The first implementation of NASA’s Total and Spectral Solar Irradiance Sensor (TSIS-1) launched on December 15th, 2017, and was integrated into the International Space Station (ISS) to measure both ...the total solar irradiance (TSI) and the solar spectral irradiance (SSI). The direct measurement of the SSI is made by the LASP Spectral Irradiance Monitor (SIM) and provides data essential to interpreting how the Earth system responds to solar spectral variability. Extensive advances in TSIS-1 SIM instrument design and new SI -traceable spectral irradiance calibration techniques have resulted in improved absolute accuracy with uncertainties of less than 0.5% over the continuous 200–2400 nm spectral range. Furthermore, improvements in the long-term spectral stability corrections provide lower trend uncertainties in SSI variability measurements. Here we present the early results of the TSIS-1 SIM measurements covering the first 5 years of operations. This time period includes the descending phase of solar cycle 24, the last solar minimum, and the ascending phase of solar cycle 25. The TSIS-1 SIM SSI results are compared to previous measurements both in the absolute scale of the solar spectrum and the time dependence of the SSI variability. The TSIS-1 SIM SSI spectrum shows lower IR irradiance (up to 6% at 2400 nm) and small visible increases (~0.5%) from some previous reference solar spectra. Finally, initial comparisons are made to current NRLSSI2 and SATIRE-S SSI model results and offer opportunities to validate model details both for short-term (solar rotation) spectral variability and, for the first time, the longer-term (near half solar cycle) spectral variability across the solar spectrum from the UV to the IR.
Degradation Correction of TSIS SIM Mauceri, Steffen; Richard, Erik; Pilewskie, Peter ...
Solar physics,
11/2020, Letnik:
295, Številka:
11
Journal Article
Recenzirano
An understanding of solar variability over a broad spectral range and broad range of timescales is needed by scientists studying Earth’s climate. The Total and Spectral Solar Irradiance Sensor (TSIS) ...Spectral Irradiance Monitor (SIM), is designed to measure solar spectral irradiance (SSI) with unprecedented accuracy from 200 nm to 2400 nm. SIM started daily observations in March 2018. To maintain its accuracy over the course of its anticipated 5-year mission and beyond, TSIS SIM needs to be corrected for optical degradation, common for solar viewing instruments. The differing long-term trends of various independent solar-irradiance records attest to the challenge at hand.
The correction of TSIS SIM for optical degradation is based on piecewise linear fits that bring the three instrument channels into agreement. It is fundamentally different to the correction applied to the TSIS SIM predecessor on SORCE. The correction facilitates reproducibility, uncertainty estimation and is measurement-based. Corrected, integrated TSIS SIM SSI agrees with independent observations of total solar irradiance to within 45 ppm as well as various solar-irradiance models. TSIS SIM SSI is available at:
http://lasp.colorado.edu/lisird/
.
A 19-month-old girl with trisomy 21 and a congenitally bicuspid aortic valve died following a short febrile illness. Autopsy disclosed pericarditis, epimyocardial abscess, infective endocarditis, and ...a sinus of Valsalva aneurysm. Microscopy demonstrated continuity between the aortic wall and valve leaflet, consistent with an acquired aneurysm. Abnormal hemodynamics associated with the valve malformation likely facilitated endocarditis.
The Colorado Ultraviolet Transit Experiment (CUTE) is a 6U NASA CubeSat carrying on-board a low-resolution, near-ultraviolet (2479-3306 A) spectrograph. It has a Cassegrain telescope with a ...rectangular primary to maximize the collecting area, given the shape of the satellite bus, and an aberration correcting grating to improve the image quality, and thus spectral resolution. CUTE, launched on the 27th of September 2021 to a Low Earth Orbit, is designed to monitor transiting extra-solar planets orbiting bright, nearby stars to improve our understanding of planet atmospheric escape and star-planet interaction processes. We present here the CUTE autONomous daTa ReductiOn pipeLine (CONTROL), developed for reducing CUTE data. The pipeline has been structured with a modular approach, which also considers scalability and adaptability to other missions carrying on-board a long-slit spectrograph. The CUTE data simulator has been used to generate synthetic observations used for developing and testing the pipeline functionalities. The pipeline has been tested and updated employing ight data obtained during commissioning and initial science operations of the mission.
We report two cases of unexpected death due to metastatic gestational choriocarcinoma and provide a review of the literature regarding these neoplasms. Our cases illustrate the extreme importance of ...medical follow-up of patients after an ectopic pregnancy or therapeutic abortion.
We have identified a previously unrecognized source of accidental drowning in infants and toddlers: 5-gal (19-L) industrial buckets. Twelve cases of drownings in these large-capacity buckets ...constituted 24% of all infant and toddler (age less than 3 years) drownings investigated by the Cook County (Illinois) Medical Examiner's Office from January 1985 to June 1989. The buckets, all with 5-gal and 18-kg capacity, are constructed of heavy, rigid plastic and are intended for industrial use. Home use, typically as mop buckets, was associated with the toddlers' death. The large size and heavy construction of these buckets as well as the toddlers' cephalad center of gravity and undeveloped coordination prohibit the toddlers from extricating themselves after peering into and falling inside the buckets. Parents and public health officials should be advised that domestic use of these containers poses a serious threat to the safety of curious toddlers. Adults should never leave toddlers unattended around even small amounts of water.
Air pollution measurements collected through systematic mobile monitoring campaigns can provide outdoor concentration data at high spatial resolution. We explore approaches to minimize data ...requirements for mapping a city’s air quality using mobile monitors with “data-only” versus predictive modeling approaches. We equipped two Google Street View cars with 1-Hz instruments to collect nitric oxide (NO) and black carbon (BC) measurements in Oakland, CA. We explore two strategies for efficiently mapping spatial air quality patterns through Monte Carlo analyses. First, we explore a “data-only” approach where we attempt to minimize the number of repeated visits needed to reliably estimate concentrations for all roads. Second, we combine our data with a land use regression-kriging (LUR-K) model to predict at unobserved locations; here, measurements from only a subset of roads or repeat visits are considered. Although LUR-K models did not capture the full variability of on-road concentrations, models trained with minimal data consistently captured important covariates and general spatial air pollution trends, with cross-validation R 2 for log-transformed NO and BC of 0.65 and 0.43. Data-only mapping performed poorly with few (1–2) repeated drives but obtained better cross-validation R 2 than the LUR-K approach within 4 to 8 repeated drive days per road segment.
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The study endeavors the fabrication of extended-release adipic acid (APA) buccal films employing a quality by design (QbD) approach. The films intended for the treatment of xerostomia ...were developed utilizing hot-melt extrusion technology. The patient-centered quality target product profile was created, and the critical quality attributes were identified accordingly. Three early-stage formulation development trials, complemented by risk assessment aligned the formulation and process parameters with the product quality standards. Employing a D-optimal mixture design, the formulations were systematically optimized by evaluating three formulation variables: amount of the release-controlling polymer Eudragit® (E RSPO), bioadhesive agent Carbopol® (CBP 971P), and pore forming agent polyethylene glycol (PEG 1500) as independent variables, and % APA release in 1, 4 and 8 h as responses. Using design of experiment software (Design-Expert®), a total of 16 experimental runs were computed and extruded using a Thermofisher ScientificTM twin screw extruder. All films exhibited acceptable content uniformity and extended-release profiles with the potential for releasing APA for at least 8 h. Films containing 30% E RSPO, 10% CBP 971P, and 20% PEG 1500 released 88.6% APA in 8 h. Increasing the CBP concentration enhanced adhesiveness and swelling capacities while decreasing E RSPO concentration yielded films with higher mechanical strength. The release kinetics fitted well into Higuchi and Krosmeyer-Peppas models indicating a Fickian diffusion release mechanism.
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