The book provides a detailed and practical description of how companies can put purpose into practice in their organizations. Based on a ground-breaking research project on the Economics of Mutuality ...undertaken jointly by the Saïd Business School at the University of Oxford and Mars Catalyst, the think tank of Mars Inc., the food and beverages company, over a period of five years, the book describes how purpose promotes business growth and performance. In particular, it gives a highly accessible and readable account of how companies can determine and implement their corporate purposes, and how, by so doing, they address critical issues in their ecosystems, such as rising inequality and environmental degradation, while delivering superior performance and resilience. The book will equip executives, managers, investors, policymakers, academics, and students with tools to understand the way in which companies can build purpose-centric businesses, map and orchestrate stakeholder ecosystems, identify untapped resources, create unconventional partnerships, measure and manage performance beyond financial reporting, and adopt a new definition of profit to promote corporate purposes. The book includes fourteen case studies of companies of varying sizes, sectors, and geographies that sought to put purpose into practice. They provide deep insights into the way in which companies have delivered corporate purpose and the challenges they faced in doing this. The book stresses both the opportunity and obligation on business to reposition itself to address the changing needs of society and the planet in the twenty-first century.
Abstract
The success of growth hormone (GH) replacement in children with classical GH deficiency has led to excitement that other causes of short stature may benefit similarly. However, clinical ...experience has shown less consistent and generally less dramatic effects on adult height, perhaps not surprising in light of increased understanding of GH and growth plate biology. Nonetheless, clinical demand for GH treatment continues to grow. Upon the 20th anniversary of the US Food and Drug Administration's approval of GH treatment for idiopathic short stature, this review will consider the factors underlying the expansion of GH treatment, the biological mechanisms of GH action, the non-GH–deficient uses of GH as a height-promoting agent, biological constraints to GH action, and future directions.
Objectives
The purpose of this study was to compare procedural justice and legitimacy as correlates and predictors of compliance with the law.
Methods
A literature review produced 64 studies, 95 ...samples, and 196 effect sizes from studies published or conducted sometime between 1990 and February 2018 in which procedural justice was correlated with legitimacy and/or compliance, or legitimacy was correlated with compliance. Fifty samples included all 3 correlations, 3 samples included 2 correlations, and the remaining 42 samples included a single correlation. Two random effects meta-analyses were performed.
Results
Pooled univariate effects for all three correlations achieved significance. Although there was a high degree of heterogeneity in the results and modest evidence of publication bias in one of the subsamples, sensitivity testing indicated that no one study had an undue influence over the results. Using a generalized least squares (GLS) multivariate approach, a path analysis revealed a significant
a
path from procedural justice to legitimacy, a significant
b
path from legitimacy to compliance, and a significant
c
’ path from procedural justice to compliance, but only the
a
and
b
paths were significant when the analysis was restricted to studies with longitudinal data.
Conclusions
The current findings suggest that legitimacy beliefs are instrumental in promoting compliance with the law and that while procedural justice perceptions also appear to predict compliance, the effect was relatively weak in this meta-analysis and could not be reliably established in longitudinal datasets.
Tropical savannas have a ground cover dominated by C4 grasses, with fire and herbivory constraining woody cover below a rainfall-based potential. The savanna biome covers 50% of the African ...continent, encompassing diverse ecosystems that include densely wooded Miombo woodlands and Serengeti grasslands with scattered trees. African savannas provide water, grazing and browsing, food and fuel for tens of millions of people, and have a unique biodiversity that supports wildlife tourism. However, human impacts are causing widespread and accelerating degradation of savannas. The primary threats are land cover-change and transformation, landscape fragmentation that disrupts herbivore communities and fire regimes, climate change and rising atmospheric CO2. The interactions among these threats are poorly understood, with unknown consequences for ecosystem health and human livelihoods. We argue that the unique combinations of plant functional traits characterizing the major floristic assemblages of African savannas make them differentially susceptible and resilient to anthropogenic drivers of ecosystem change. Research must address how this functional diversity among African savannas differentially influences their vulnerability to global change and elucidate the mechanisms responsible. This knowledge will permit appropriate management strategies to be developed to maintain ecosystem integrity, biodiversity and livelihoods.
ABSTRACT
Planet formation via core accretion requires the production of kilometre-sized planetesimals from cosmic dust. This process must overcome barriers to simple collisional growth, for which the ...streaming instability (SI) is often invoked. Dust evolution is still required to create particles large enough to undergo vigorous instability. The SI has been studied primarily with single-size dust, and the role of the full evolved dust distribution is largely unexplored. We survey the polydisperse streaming instability (PSI) with physical parameters corresponding to plausible conditions in protoplanetary discs. We consider a full range of particle stopping times, generalized dust size distributions, and the effect of turbulence. We find that while the PSI grows in many cases more slowly with an interstellar power-law dust distribution than with a single size, reasonable collisional dust evolution, producing an enhancement of the largest dust sizes, produces instability behaviour similar to the monodisperse case. Considering turbulent diffusion, the trend is similar. We conclude that if fast linear growth of PSI is required for planet formation, then dust evolution producing a distribution with peak stopping times on the order of 0.1 orbits and an enhancement of the largest dust significantly above the single power-law distribution produced by a fragmentation cascade is sufficient, along with local enhancement of the dust to gas volume mass density ratio to order unity.
To evaluate the prevalence of burnout and satisfaction with work-life integration among physicians and other US workers in 2017 compared with 2011 and 2014.
Between October 12, 2017, and March 15, ...2018, we surveyed US physicians and a probability-based sample of the US working population using methods similar to our 2011 and 2014 studies. A secondary survey with intensive follow-up was conducted in a sample of nonresponders to evaluate response bias. Burnout and work-life integration were measured using standard tools.
Of 30,456 physicians who received an invitation to participate, 5197 (17.1%) completed surveys. Among the 476 physicians in the secondary survey of nonresponders, 248 (52.1%) responded. A comparison of responders in the 2 surveys revealed no significant differences in burnout scores (P=.66), suggesting that participants were representative of US physicians. When assessed using the Maslach Burnout Inventory, 43.9% (2147 of 4893) of the physicians who completed the MBI reported at least one symptom of burnout in 2017 compared with 54.4% (3680 of 6767) in 2014 (P<.001) and 45.5% (3310 of 7227) in 2011 (P=.04). Satisfaction with work-life integration was more favorable in 2017 (42.7% 2056 of 4809) than in 2014 (40.9% 2718 of 6651; P<.001) but less favorable than in 2011 (48.5% 3512 of 7244; P<.001). On multivariate analysis adjusting for age, sex, relationship status, and hours worked per week, physicians were at increased risk for burnout (odds ratio, 1.39; 95% CI, 1.26-1.54; P<.001) and were less likely to be satisfied with work-life integration (odds ratio, 0.77; 95% CI, 0.70-0.85; P<.001) than other working US adults.
Burnout and satisfaction with work-life integration among US physicians improved between 2014 and 2017, with burnout currently near 2011 levels. Physicians remain at increased risk for burnout relative to workers in other fields.
Electrochemical carbon dioxide (CO2) reduction is a promising strategy to synthesize valuable multi-carbon products (C2+) while sequestering CO2 and utilizing intermittent renewable electricity. For ...industrial deployment, CO2 electrolyzers must remain stable while selectively producing concentrated C2+ products at high rates with modest cell voltages. Here, we present a membrane electrode assembly (MEA) electrolyzer that converts CO2 to C2+ products. We perform side-by-side comparisons of state-of-the-art electrolyzer systems and find that the MEA provides the most stable cell voltage and product selectivity. We then demonstrate an approach to release concentrated gas and liquid products from the cathode outlet. This strategy achieves ∼50% and ∼80% Faradaic efficiency for ethylene and C2+ products, respectively, with cathode outlet concentrations of ∼30% ethylene and the direct production of ∼4 wt % ethanol. We characterize stability by operating continuously for 100 h, the longest stable ethylene production at current densities >100 mA cm−2 among reported CO2 electrolyzers.
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•Membrane electrode assembly design enables stable CO2 electroreduction•∼50% Faradaic efficiency for ethylene and ∼80% Faradaic efficiency for C2+ products•>30% gas outlet concentration of ethylene and direct production of ∼4 wt % ethanol•Continuous 100 h operation at >100 mA cm−2
The advent of low-cost renewable electricity and rising atmospheric CO2 has led to a focus on electrochemical CO2 reduction as a means toward low-carbon-intensity fuels and chemical feedstocks. The conversion of CO2 into C2+ hydrocarbons and oxygenates (i.e., products containing two or more carbon atoms) is attractive in light of large global market demand for these high-energy-density products. A limited number of prior studies have focused on performance in the reaction rate regime above 100 mA cm−2 generally viewed as necessary for industrial deployment. In these works, gas diffusion electrodes are used in liquid electrolyte electrochemical flow cells, which suffer in system stability and/or energy efficiency. We overcome this issue by developing a membrane electrode assembly-based electrolyzer. The combined catalyst and system strategy produces concentrated gas and liquid products and maintains performance during long-term (100 h) uninterrupted operation.
Electrochemical CO2 reduction is a promising strategy to synthesize valuable multi-carbon products (C2+) while sequestering CO2 and utilizing intermittent renewable electricity. Here, we present a stable membrane electrode assembly (MEA) electrolyzer that converts CO2 to C2+ products. This strategy achieves ∼50% and ∼80% selectivity for ethylene and C2+ products, respectively, with cathode outlet concentrations of ∼30% ethylene and the direct production of ∼4 wt % ethanol. We characterize stability by operating continuously for 100 h with steady ethylene production.
ABSTRACT Young and rapidly rotating stars are known for intense, dynamo-generated magnetic fields. Spectropolarimetric observations of those stars in precisely aged clusters are key input for ...gyrochronology and magnetochronology. We use Zeeman Doppler imaging maps of several young K-type stars of similar mass and radius but with various ages and rotational periods to perform three-dimensional (3D) numerical MHD simulations of their coronae and follow the evolution of their magnetic properties with age. Those simulations yield the coronal structure as well as the instant torque exerted by the magnetized, rotating wind on the star. As stars get older, we find that the angular momentum loss decreases with , which is the reason for the convergence on the Skumanich law. For the youngest stars of our sample, the angular momentum loss shows signs of saturation around , which is a common value used in spin evolution models for K-type stars. We compare these results to semianalytical models and existing braking laws. We observe a complex wind-speed distribution for the youngest stars with slow, intermediate, and fast wind components, which are the result of interaction with intense and nonaxisymmetric magnetic fields. Consequently, in our simulations, the stellar wind structure in the equatorial plane of young stars varies significantly from a solar configuration, delivering insight about the past of the solar system interplanetary medium.