Anthropometric characteristics, physical fitness and technical skills of under-19 (U19) soccer players were compared by competitive level (elite, n=95; non-elite, n=85) and playing position ...(goalkeeper, central defender, fullback, midfield, forward). Fitness tests included 5- and 30-m sprints, agility, squat jump (SJ) and countermovement jump (CMJ), strength and Yo-Yo intermittent endurance test level 2 (Yo-Yo IE2). Soccer-specific skills included ball control and dribbling. Independent of position, elite players presented more hours of training per year than non-elite players (d>1.2). Stature and body mass discriminated elite from non-elite players among goalkeepers and central defenders (d>0.6). Major differences were noted between elite and non-elite goalkeepers for SJ, CMJ, Yo-Yo IE2, and ball control (d>1.2). Elite central defenders performed better than their non-elite counterparts in SJ and ball control tests (d>1.2). Elite players presented better agility and Yo-Yo IE2 performances than non-elite players within all positional roles (d>0.6). In conclusion, U19 players differed in anthropometric characteristics, physical fitness and technical skills by competitive level within field positions.
In young athletes, demands of sports are superimposed on normal growth and maturation. It has been suggested that this causes a temporarily increased vulnerability for injuries. We followed 26 ...talented soccer players (mean age 11.9±0.84 years) longitudinally for 3 years around their adolescent growth spurt, called Peak Height Velocity, to identify differences in number of traumatic and overuse injuries and days missed due to injuries. Peak Height Velocity was calculated according to the Maturity Offset Protocol. The number of injuries was calculated for each player per year. A repeated measurement analysis showed that athletes had significantly more traumatic injuries in the year of Peak Height Velocity (1.41) than in the year before Peak Height Velocity (0.81). A moderate effect size of 0.42 was found for the difference in number of overuse injuries per player per year before (0.81) and after Peak Height Velocity (1.41), respectively. Finally, a moderate effect size of 0.55 was found for difference between days missed due to injuries before (7.27 days per player per year) and during Peak Height Velocity (15.69 days per player per year). Adolescent growth spurt seems to result in increased vulnerability for traumatic injuries. Afterwards athletes seem to be susceptible to overuse injuries.
The present study determined to what extent the variance in performance might be explained by chronological age, biological maturation, training load and anthropometry in 168 Belgian male handball ...players aged 14 years: anthropometric, strength, speed and sport-specific skills were assessed. MANOVA tested the effect of chronological age and biological maturity, whereas MANCOVA was used to compare maturity groups controlling for chronological age and training load. In addition, canonical correlation analysis was used between age, maturity-offset and anthropometry, on one side, and performance and sport-specific skills, on the other side. Results revealed significant differences between early, on-time and late maturity groups for anthropometry (p<0.001), strength (p<0.001) and sprint 20-m (p<0.05) in favour of the early maturing players. The difference between the mean values of the extreme groups for height was 24.8 cm, for weight 33.2 kg and, for body fat 6.5%; for handgrip 20.2 kg, for 5-jump test 1.1 m and for 20-m sprint 0.20 s. Maturity status had no effect on sport-specific skills. Canonical correlations indicated that poorer scores in sport-specific skills were related to fatness and lack of training. In parallel, a substantial relationship was found between early maturity-offset, body size, strength and 20-m sprint.
Adolescence is often viewed as a critical period for selection in youth soccer. The present study compared the characteristics of regionally selected and non-selected under-14 players (U-14) as a ...group and by position. Players were classified as local (n=69) and regional (n=45). Weight, height, skinfolds, functional capacities, soccer skills and goal orientation were measured and skeletal age was assessed with the Fels method. Factorial ANOVA was used to test the effect of selection, position and respective interaction terms, while discriminant analysis was used to identify the variables that contributed to selection. Selected players had an advanced maturity status (F=24.97, p<0.01), were heavier (F=30.67, p<0.01) and taller (F=35.07, p<0.01); performed better in explosive power (F=21.25, p<0.01), repeated sprints (F=20.04, p<0.01) and ball control (F=3.69, p<0.05); and were more ego oriented (F=13.29, p<0.01). The 2 competitive groups did not differ in agility, aerobic endurance, dribbling, shooting, passing, and task orientation. Position-related variation was negligible. The percentage of players who were correctly classified in the original groups was slightly lower when the analysis was performed for the total sample (86%) than by position (86-90%). Future research on talent identification and selection should adopt a multidimensional approach including variables related to the physiological, perceptual, cognitive and tactical demands.
Predictors of functional capacities and skills in 143 soccer players aged 11–14 years from five clubs in Portugal were investigated. Data for players aged 11–12 (n=75) and 13–14 (n=68) years included ...chronological age, skeletal age, stage of pubic hair (PH), anthropometry, four functional capacities, four soccer skills and experience; composite functional and skill scores were derived. Multiple linear regression analysis was used to examine the independent effects of age, maturity, body size and proportions, adiposity and experience on individual functional capacities and skills and composite scores. Explained variances differed among functional capacities (22–48%) and skills (<25%), and were greater for composite functional (younger 37%, older 58%) than skill (younger 26%, older 18%) scores. Skeletal maturity was a predictor of the counter‐movement jump in both groups and of composite functional and skill scores in older players. Age and adiposity were primary predictors in players aged 11–12 years, while experience and a proportionally longer trunk (conversely, relatively shorter lower extremities) appeared among predictors in players aged 13–14 years. PH was not among predictors. Except for the counter‐movement jump, predictors of functional capacities and soccer skills differed between age groups.
Available data on the associations between motor competence (MC) and flexibility are limited and result inconclusive. This study aims to examine the relationship between flexibility and MC in ...children. The sample comprised 596 Portuguese children (47.1% girls) aged 9.7 ± 0.6 years. Motor competence was evaluated with the body coordination test, Körperkoordination Test für Kinder. Cardiorespiratory fitness (20‐m shuttle run), muscular strength (curl‐up and push‐up tests), and flexibility (back‐saver sit and reach and trunk‐lift tests) were evaluated using the Fitnessgram Test Battery. Z‐scores by age and gender for the physical fitness tests were constructed. Analysis of variance and regression analysis were performed. Participants in the healthy zone groups of both flexibility tests exhibited significantly better scores of MC than the participants under the healthy zone (P < 0.001). Back‐saver sit and reach and trunk‐lift Z‐scores, either individually or as a sum, were significant predictors of MC (P < 0.05 for all) after adjustments for the other physical fitness components, age, body mass index, and socioeconomic status, in both genders. Our findings highlight the importance of promoting and developing flexibility, as well as the other health‐related physical fitness components in schoolchildren to reach adequate levels of MC.
This study compared variation in size, function and sport-specific technical skills of youth soccer players associated with differences in biological maturity status. 60 male soccer players of ...under-14 (U14) and under-17 (U17) categories were submitted to anthropometric and body composition measurements as well as motor and soccer-specific technical skill tests. Skeletal maturity was determined by skeletal age. Athletes of both categories were classified as early, on-time or late-maturing, according to the difference between chronological age and skeletal age. Body mass and height were lower in the late athletes, independent of category (P<0.01). Differences in adiposity were found only between athletes of the U14 (late<early, P<0.05). Statistically significant differences were identified on aerobic endurance in U14 (early<on time, P<0.01), upper limbs muscular strength (late<early, P<0.01) and flexibility in U17 (late<on time, P<0.05). Players in each age group of contrasting maturity status do not differ in soccer-specific skills. The results suggest that the maturational development influences body mass, height, body fat, flexibility, muscular strength of upper limbs and cardiorespiratory fitness, whereas the specific technical skills and other functional capabilities do not seem to be affected.
This study retrospectively analyzed the risk factors for oral mucositis (OM) during cetuximab treatment.
We screened patients using cetuximab and retrospectively evaluated the presence of OM based on ...medical records. We collected information from 2 years of evaluations. Patient medical records were reviewed to obtain data on chemotherapy cycle and dose, sex, age, primary tumor, TNM stage, and head and neck radiotherapy (HNR) history. The X2 test and multinomial logistic regression were used for statistical analysis (SPSS 20.0, p < 0.05).
Among 1831 patients, OM was showed in 750 in any grade (41%), during cetuximab treatment. Most patients were female (n=944, 51.6%), <70years-old (n=1149, 62.8%), had larynx cancer (n=789, 43.1%) in T4 (n=579, 47.7%), N0 (n=509, 52.6%) stages. Primary tumor surgery was performed in 1476 (80.6%) patients, radiotherapy in 606 (33.1%) patients and cetuximab protocols most used involved up to four cycles (n=1072, 58.5%) of <400mg (n=996, 54.4%) cetuximab doses. Female (OR odds ratio = 2.17, CI95% = 1.26-3.75), >70 years-old patients (OR = 16.02, CI95% = 11.99-21.41), with HHNR (OR = 1.84, 1.41-2.40), treated with >4 cycles (OR = 1.52, CI95% = 1.16-2.01) and high doses of cetuximab (OR = 3.80, CI95% = 2.52-5.71) are the greatest risk factors for OM.
Since the clinical benefit of cetuximab in the treatment of older patients is limited and there is a high OM, especially in women with head and neck treated with radiotherapy, high doses and a high number of cetuximab cycles must be administered with caution.
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Several active compounds are sensitive to light, especially to the ultraviolet radiation (UV-R) leading to their degradation or modification, with lost or decrease of their biological ...activity. The aim of this study was to perform a systematic review regarding photostabilization strategies used on health products and perform a critical appraisal of their effectiveness.
The bibliographic search identified 2261 results and merely 40 studies met the selection criteria. Of these, 85% referred to encapsulation strategies, 10% to antioxidants and 5% to the use of solar filters. Cyclodextrins (CD’s) were the most used encapsulation systems (32.5%) followed by liposomes and lipid nanoparticles (each 17.5%), microparticles (15%) and polymeric nanoparticles (10%). The most effective were found to be liposomes and lipid nanoparticles. However, the different methodological conditions used limit the true relevance of this finding.
A gold standard strategy suitable for all compounds cannot be proposed. Instead, case-by-case evaluation, supported on the photodegradation mechanism is recommended. Systematic studies that compare different photostabilization strategies undertaken with the same irradiation conditions are also needed.
The contribution of chronological age, skeletal age (Fels method) and body size to variance in peak velocity derived from the Carminatti Test was examined in 3 competitive age groups of Brazilian ...male soccer players: 10-11 years (U-12, n=15), 12-13 years (U-14, n=54) and 14-15 years (U-16, n=23). Body size and soccer-specific aerobic fitness were measured. Body composition was predicted from skinfolds. Analysis of variance and covariance (controlling for chronological age) were used to compare soccer players by age group and by skeletal maturity status within of each age group, respectively. Relative skeletal age (skeletal age minus chronological age), body size, estimated fat-free mass and performance on the Carminatti Test increased significantly with age. Carminatti Test performance did not differ among players of contrasting skeletal maturity status in the 3 age groups. Results of multiple linear regressions indicated fat mass (negative) and chronological age (positive) were significant predictors of peak velocity derived from the Carminatti Test, whereas skeletal age was not a significant predictor. In conclusion, the Carminatti Test appears to be a potentially interesting field protocol to assess intermittent endurance running capacity in youth soccer programs since it is independent of biological maturity status.