We report detailed investigations of the properties of a superconductor obtained by substituting In at the Sn site in the topological crystalline insulator (TCI), SnTe. Transport, magnetization, and ...heat capacity measurements have been performed on crystals of Sn sub(0.6)In sub(0.4) Te, which is shown to be a bulk superconductor with (ProQuest: Formulae and/or non-USASCII text omitted) at ~4.70(5) K and (ProQuest: Formulae and/or non-USASCII text omitted) at ~3.50(5) K. The upper and lower critical fields are estimated to be mu sub(0)Hc2 (0) = 1.42 (3) T and mu sub(0)Hc1 (0) = 0.90 (3) mT, respectively, while Kappa = 56.4(8) indicates this material is a strongly type-II superconductor.
Highlights • New information on, and quantification of, the effect of impedance differences on the spatial distribution of sensitivity for tetrapolar impedance measurements. • Key design principles, ...implementation and validation of a physical system for measuring the spatial distribution of transfer impedance. • Application and interpretation of the findings to skin surface tetrapolar impedance measurements.
<img src=” https://s3.amazonaws.com/production.scholastica/article/17956/medium/prnano_562020_ga.jpg?1605542414”> Cancer is a group of diseases characterized by the uncontrolled growth of cells. ...These cells in-vade organs and tissues by extension or direct dissemination and can spread to other regions of the body. Nanomedicine offers many possibilities to prevent the spread of cancer tissue and help cure the disease. In this work, solid lipid nanoparticles (SLN) were used to encapsulate perillyl alcohol (PA), a volatile monoterpene with proven anticancer activity. Encapsulation of PA into SLN (SLN-PA) is expected to promote controlled release, increase PA bioavailability, and impair the volatility of the monoterpene. SLN-PA prepared by high-shear homogenization showed average particle diameter around 254 nm, polydispersity index ~ 0.35, zeta potential ~ -14.7 mV, and encapsulation efficiency 84.6%. Scanning electron microscope analysis revealed a decrease in crystallinity, suggesting the encapsulation of PA in the SLN, confirming the spherical shape and the loading of the monoterpene in the SLN. In vitro cytotoxicity assays against murine fibroblasts (L929) showed that SLN-PA in both treated doses did not induce any cytotoxicity on non-tumoral cells. In vivo antitumor effect of the SLN-PA was evaluated in sarcoma 180-transplanted mice. The in vivo results demonstrated a significant tumor inhibition rate of 51.76 and 54.49% via intraperitoneal application of SLN-PA at doses of 100 and 200 mg/kg/day (p < 0.05), respective when compared to the nega-tive control (dimethyl sulfoxide). Adverse side effects of SLN-PA were not noticed in the liver, the kidney, or spleen tissue. The developed SLN-PA can be considered as a safe approach for site-specific antitumor effect in vivo, reinterpreting new nanoparticles-based cancer therapy.
The new UK Foundation Programme is competency based, with a trainee’s progression dependent on achieving and demonstrating a range of competencies. However, we do not know whether all rotations, ...comprising different combinations of specialties, will enable the foundation programme trainees to acquire these competencies. Questionnaires were sent to 100 consultants from a range of specialties asking them to predict if a foundation year 1 or foundation year 2 doctor could acquire each competency when working in the consultant’s specialty. Views on the competency framework as a whole were also sought. Results suggest that the competencies trainees may acquire depend on the specialties they experience in their rotation. Moreover, a range of competencies may prove difficult to acquire across most of the specialties. This has implications for the composition of foundation programme rotations, for educational and clinical supervision, and for the content and mode of curriculum delivery.
The following summary presents the key findings of an evaluation of a 6 month trial of one Integrated Learning System (ILS) in nine U.K. Schools, conducted by the School of Education, Leicester ...University. The pupils in the target population ranged from 8 to 13 years of age. The evaluation design was based on the comparison of outcome performance in mathematics (basic numeracy) and reading for designated experimental and control groups in five schools, although additional data from all nine schools enriched this central core of data. In addition the evaluators monitored pupil behaviour. There were significant learning gains in the ILS treatment group for mathematics (basic numeracy) compared to the Control group. However, no such gains were recorded for reading. There were no discernible differences in patterns of attendance at school for ILS and Control groups. In general, behaviour was good when using the ILS with higher time on task and a calmer working atmosphere than in the standard classroom. There was some indication that this improved behaviour transferred to the standard classroom over time.
The global pandemic has delayed many real estate plans while accelerating the adoption of many technology challenges. In turn, these technologies will disrupt the real estate industry, causing some ...to become irrelevant and useless. Combined with the increasing numbers of ageing baby boomers, what is Singapore's future going to look like? What plans should we make for our properties? Market commentator and respected real-estate expert Ku Swee Yong weighs in on some of these questions and shares his insights on the opportunities for investors and what is the future of real estate in Singapore.
History is more than facts and figures, people and places, wars and politics, deaths and disasters. Stories are never fixed in stone; they continue to morph and evolve with every retelling. Author ...Simon Maier casts himself in the role of a hotelier who has worked in different cities around the world over the last 60 years. Wry, witty and sharp, history is told through a refreshing point of view. As the narrator chronicles key events of the 20th and 21st centuries, he provides details of the atmosphere, and recounts tales from people on the ground, along with sketches of the mood and beliefs of the time. Such details infuse the biggest and most important occasions of modern times with insight, precision and warmth. This book is a fascinating mix of fact and fiction; of what did happen and what might have happened. History is scattered with many great changes; some planned, most sudden; some shocking, others happy. We see the front view of the occasion, the announcement, the television footage, the moment in lights. We see the stage that is put before us - but what about behind the scenes? What insights can we find on the other side of history?.
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