For the mimicry of human visual memory, a prominent challenge is how to detect and store the image information by electronic devices, which demands a multifunctional integration to sense light like ...eyes and to memorize image information like the brain by transforming optical signals to electrical signals that can be recognized by electronic devices. Although current image sensors can perceive simple images in real time, the image information fades away when the external image stimuli are removed. The deficiency between the state‐of‐the‐art image sensors and visual memory system inspires the logical integration of image sensors and memory devices to realize the sensing and memory process toward light information for the bionic design of human visual memory. Hence, a facile architecture is designed to construct artificial flexible visual memory system by employing an UV‐motivated memristor. The visual memory arrays can realize the detection and memory process of UV light distribution with a patterned image for a long‐term retention and the stored image information can be reset by a negative voltage sweep and reprogrammed to the same or an other image distribution, which proves the effective reusability. These results provide new opportunities for the mimicry of human visual memory and enable the flexible visual memory device to be applied in future wearable electronics, electronic eyes, multifunctional robotics, and auxiliary equipment for visual handicapped.
An artificial flexible visual memory system based on a UV‐motivated memristor is assembled by integrating light‐sensitive imaging sensors and resistance‐switching memristors. Sensing and memory abilities toward UV light are realized and the visual memory arrays successfully realize the detection and memory process of light distribution with a patterned image for a long‐term retention, thus providing new opportunities for the mimicry of human visual memory and enabling the flexible visual memory device to be applied in future wearable electronics, electronic eyes, multifunctional robotics, etc.
Circular RNAs (circRNAs) are a class of single-stranded, covalently closed RNA molecules with a variety of biological functions. Studies have shown that circRNAs are involved in a variety of ...biological processes and play an important role in the development of various complex diseases, so the identification of circRNA-disease associations would contribute to the diagnosis and treatment of diseases. In this review, we summarize the discovery, classifications and functions of circRNAs and introduce four important diseases associated with circRNAs. Then, we list some significant and publicly accessible databases containing comprehensive annotation resources of circRNAs and experimentally validated circRNA-disease associations. Next, we introduce some state-of-the-art computational models for predicting novel circRNA-disease associations and divide them into two categories, namely network algorithm-based and machine learning-based models. Subsequently, several evaluation methods of prediction performance of these computational models are summarized. Finally, we analyze the advantages and disadvantages of different types of computational models and provide some suggestions to promote the development of circRNA-disease association identification from the perspective of the construction of new computational models and the accumulation of circRNA-related data.
The pathogenesis of autoimmune diseases (AIDs) is not only attributed to genetic susceptibilities but also environmental factors, among which, disturbed gut microbiota has attracted increasing ...attention. Compositional and functional changes of gut microbiota have been reported in various AIDs, and increasing evidence suggests that disturbed gut microbiota contributes to their immunopathogenesis. The accepted mechanisms include abnormal microbial translocation, molecular mimicry, and dysregulation of both local and systemic immunity. Studies have also suggested microbiota-based classification models and therapeutic interventions for patients with AIDs. Further in-depth mechanistic studies on microbiota–autoimmunity interplay in AIDs are urgently needed and underway to explore novel and precise diagnostic biomarkers and develop disease and patient-tailored therapeutic strategies.
The compositional and functional changes of gut microbiota have been implicated in various autoimmune diseases (AIDs) by high-throughput techniques such as metagenomic sequencing.Correlation studies in humans and interventional studies in animal models have suggested that disturbed gut microbiota is involved in the immunopathogenesis of AIDs.The mechanisms of disturbed gut microbiota include abnormal microbial translocation, molecular mimicry, and dysregulation of both local and systemic immunity.In-depth deciphering of gut microbiota will help us to develop new microbiota-based assessments and interventions for patients with AIDs, which can help with their diagnosis, prognosis and treatment.
Circular RNAs （circRNAs） are recently identified as a naturally occurring family of widespread and diverse endogenous noncoding RNAs that may regulate gene expression in mammals . They are unusually ...sta- ble RNA molecules with cell type- or developmental stage-specific expression patterns . Exosomes are small membrane vesicles of endocytic origin secreted by most cell types. They contain a specific cargo of protein, mRNA and microRNA species, which can modulate recipient cell behaviors and may be used as biomarkers for diagnosis of human diseases .
The removal of C2H2 and C2H6 from C2H4 streams is of great significance for feedstock purification to produce polyethylene and other commodity chemicals but the simultaneous adsorption of C2H6 and ...C2H2 over C2H4 from a ternary mixture has never been realized. Herein, a robust metal–organic framework, TJT‐100, was designed and synthesized, which demonstrates remarkably selective adsorption of C2H2 and C2H6 over C2H4. Breakthrough experiments show that TJT‐100 can be used as an adsorbent for high‐performance purification of C2H4 from a ternary mixture of C2H2/C2H4/C2H6 (0.5:99:0.5) to afford a C2H4 purity greater than 99.997 %, beyond that required for ethylene polymerization. Computational studies reveal that the uncoordinated carboxylate oxygen atoms and coordinated water molecules pointing towards the pore can trap C2H2 and C2H6 through the formation of multiple C−H⋅⋅⋅O electrostatic interactions, while the corresponding C2H4–framework interaction is unfavorable.
A robust porous metal–organic framework was synthesized and utilized for the highly selective separation of C2H4 from a ternary mixture of C2 hydrocarbons. After a single operation, the C2H4 purity of the outlet was greater than 99.997 %.
A new polyhedron-based metal-organic framework (MOF), namely {Co6(OH)2(H2O)4 (cpt)9(NO3)(DMF)13} (1, Hcpt = 4-(4′-carboxyphenyl)-1,2,4-triazole), was constructed by employment of a bifunctional ...triazolyl-carboxyl ligand Hcpt. Single crystal X-ray structural analysis shows that compound 1 features a rare hexanuclear {Co6(OH)2(H2O)6}10+ cluster and could be topologically viewed as a 10-connected bct net. Furthermore, compound 1 comprises octahedral cages with the inner diameter of 19.6✕12.9 Å2 and 2D pore systems along the a and b axis with high density of open metal centers generated by the removal of coordinated water molecules, which contribute to a high CO2 adsorption capacity and significantly selective capture for CO2 over CH4 around room temperature. In addition, the resulting activated 1a could behave as the heterogeneous Lewis catalyst facilitates the chemical fixation of CO2 coupling with epoxides into cyclic carbonates under mind conditions.
A new polyhedron-based MOF was constructed by employment of a bifunctional triazolyl-carboxyl ligand Hcpt. This compound features a rare hexanuclear {Co6(OH)2(H2O)6}10+ cluster and could be topologically viewed as a 10-connected bct net. The octahedral cages and 2D pore systems with high density of open metal centers contribute to a high CO2 adsorption capacity and significantly selective capture for CO2 over CH4 around room temperature. In addition, the resulting activated compound could behave as the heterogeneous Lewis catalyst facilitates the chemical fixation of CO2 coupling with epoxides into cyclic carbonates under mind conditions. Display omitted
•A new polyhedron-based MOF has been constructed.•The compound is composed of a rare hexanuclear {Co6(OH)2(H2O)6}10+ cluster and has a 10-connected bct net.•The compound has the capability of selective sorption and chemical conversion for CO2.•The possible catalytic mechanism was discussed in detail.
•Macroalgae residue is promising raw material for producing biochar.•Biochar derived from pigments-extracted macroalgae is a promising adsorbent.•The malachite green adsorption capacity of MDBC800 is ...5306.2 mg/g.
Biochar is known to efficiently adsorb dyes from wastewater. In this study, biochar was derived from macroalgae residue by pyrolysis, and the influence of varying temperature (from 400 °C to 800 °C) on biochar characteristics was investigated. Among the biochar samples tested, macroalgae-derived biochar possessing highly porous structure, special surface chemical behavior and high thermal stability was found to be efficient in removing malachite green, crystal violet and Congo red. The biochar derived by pyrolysis at 800 °C showed the highest adsorption capacity for malachite green (5306.2 mg g−1). In this study, the transformation of microalgae residue into a highly efficient dye adsorbent is a promising procedure for economic and environmental protection.
With the rapid expanse and progress of flexible/wearable electronics, it is highly desirable to develop flexible/stretchable power sources, as it is a key technique for the realization of fully ...flexible integrated systems. Lithium‐ion batteries (LIBs) are one of the most ideal candidates of power sources because of their attractive features of high energy density, high power density, and long cycle life. The recent progress of flexible/stretchable LIBs from the viewpoint of device structure design is reviewed herein, as the device configurations are vital for the practical applications of flexible/stretchable LIBs. The remaining challenges and future opportunities for this emerging field are also highlighted from the viewpoint of practical applications.
Device configurations are vital for the practical applications of flexible/stretchable lithium‐ion batteries, which affect the electrochemical performance, mechanical flexibility or stretchability, and practical applications. This review summarizes recent progress in the development of flexible/stretchable LIBs in terms of device configurations, and their applications in fully flexible/stretchable integrated systems.
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•AOPs are effective technologies for oxidative pathogen elimination.•The key mechanisms of AOPs-based disinfection are discussed.•The characteristics of ROS and their inactivation ...pathways are showcased.•ROS oxidatively damaged the cell membrane, enzymes, and genetic materials.•Operational cost and energy consumption of different AOPs are analyzed.
The disinfection of microbial pathogens plays an important role in control of waterborne diseases and health issues. Recently, advanced oxidation processes (AOPs) are applied as powerful and effective technologies for wastewater purification and pathogen elimination. This review will showcase the recent endeavors in the fields and provide a comprehensive understanding of pathogens inactivation by diverse AOPs (i.e., Fenton processes, photocatalysis, electrochemical advanced oxidation processes (EAOPs), sonolysis, ozonation, and persulfate-based AOPs). The mechanisms of AOPs-based disinfection include the destruction of cell envelope, enzymes, and intracellular substances via diverse reactive oxygen species (ROS). The primary ROS are HO·, SO4•−, O2•−, 1O2, and O3, which exhibit different oxidative capacities, and can react with cell envelope to destroy the permeability of cell membrane. Specifically, this review emphasizes on the performances and mechanisms of different AOPs systems in microbial inactivation as well as perspectives in practical applications of disinfection in terms of feasibility, operating cost, and sustainability.
Flexible energy‐storage devices are attracting increasing attention as they show unique promising advantages, such as flexibility, shape diversity, light weight, and so on; these properties enable ...applications in portable, flexible, and even wearable electronic devices, including soft electronic products, roll‐up displays, and wearable devices. Consequently, considerable effort has been made in recent years to fulfill the requirements of future flexible energy‐storage devices, and much progress has been witnessed. This review describes the most recent advances in flexible energy‐storage devices, including flexible lithium‐ion batteries and flexible supercapacitors. The latest successful examples in flexible lithium‐ion batteries and their technological innovations and challenges are reviewed first. This is followed by a detailed overview of the recent progress in flexible supercapacitors based on carbon materials and a number of composites and flexible micro‐supercapacitors. Some of the latest achievements regarding interesting integrated energy‐storage systems are also reviewed. Further research direction is also proposed to surpass existing technological bottle‐necks and realize idealized flexible energy‐storage devices.
Flexible energy‐storage devices are indispensable to the development of flexible electronics. This review surveys recent achievements, focusing on flexible lithium‐ion batteries and flexible supercapacitors combined with integrated energy‐storage systems.
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