplificaron las tres regiones del genoma bacteriano. Se identificaron las mutaciones A2143G y A2142G en 27 muestras (18,8 %; 27/143), la mutación más frecuente fue la A2143G (81,5 %; 22/27).Conclusiones. Hubo una gran prevalencia de mutaciones asociadas con la resistencia de H. pylori a la claritromicina en la población de estudio. Se requieren estudios adicionales para establecer la resistencia bacteriana en la población colombiana y, así, determinar los tratamientos de primera línea y de rescate.
Lameness is a severe welfare problem in cattle and has a detrimental effect on longevity, productivity, and reproductive performance. This study aimed to describe the frequency and distribution of ...foot lesions in cattle using hoof trimming records over a period of 6 years in the Province of Antioquia (Colombia). The data collection instrument enabled differentiation between limbs, digits, and views. The Claw Lesion Identification in Dairy Cattle brochure was the reference for foot lesion identification. A total of 1814 foot lesions observations, recorded from 1120 cows in 71 herds, were analyzed and 11 different foot lesions were identified. Non-infectious foot lesions were more common than infectious (94.4 vs 5.6%). White line disease was more frequently observed in the hind limbs (79.6%) compared to the front limbs (20.4%), and more frequent in medial claws of the front limbs (70.3%) compared to lateral claws (29.7%). In hind limbs, the lateral claws were more commonly affected (65.7%) compared to the medial claws (34.3%). Claw zone 3 was affected in 61.3% of the cases, followed by zones 2 (21.7%) and 1 (17%). Although our data are from a limited area of the country, they are consistent with published and anecdotal reports of foot lesions in cattle in Colombia and worldwide. Our results suggest that there is need for additional prospective research under Colombian dairy cattle management conditions to better understand the lameness and benefit of trimming intervention.
Political bots, through astroturfing and other strategies, have become important players in recent elections in several countries. This study aims to provide researchers and the citizenry with the ...necessary knowledge to design strategies to identify bots and counteract what international organizations have deemed bots’ harmful effects on democracy and, simultaneously, improve automatic detection of them. This study is based on two innovative methodological approaches: (1) dealing with bots using hybrid intelligence (HI), a multidisciplinary perspective that combines artificial intelligence (AI), natural language processing, political science, and communication science, and (2) applying framing theory to political bots. This paper contributes to the literature in the field by (a) applying framing to the analysis of political bots, (b) defining characteristics to identify signs of automation in Spanish, (c) building a Spanish-language bot database, (d) developing a specific classifier for Spanish-language accounts, (e) using HI to detect bots, and (f) developing tools that enable the everyday citizen to identify political bots through framing.
Introducción. El pilar fundamental del tratamiento del cáncer colorrectal es la cirugía, situación que expone a los pacientes a la posible presentación de complicaciones, morbimortalidad, pobre ...calidad de vida, recurrencia tumoral o la muerte. El objetivo de este estudio fue determinar las variables clínicas y quirúrgicas que inciden en el riesgo de la aparición de complicaciones en los pacientes con cáncer colorrectal llevados a cirugía electiva entre los años 2016 y 2019.
Métodos. Estudio observacional, descriptivo, transversal y retrospectivo. Se incluyeron pacientes mayores de 18 años con cáncer colorrectal sometidos a cirugía electiva. Se realizó un análisis multivariado para determinar los factores que se relacionan con las complicaciones postquirúrgicas.
Resultados. Se incluyeron 298 pacientes, 68 % mayores de 60 años, 52,3 % mujeres, 74,2 % presentaban comorbilidades y 48,3 % fueron diagnosticados en estadio III. El 48,3 % presentó complicaciones postoperatorias. De ellos, el 68,1 % no tenía tamización nutricional y el 61,8 % no tenía preparación del colon; un 55 % fueron cirugías del recto, 69,1 % de las cirugías fueron por vía laparoscópica y 71,8 % presentaron sangrado inferior a 500 ml. La mayoría de las complicaciones fueron clasificadas como Clavien-Dindo I-III.
Discusión. Las características de los pacientes fueron similares a los presentados en otros estudios, aunque hubo mayor incidencia de íleo postoperatorio. El análisis multivariado mostró una mayor probabilidad de presentar una complicación en pacientes con diabetes mellitus, hipertensión arterial, falta de tamización nutricional o preparación de colon, cirugía de recto y el sangrado mayor a 500 ml.
The 2015 Paris Agreement was adopted at the twenty-first session of the Conference of the Parties (COP 21) to the United Nations Framework Convention on Climate Change (UNFCCC). In the run-up to COP ...21, most UNFCCC Parties put forward intended nationally determined contributions (INDCs), containing mitigation pledges. These INDCs are now being confirmed as nationally determined contributions (NDCs), as governments formally ratify the Paris Agreement. NDCs are supposed to provide transparent, quantifiable, comparable, and verifiable mitigation objectives. However, there is neither methodological nor data consistency in the way Parties have prepared their NDCs. This article showcases recent collaboration among research, government, and private institutions that contributed to the Colombian NDC. While documenting the novel research, data, and rich web of collaboration that helped the Colombian government prepare the country's NDC, this article links this specific case with the challenges of policy-oriented and interactive models of research. Our experience confirms previous research on the importance of stakeholder interaction, transparency and openness of processes, and willingness to break disciplinary and institutional barriers. In addition, the experience points to the importance of having appropriate available resources and a local institution acting as champion for the project.
POLICY RELEVANCE
The lack of methodological and data consistency in the way parties have prepared their nationally determined contributions (NDCs) can significantly slow down the progress toward limiting global warming below 2 °C above pre-industrial levels. In the meantime, calls for scientists to provide 'usable' information are increasing and the importance of close collaboration between scientists, end-users, and stakeholders is also increasingly acknowledged. In this article we make explicit the process and research challenges faced during what was, in the authors' opinion, the successful collaboration among scientists, governmental, and private institutions that led to the formulation of an essential component of the Colombian NDC. As policy makers move forward with the implementation of their plans and as scientists become increasingly engaged with government planning, it is essential that they are aware of the needs and demands in terms of collaborations, data, resources, and type of results necessary to produce analyses that can be made fully public and can withstand international scrutiny.
Proctocolectomy with ileal reservoir is the surgical procedure of choice for patients with ulcerative colitis and familial adenomatous polyposis.
To evaluate long-term postoperative complications ...(1994-2019) in patients operated for familial adenomatous polyposis (FAP) and ulcerative colitis (UC) and the degree of satisfaction with the procedure.
Observational study based on the analysis of a retrospective database with prospective follow-up in 115 consecutive patients: 79 with UC and 36 with FAP. A total of 88 patients were followed up, 60 with UC and 28 with PFA.
48 males (54.4%) with a mean age of 44.8 ± 10.6 years were evaluated. Indications for surgery were intractable disease in 54 patients (47%), dysplasia/cancer in 43 (37%), severe bleeding in 4 (4%) and perforation in 3 (3%). A proctectomy and mucosectomy of the rectal stump was performed in 67 (76.1%), and a double stapling technique in 21. A protective ileostomy was performed in all patients with UC and FAP. No differences were found in early complications between the two groups. Late complications showed a higher rate of reservoritis in UC patients compared to FAP (44.9 vs. 14.3%, p = 0.001), with more refractory reservoritis in the UC group (13.3 vs. 0%, p = 0.04) with no differences in bowel obstruction, strictures, or anastomotic fistulas. Overall satisfaction and adaptation were considered good in 87% of UC patients and only 57% in the FAP group (p < 0.01).
Proctocolectomy with ileal reservoir has comparable morbidity and mortality, except for the higher rate of reservoritis in patients with a history of UC, despite this contingency there is a better quality of life and greater acceptance of surgery in UC patients than in FAP patients.
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