The existence of a light dark force mediator has been tested with the KLOE detector at DAΦNE. This particle, called U, is searched for using the decay chain ϕ→ηU, η→π+π−π0, U→e+e−. No evidence is ...found in 1.5 fb−1 of data. The resulting exclusion plot covers the mass range 5<MU<470 MeV, setting an upper limit on the ratio between the U boson coupling constant and the fine structure constant, α′/α, of ⩽2×10−5 at 90% C.L. for 50<MU<420 MeV.
The CYGNO project aims to study rare events, as low-mass (few GeV) Dark Matter (DM) particle or solar neutrino interactions, exploiting the approach of the optical readout of the scintillation light ...produced in the amplification in a multiple Gas Electron Multiplier (GEM) structure, of the primary ionization originated in large volume Time Projection Chamber (TPCs).
The volume is filled with an He:CF4 gas mixture at atmospheric pressure. The 3D topology, and therefore direction of the recoils, is reconstructed thanks to the combined use of high-granularity, high sensitivity sCMOS cameras, for the precise tracking of the projection of the recoils on the GEM plane, and of fast light sensors in order to obtain the coordinate perpendicular to the camera plane.
To conclude the R&D phase, the 50 L prototype, called Long Imaging ModulE (LIME), was moved underground at the Laboratori Nazionali del Gran Sasso (LNGS) in order to study the performance of the CYGNO experimental approach in a low background environment and to assess the contributions to the background from different sources, also comparing with Monte Carlo simulations.
Stability studies and the effects of environmental condition on the light yield will be discussed, focusing on the effect of humidity on the detector response and stability amount and rate of self-sustaining micro-discharges. This is a crucial step towards the development of a large demonstrator.
•A TPC filled with a gas mixture based on light atoms as target.•The combined usage of PMTs and sCMOS camera enables the 3D tracks reconstruction.•Studies on the effects of environmental condition on the light yield.
We have measured the running of the effective QED coupling constant α(s) in the time-like region 0.6<s<0.975 GeV with the KLOE detector at DAΦNE using the Initial-State Radiation process e+e−→μ+μ−γ. ...It represents the first measurement of the running of α(s) in this energy region. Our results show a more than 5σ significance of the hadronic contribution to the running of α(s), which is the strongest direct evidence both in time- and space-like regions achieved in a single measurement. By using the e+e−→π+π− cross section measured by KLOE, the real and imaginary parts of the shift Δα(s) have been extracted. From a fit of the real part of Δα(s) and assuming the lepton universality the branching ratio BR(ω→μ+μ−)=(6.6±1.4stat±1.7syst)⋅10−5 has been determined.
In this paper we present the time resolution measurements of the Lutetium–Yttrium Oxyorthosilicate (LYSO) calorimeter prototype for the Mu2e experiment. The measurements have been performed using the ...e− beam of the Beam Test Facility (BTF) in Frascati, Italy in the energy range from 100 to 400MeV. The calorimeter prototype consisted of twenty five 30×30×130mm3, LYSO crystals read out by 10×10mm2 Hamamatsu Avalanche Photodiodes (APDs). The energy dependence of the measured time resolution can be parametrized as σt(E)=a/E/GeV⊕b, with the stochastic and constant terms a=(51±1)ps and b=(10±4)ps, respectively. This corresponds to the time resolution of (162±4)ps at 100MeV.
The INFN Cloud project was launched at the beginning of 2020, aiming to build a distributed Cloud infrastructure and provide advanced services for the INFN scientific communities. A Platform as a ...Service (PaaS) was created inside INFN Cloud that allows the experiments to develop and access resources as a Software as a Service (SaaS), and CYGNO is the betatester of this system. The aim of the CYGNO experiment is to realize a large gaseous Time Projection Chamber based on the optical readout of the photons produced in the avalanche multiplication of ionization electrons in a GEM stack. To this extent, CYGNO exploits the progress in commercial scientific Active Pixel Sensors based on Scientific CMOS for Dark Matter search and Solar Neutrino studies. CYGNO, like many other astroparticle experiments, requires a computing model to acquire, store, simulate and analyze data typically far from High Energy Physics (HEP) experiments. Indeed, astroparticle experiments are typically characterized by being less demanding of computing resources with respect to HEP ones but have to deal with unique and unrepeatable data, sometimes collected in extreme conditions, with extensive use of templates and montecarlo, and are often re-calibrated and reconstructed many times for a given data set. Moreover, the varieties and the scale of computing models and requirements are extremely large. In this scenario, the Cloud infrastructure with standardized and optimized services offered to the scientific community could be a useful solution able to match the requirements of many small/medium size experiments. In this work, we will present the CYGNO computing model based on the INFN cloud infrastructure where the experiment software, easily extendible to similar experiments to similar applications on other similar experiments, provides tools as a service to store, archive, analyze, and simulate data.
The ratio Rη=Γ(η→π+π−γ)/Γ(η→π+π−π0) has been measured by analysing 22 million ϕ→ηγ decays collected by the KLOE experiment at DAΦNE, corresponding to an integrated luminosity of 558 pb−1. The η→π+π−γ ...proceeds both via the ρ resonant contribution, and possibly a non-resonant direct term, connected to the box anomaly. Our result, Rη=0.1856±0.0005stat±0.0028syst, points out a sizable contribution of the direct term to the total width. The di-pion invariant mass for the η→π+π−γ decay could be described in a model-independent approach in terms of a single free parameter, α. The determined value of the parameter α is α=(1.32±0.08stat−0.09syst+0.10±0.02theo) GeV−2.
Aim
The neonatal intensive care unit (NICU) provides life‐saving medical care for an increasing number of newborn infants each year. NICU care, while lifesaving, does have attendant consequences ...which can include repeated activation of the stress response and reduced maternal interaction, with possible negative long‐term impacts on brain development. Here we present a neuroscientific framework for considering the impact of music on neurodevelopment in the NICU of infants born preterm and evaluate current literature on the use of music with this population to determine what is most reliably known of the physiological effects of music interventions.
Method
Using online academic databases we collected relevant, experimental studies aimed at determining effects of music listening in infants in the NICU. These articles were evaluated for methodological rigor, ranking the 10 most experimentally stringent as a representative sample.
Results
The selected literature seems to indicate that effects are present on the cardio‐pulmonary system and behavior of neonates, although the relative effect size remains unclear.
Interpretation
These findings indicate a need for more standardized longitudinal studies aimed at determining not only whether NICU music exposure has beneficial effects on the cardio‐pulmonary system, but also on the hypothalamic–pituitary–adrenal axis, brain structures, and cognitive behavioral status of these children as well.
What this paper adds
Provides a neuroscience framework for considering how music might attenuate stress in neonatal intensive care unit (NICU) infants.
Considers how repeated stress may cause negative neurodevelopmental impacts in infants born preterm.
Posits epigenetics can serve as a mechanistic pathway for music moderating the stress response.
Resumen
Los bebés prematuros, el estrés y el neurodesarrollo en la unidad de cuidados intensivos neonatales: ¿podría la música tener un impacto?
Objetivo
La unidad de cuidados intensivos neonatales (UCIN) brinda atención médica que salva vidas para un número cada vez mayor de recién nacidos cada año. El cuidado de la UCIN, aunque salva vidas, tiene consecuencias que pueden incluir la activación repetida de la respuesta al estrés y la interacción materna reducida, con posibles impactos negativos a largo plazo en el desarrollo del cerebro. Aquí presentamos un marco neurocientífico para considerar el impacto de la música en el neurodesarrollo en recién nacidos prematuros en la UCIN, y evaluamos la literatura actual sobre el uso de la música con esta población para determinar qué es lo más confiablemente conocido de los efectos fisiológicos de las intervenciones musicales.
Método
Utilizando bases de datos académicas en línea, recopilamos estudios experimentales relevantes para determinar los efectos de escuchar música en bebés en la UCIN. Estos artículos fueron evaluados por rigor metodológico, clasificando los 10 más rigurosos experimentalmente como muestra representativa.
Resultados
La literatura seleccionada parece indicar que existen efectos sobre el sistema cardiopulmonar y el comportamiento de los recién nacidos, aunque el tamaño del efecto relativo sigue sin estar claro.
Interpretación
Estos hallazgos indican la necesidad de estudios longitudinales estandarizados dirigidos a determinar no solo si la exposición musical de la NICU tiene efectos beneficiosos sobre el sistema cardiopulmonar, sino también sobre el eje hipotalámico‐pituitario‐adrenal, las estructuras cerebrales y el estado cognitivo‐conductual de estos niños también.
Resumo
Lactentes prematuores, estresse, e neurodesenvolvimento na unidade de cuidado intensivo neonatal: a música pode ter um impacto?
Objetivo
A unidade de cuidado intensivo neonatal (UCIN) oferece cuidado médico que salva vidas de um número crescente de recém‐nascidos a cada ano. O cuidado na UCIN, embora salve vidas, tem consequências que podem incluir a ativação repetida da resposta ao estresse e reduzida interação materna, com possíveis impactos negativos sobre o desenvolvimento cerebral em longo prazo. Aqui nós apresentamos uma estrutura neurocientífica para considerer o impacto da música no neurodesenvolvimento em lactentes prematuros na UCIN, e avaliamos a literatura atual no uso da música com esta população para determinar o conhecimento mais confiável sobre os efeitos fisiológicos das intervenções com música.
Método
Usando bases de dados acadêmicas online nós colecionamos estudos experimentais relevantes que visaram determinar os efeitos de ouvir música em lactentes na UCIN. Estes artigos foram avaliados quanto ao rigor metodológico, pontuando os 10 experimentalmente mais fortes como uma amostra representativa.
Resultados
A literatura selecionada parece indicar que os efeitos ocorrem no sistema cardiopulmonar e no comportamento dos lactentes, embora o relativo tamanho do efeito permaneça sem esclarecimento.
Interpretação
Estes achados indicam a necessidade de mais estudos longitudinais padronizados que visem não apenas determinar se a exposição à música na UCIN tem efeitos benéficos no sistema cardiopulmonar, mas também no eixo hipotalâmico‐pituitária‐adrenal, estruturas cerebrais, e estado cognitivo comportamental destas crianças.
What this paper adds
Provides a neuroscience framework for considering how music might attenuate stress in neonatal intensive care unit (NICU) infants.
Considers how repeated stress may cause negative neurodevelopmental impacts in infants born preterm.
Posits epigenetics can serve as a mechanistic pathway for music moderating the stress response.
This article is commented on by Haslbeck and Stegemann on page 217 of this issue.
This article's has been translated into Spanish and Portuguese.
Follow the links from the to view the translations.
PDF
