Cardiac masses are rare entities that can be challenging in clinical diagnosis and management. Cardiac masses can be detected incidentally in patients with an asymptomatic course or may cause ...systemic inflammation findings due to inflammatory cytokine release or symptoms such as shortness of breath, chest pain, syncope, sudden cardiac death, and mortality due to the location of the mass. Cardiac masses associated with systemic inflammatory disorders are uncommon in this disease group. This case report will present a case with an asymptomatic IgG4-related left atrial mass detected in routine echocardiographic control imaging due to rheumatic valve disease.
In this work, we explore the dynamics of entanglement of an isolated quantum system consisting of two time-dependent, coupled harmonic oscillators. Through the use of a numerical method that relies ...on the estimation of the system's Wigner representation by a specific Gaussian function, we investigate the time evolution of the entanglement entropy after an instant quench in the inherent parameters of the system. Besides, from the comparison of the results obtained from the analytical expression for the time-dependent von Neumann entropy with the numerically computed entropy data, the effectiveness of the numerical method is tested for a variety of angular frequency combinations. Also, we analyze how the entropy of entanglement change as a function of time.
In this study, it was aimed to determine of P. multocida, M. haemolytica, H. somni and M. bovis in macroscopically healthy cattle lungs by PCR. The study was carried out on 82 macroscopically healthy ...cattle lung. DNA extraction was performed to the lung samples. PCR was then performed using all specific primers. By molecular evaluation, positive results were achieved for P. multocida, M. haemolytica, H. somni and M. bovis in 4 (4.8 %), 4 (4.8 %), 6 (7.3 %) and 3 (3.6 %) of the samples, respectively. Mix infections were detected in five samples. Of the samples, two were positive for both P. multocida and M. haemolytica, two were positive for both M. haemolytica and H. somni and one was positive for both P. multocida and H. somni. However, a positive sample, which carried all of pathogens, was not detected. In conclusion, P. multocida, M. haemolytica, H. somni and M. bovis are the important opportunistic pathogens of respiratory tract in cattle and these pathogens have a major role during infections. But multifactorial nature of bovine respiratory disease and immune system affected the formation of the disease. Hence, firstly cattle’s immunity should be strengthened and other conditions should be kept under control.
En este estudio se tuvo como objetivo determinar P. multocida, M. haemolytica, H. somni y M. bovis en pulmones de bovinos macroscópicamente sanos mediante PCR. El estudio se llevó a cabo en 82 ...pulmones de bovinos macroscópicamente sanos. Se realizó la extracción de ADN de las muestras pulmonares. Después, se realizó la PCR utilizando todos los cebadores específicos. Mediante evaluación molecular, se lograron resultados positivos para P. multocida, M. haemolytica, H. somni y M. bovis en 4 (4.8 %), 4 (4.8 %), 6 (7.3 %) y 3 (3.6 %) de las muestras, respectivamente. Se detectaron infecciones mixtas en cinco muestras. De las muestras, dos fueron positivas tanto para P. multocida como para M. haemolytica, dos fueron positivas tanto para M. haemolytica como para H. somni y una fue positiva tanto para P. multocida como para H. somni. Sin embargo, no se detectó una muestra positiva que transportara todos los patógenos. En conclusión, P. multocida, M. haemolytica, H. somni y M. bovis son los patógenos oportunistas importantes del tracto respiratorio en bovinos y estos patógenos tienen un papel importante durante las infecciones. Pero la naturaleza multifactorial de la enfermedad respiratoria bovina y el sistema inmunológico afectaron la formación de la enfermedad. Por lo tanto, en primer lugar, se debe fortalecer la inmunidad de los bovinos y se deben mantener bajo control otras condiciones.
BackgroundFournier gangrene (FG) is a necrotizing fasciitis involving perianal and abdominal regions. It progresses quickly and requires urgent intervention. With the use of vacuum-assisted closure ...(VAC) treatment applied during clinical follow-up and the use of superomedial thigh flap in the region, the treatment is completed with an effective, functional, and rapid approach. This study examines the clinical details of this method for reconstruction. MethodsThe study included 15 patients who underwent superomedial thigh flap in VAC treatment reconstruction for tissue defect after FG debridement from 2016 to 2020. The patients were examined in the form of clinical evaluation with hospital admission and surgical evaluation in the postop process. ResultsIn patients with wound maturation and sufficient granulation, superomedial thigh flap application followed by VAC treatment soon after shortened the operation time, shortened the postop drain time, and provided effective treatment of dead space. An aesthetic and functional result was obtained with the proximity of the flap to the area. In addition, due to the sensory branches present in the flap, a sensory result was obtained according to the ratio of flap size. ConclusionsSuperomedial thigh flap provides a practical, effective, and fast solution to the tissue defect that occurs after FG debridement. Effective results can be obtained when combined with VAC therapy.
Background: Pruritus is a common symptom of many dermatological and
systemic diseases. It is a common complaint among patients with
psoriasis of the chronic plaque type. Patients with pruritus suffer
...from more severe psoriasis although some authors did not find a
significant relationship between pruritus intensity and psoriasis
severity. Aims: In this study, we aimed to investigate the
relationship between clinical features and symptoms among psoriasis
patients. And also we aimed to evaluate whether the severity of
disease, depression and quality of life scores could effect these
symptoms or not. Methods: Eighty seven patients with psoriasis were
enrolled in this study. Epidemiological data of patients were noted.
Clinical symptoms, such as pruritus, pain, burning, exudation,
bleeding, weakness, etc. were interrogated. The answers to these
questions were classified as ′never′, ′rare′,
′sometimes′, ′often′ and ′all the
time′. Psoriasis Area and Severity Index (PASI), Dermatology Life
Quality Index (DLQI), Hamilton Anxiety-Depression Scale (HAD) were
calculated for each patient. PASI and DLQI scores were classified as
≥ and < 10. Results: We found that the most frequent symptom
was pruritus (96.6%). Other frequent symptoms were burning (56.3%),
exudation (56.3%) and bleeding (49.4%). Hurting, sensitiveness and
bothering were more frequent in women. Percentages of hurting, pain,
exudation and weakness symptoms had been increasing with age. Frequency
of weakness was significantly high in PASI ≥ 10 patients.
Conclusion: Pruritus is a very common symptom in psoriasis. Burning,
exudation and bleeding are also common symptoms seen in psoriasis. New
scoring systems including symptoms of psoriasis patients may be
developed for evaluating the severity of the disease.
Unmet needs of rheumatoid arthritis (RA) patients regarding physician/patient communication, treatment preferences and quality of life issues were investigated in a Turkish survey study.
The study ...was conducted with the contribution of 33 rheumatologists, and included 519 RA patients. The study population included patients who had been on biologic therapy for >6 months and were still receiving biologic therapy (BT group), and those who were biologic naive, but found eligible for biologic treatment (NBT group). Of the RA patients, 35.5% initially had a visit to an internal disease specialist, 25.5% to a physical therapy and rehabilitation specialist, and 12.2% to a rheumatology specialist for their RA complaints. The diagnosis of RA was made by a rheumatologist in 48.2% of patients.
The majority of RA patients (86.3%) visit their doctor within 15-week intervals. Most of the physician-patient communication focused on disease symptoms (99.0%) and impact of the disease on quality of life (61.8%). The proportion of RA patients who perceived their health status as good/very good/excellent was higher in the BT group than in the NBT group (74.3% vs. 51.5%, p<0.001). However, of those RA patients in the NBT group, only 24.8% have been recommended to start a biologic treatment by their doctors. With respect to dose frequency options, once-monthly injections were preferred (80%) to a bi-weekly injection schedule (8%).
In conclusion, RA patients receiving biologic therapy reported higher rates of improved symptoms and better quality of life and seemed to be more satisfied with their treatment in our study.
Object: To prepare a national guideline for Otorhinolaryngologist who treat allergic rhinitis patients Methods: The study was conducted by three authors, namely the writing support team. The support ...team made the study plan, determined the writing instructions, chose the subgroups including the advisory committee, the advisors for authors and the authors. A workshop was organized at the very beginning to explain the details of the study to the team. Advisors took the chance to meet their coworkers in their subgroups and determined the main headings and subheadings of the guideline, together with the authors. After key words were determined by the authors, literature search was done in various databases. The authors keep in touch with the advisors and the advisors with the advisory committee and the support group at every stage of the study. National and International published articles as well as the abstracts of unpublished studies, imperatively presented in National Congresses, were included in this guideline. Only Guideline and meta-analyses published in last seven years (2013-2017) and randomized controlled studies published in last two years (2015-2017) were included. After all work was completed by the subgroups, support team brought all work together and edited the article. Results: A detailed guideline about all aspects of allergic rhinitis was created. Conclusion: The authors believe that this guideline will enable a compact and up-to-date information on allergic rhinitis to healthcare professionals. This guideline is the first in the field of Otolaryngology in Turkey. It should be updated at regular intervals. Key words: Allergic rhinitis, guideline, rhinitis
Aim ― The present study aimed to detect mecA and staphylococcal cassette chromosome mec (SCCmec) types in methicillin-resistant Staphylococcus aureus (MRSA) isolates obtained from various clinical ...samples in two university hospitals. It was also aimed to make comparison amongst the isolates. Materials and Methods ― A total of 99 MRSA strains isolated from various clinical samples between 2011-2015 were included in the study. Bacterial deoxyribonucleic acid (DNA) was extracted from Staphylococcus aureus strains using GF-1 DNA extraction Kit (Vivantis, Malaysia). mecA gene were detected, and SCCmec cassette types were determined by multiplex polymerase chain reaction (PCR) first, and following specific PCR. Specific MRSA strains such as COL type I, PER3 type Ia, and HU25 type IIIa were used as the quality control strains for optimization of multiplex PCR. The amplification products were electrophoresed using agarose gel electrophoresis in TAE buffer (mixture of tris base, acetic acid and ethylenediaminetetraacetic acid). Results ― mecA gene was detected in 60 Staphylococcus aureus isolates, and these were identificated as MRSA. Amongst the MRSA strains, SCCmec type III was the most frequent cassette type (42 isolates, 70.0%). SCCmec type I was detected in 27 isolates (45.0%), type II was in 26 isolates (43.3%), and type V in 23 isolates (38.3%). Conclusion ― In the present study, the most frequent cassette was detected as SCCmec type III in concordance with the studies conducted in Turkey and in some regions in the world. In conclusion, determination of epidemiological and molecular characteristics of MRSA strains has critical importance because of the difficulties in the treatment and of the nosocomial infections and epidemics they caused. The data obtained would contribute to the preventions in terms of epidemiology.
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