OBJECTIVE: to compare the immediate and long-term results of endoscopic mucosal resection with a circular incision (C-EMR) and endoscopic submucosal dissection (ESD) in the treatment of patients with ...large benign epithelial neoplasms of the colon. PATIENTS AND METHODS: a prospective randomized comparative study was conducted from November 2020 to July 2022, included 103 patients with benign epithelial neoplasms of the colon ranging in size from 20 to 30 mm. The C-EMR method was used in 52, ESD - 51 patients. RESULTS: the removal of the tumor by the C-EMR method required statistically significantly less time, compared with the ESD method – 30 and 60 minutes, respectively (p<0.001). Intra- and postoperative complications occurred in 13(23.7%) patients in the C-EMR group and in 12(23.5%) patients in the ESD group. The most frequently reported complication was postcoagulation syndrome in the main and control groups – in 9(17.3%) and 11(21.6%) cases, respectively. It was found that the difficult location of the tumor (OR=18.3; p=0.01) and intraoperative complications (OR =37.5; p=0.04) are independent conversion factors of endoscopic intervention. The frequency of tumor removal in a en bloc and achievement of negative resection margins (R0) in the main and control groups did not significantly differ – 47(90.4%) and 49(96.1%) (p=0.4) and 40(76.9%) and 45(88.2%) (p=0.2), respectively. CONCLUSION: endoscopic mucosal resection with a circumferential incision is an effective and safe operation comparable to endoscopic submucosal dissection, and can be the method of choice for benign epithelial neoplasms of the colon with sizes from 20 to 30 mm. In addition, the duration of the operation using the C-EMR method is two times less than using ESD.
Virtual reality (VR) is widely used for medical purposes, particularly, for assessment and treatment of phobic anxiety disorders. The article provides a review and critical analysis of methods and ...tools for assessing phobic anxiety disorders via registration and digital processing of physiological signals, and adaptation of various VR scenes to the user's actual state. The article presents a technique for studying phobic anxiety disorders in VR environment that enables VR scenes to be adapted for a particular user, considering his individual features, and behavior parameters. Adaptation of VR scenes is carried out by selecting an optimal set of hidden signal patterns registered with electrocardiogram and electroencephalogram signals.
AIM:
to assess the early results in patients with benign epithelial colorectal neoplasms which underwent endoscopic mucosal resection with a circumferential incision (C-EMR).
PATIENTS AND METHODS:
a ...prospective randomized trial included 50 patients who underwent endoscopic removal of benign epithelial colorectal neoplasms sized 20–30 mm (November 2020 — January 2022). The main group included 26 patients which underwent C-EMR. The control group included 24 patients which underwent endoscopic submucosal dissection (ESD).
RESULTS:
postoperative complications developed in the C-EMR group in 5 (19.2%), and in the ESD group — in 7 (29.2%) cases (p = 0.51). The operative time in the C-EMR group was significantly less than in the ESD group — 30 vs 60 min., respectively (p < 0.001). In all cases in both groups, tumors were removed en bloc. There R0 resection were performed in 22 (84.6%) and in 23 (95.8%) cases in the main and control groups, respectively (p = 0.3). Two (8.3%) procedures in the control group were converted to the C-EMR procedure.
CONCLUSION:
endoscopic mucosal resection with a circumferential incision is an effective and safe method for removing benign epithelial neoplasms sized 20–30 mm, as well as submucosal dissection. The removal of the tumor by the C-EMR method reduces operative time by half compared with ESD method.
Aim:
to identify the risk factors for conversion of endoscopic submucosal dissection to abdominal surgery.
Patients and methods
: the prospective cohort study included 405 patients: 166 (40.9%) males ...and 239 (59.1%) females. The median age was 66 (59; 72) years old; the patients underwent endoscopic submucosal dissection of colorectal epithelial neoplasms.
Results:
the median size of the removed neoplasms was 3.0 (2.4; 4) cm, tumor was removed en bloc in 324/363 (89.2%) cases; and R0 resection margins were detected in 218/324 (67.3%) cases. Significant risk factors for conversion were: the tumor size ≥ 3.2 cm (OR 2.9, 95% CI 1.2–7.1, p = 0.017), lifting ≤ 3 mm (OR 41, 95% CI 15–105, p = 0.000002) and the tumor vascular pattern IIIa according Sano’s capillary pattern classification (OR 4.0, 95% CI 1.3–11.9, p = 0.013).
Conclusion:
endoscopic submucosal dissection is a safe way to remove colorectal neoplasms. However, the presence of conversion risk factors can influence the outcome of endoscopic treatment.
Rapid progress in organic electronics demands new highly efficient organic semiconducting materials. Nevertheless, only few materials have been created so far that show reliable band-like transport ...with high charge mobilities, which reflects the two main obstacles in the field: the poor understanding of charge transport in organic semiconductors (OSs) and the difficulty of its quantification in devices. Here, we present a spectroscopic method for assessment of the charge transport in organic semiconductors. We show that the intensities of the low-frequency Raman spectrum allow calculation of the dynamic disorder that limits the charge carrier mobility. The spectroscopically evaluated mobility clearly correlates with the device charge mobility reported for various OSs. The proposed spectroscopic method can serve as a powerful tool for a focused search of new materials and highlights the disorder bottleneck in the intrinsic charge transport in high-mobility organic semiconductors.
Some applications of dense gas discharge with runaway electrons Maltsev, A.N.; Sankevich, D.A.; Shapareva, O.G. ...
The 31st IEEE International Conference on Plasma Science, 2004. ICOPS 2004. IEEE Conference Record - Abstracts,
2004
Conference Proceeding
Summary form only given. Applications of the runaway electron discharge in air under normal conditions are given in the report for the following areas. 1. Sterilization of air and other gaseous ...objects. 2. Radiation-plasma processing of food products (on an example of cereals processing). 3. Sterilization of medical toolsand a dressing material. 4. Roentgenography, defectoscopy, and safety systems on a basis of the air discharge X-ray radiation. 5. Luminescence analysis of minerals and other kinds of the condensed media. 6. Optical fiber and other solid state sources of a dense UV and violet radiation. 7. Excitation of dense gas lasers. 8. Excitation of vibronic crystal lasers. For each of the specified areas of applications the experimental data showing high efficiency, simplicity, reliability and small cost price of the appropriate technology are resulted.