Heritage has different developmental potentials that might contribute to the sustainable development of a given area. In terms of sustainable development these potentials are not necessarily ...economic, but also include social, environmental or cultural aspects. However, heritage by itself rarely holds tangible benefits if it is not properly managed. The key challenge for attaining sustainability is to focus management on a participatory approach, which ensures public participation in the process. The paper argues that a successful and effective management of heritage depends on the people, who must be able to 1) identify the appropriate heritage, 2) link it with key stakeholders and other topics, 3) design it into a proper service, and finally 4) sell the new service to users.
This article examines garden plots in Ljubljana to present the planning of this self-sufficient vegetable production activity, which developed mostly spontaneously in all urban environments in and ...around Ljubljana. Some residents of Ljubljana, the Slovenian capital, are involved in this activity not so much because of economic necessity but because it provides recreation and relaxation, meets their need for direct contact with nature, and offers them an opportunity to produce healthy food. Typically, older people are involved in this activity, among which the number of highly educated people is unexpectedly high. The majority are happy with the plot-gardening situation. The city government has begun systematically removing garden plots in unsuitable locations, and has drafted a proposal to organize gardening areas in a way that does not pollute the environment, and at the same time provide them with suitable infrastructure. We evaluated the appropriateness of the planned locations in the draft City Municipality of Ljubljana Zoning Implementation Plan on the basis of the fulfillment of key exclusion and attraction criteria that were established based on survey answers included in support of the decision-making with the help of GIS tools. Decision-making by consensus, inclusion of public stakeholders, and establishing dialog between the city government and garden-plot users will need to be ensured in carrying out this plan.
The main goal of the entire project was so to investigate problems of daily commuting of workers, pupils and students, especially from the modal split point of view. The project is structured in two ...parts.The first part of the book is an extensive analysis of modal split by different relations (routes) and groups of commuters (pupils, secondary school pupils, students and workers). We tried to establish the areas in Slovenia where the usage of public transport is the weakest and to provide credible causes of that. The data of modal split was compared with the supply of public transport and with this we established that there is a significant link between the high public transportation usage and the high quality and competitiveness offer of public transportation vis-à-vis personal transportation.The next chapter was dedicated to particular pilot areas where the supply of public transport was greatly improved (Dol pri Ljubljani, Ankaran, Idrija, Nova Gorica). With the method of field interviewing and passenger counting we found out that the greatly improved offer of public transport does not necessarily cause a greater demand for public transport and thus the shift towards a more sustainable mobility.The synthesis of the book is in ten recommendations of possible transport policy measures for the purpose of achieving more sustainable mobility patterns with workers and students.
V prispevku je na primeru vrtičkarstva v Ljubljani predstavljen vidik načrtovanja te samooskrbne dejavnosti pridelovanja vrtnin, ki večinoma stihijsko obstaja v vseh urbanih okoljih našega kulturnega ...okolja. Z vrtičkarstvom se ukvarja nekaj odstotkov prebivalcev slovenskega glavnega mesta, ki jim ta dejavnost bolj kot ekonomsko nujo pomeni rekreacijo in sprostitev, zadovoljenje potrebe po neposrednem stiku z naravo in možnost pridelave zdrave hrane. Značilno je, da se z njo večinoma ukvarjajo starejši ljudje, med katerimi jih je več visokošolsko izobraženih, kot bi bilo pričakovati. Večina jih je z razmerami za vrtičkarstvo zadovoljna. Mestna oblast je začela načrtno odstranjevati vrtičke na zanje neprimernih lokacijah, kot nadomestilo pa je pripravila predlog vrtičkarskih območij, ki naj bi bila urejena tako, da ne bi kazila okolja, in obenem primerno infrastrukturno opremljena. Primernost načrtovanih lokacij v osnutku izvedbenega prostorskega načrta Mestne občine Ljubljana smo ovrednotili glede na izpolnjevanje pomembnih izločitvenih meril in meril privlačnosti, ki smo jih določili na podlagi anketnih rezultatov, vključenih v podporo odločanju s pomočjo orodij GIS. Pri izvedbi bo treba zagotoviti dogovorno odločanje z vključevanjem zainteresirane javnosti ter vzpostavljanje dialoga med občino in vrtičkarji.
Creativity is gaining in its importance within the knowledge society. Studying these complex dimensions and their long-term consequences for the economic and social progress was the object of ...abundant social studies n the past. But the transformation of the landscape due to creative influences, as one of the most important factors regarding structural changes in modern society, is not well represented in Slovenian geographical literature. The booklet at hand is the first attempt of establishing some geographical–developmental factors, which are encouraged by various forms of creative human activities. The geographical dispersion of human potentials is one of the key generators of creativity and social development. Some important socio–economic effects and regional disparities in the region are also in correlation with the aforementioned factors. We will try to explain some of them within a critical research view and within the form of the available space and on the other hand also show some new dimensions of social geography as a way of challenging future detailed discussions.
Glucose is the major source of brain energy and is essential for maintaining normal brain and neuronal function. Hypoglycemia
causes impaired synaptic transmission. This occurs even before ...significant reduction in global cellular ATP concentration,
and relationships among glycolysis, ATP supply, and synaptic transmission are not well understood. We demonstrate that the
glycolytic enzymes glyceraldehyde phosphate dehydrogenase (GAPDH) and 3-phosphoglycerate kinase (3-PGK) are enriched in synaptic
vesicles, forming a functional complex, and that synaptic vesicles are capable of accumulating the excitatory neurotransmitter
glutamate by harnessing ATP produced by vesicle-bound GAPDH/3-PGK at the expense of their substrates. The GAPDH inhibitor
iodoacetate suppressed GAPDH/3-PGK-dependent, but not exogenous ATP-dependent, 3 Hglutamate uptake into isolated synaptic vesicles. It also decreased vesicular 3 Hglutamate content in the nerve ending preparation synaptosome; this decrease was reflected in reduction of depolarization-induced
3 Hglutamate release. In contrast, oligomycin, a mitochondrial ATP synthase inhibitor, had minimal effect on any of these parameters.
ADP at concentrations above 0.1 m m inhibited vesicular glutamate and dissipated membrane potential. This suggests that the coupled GAPDH/3-PGK system, which
converts ADP to ATP, ensures maximal glutamate accumulation into presynaptic vesicles. Together, these observations provide
insight into the essential nature of glycolysis in sustaining normal synaptic transmission.
It had been thought that quantal size in synaptic transmission is invariable. Evidence has been emerging, however, that quantal size can be varied under certain conditions. We present evidence that ...alteration in vesicular 3Hl‐glutamate (Glu) content within the synaptosome (a pinched‐off nerve ending preparation) leads to a change in the amount of exocytotically released 3HGlu. We found that Rose Bengal, a polyhalogenated fluorescein derivative, is a quite potent membrane‐permeant inhibitor (Ki = 19 nm) of glutamate uptake into isolated synaptic vesicles. This vesicular Glu uptake inhibition was achieved largely without affecting H+‐pump ATPase. We show that various degrees of reduction elicited by Rose Bengal in 3HGlu in synaptic vesicles inside the synaptosome result in a corresponding decrease in the amount of 3HGlu released in a depolarization‐ (induced by 4‐aminopyridine) and Ca2+‐dependent manner. In contrast, fluorescein, the halogen‐free analog of Rose Bengal, which is devoid of inhibitory activity on vesicular 3HGlu uptake, failed to change the amount of exocytotically released 3HGlu. These observations suggest that glutamate synaptic transmission could be altered by pharmacological intervention of glutamate uptake into synaptic vesicles in the nerve terminal, a new mode of synaptic manipulation for glutamate transmission.
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