The
13C NMR spectra of para-substituted α-phenylcinnamic and 3- and 4-pyridylacrylic acids, with a wide range of substituents effects, were determined in deuterated dimethylsulfoxide (DMSO-
d
6). The ...effect of substituents in both the α-phenyl and β-pyridine groups in these acids is investigated using linear free energy relationships and multiple regression analysis as applied to
13C NMR chemical shifts of the C
α and C
β of the ethylenic bond and the carboxylic group carbon. Dissection of the α-phenyl substituent effects into the inductive and resonance components, using the dual substituent parameter (DSP) method, points to a blend of inductive and resonance effects in the π-electronic system.
Apoptosis or programmed cell death is a genetically controlled process that eliminates harmful or unwanted cells. This process plays an important role during development by contributing to tissue ...sculpting and in maintaining homeostasis of cell number in a variety of tissues. Recently, we have identified a family of apoptotic inhibitory proteins, naip, hiap1 & hiap2, and xiap, which are capable of suppressing caspases, key proteolytic mediators of apoptosis. To elucidate a potential role for xiap during development, we have analyzed the expression patterns of the murine equivalent, miap3, at various stages of mouse development. In situ hybridization studies have revealed a ubiquitous expression pattern for miap3 mRNA in a variety of developing organs, including brain, heart, lung, liver, pancreas, intestines and skin. Similar results were observed with wholemount in situ hybridization. In addition, immunohistochemical analysis demonstrated that miap3 is widely expressed during embryonic days 9.5 to 16.5. Furthermore, miap3 protein expression was observed in many of the adult mouse tissues and in day 9 to 13 mouse embryos by western blot analysis. These results demonstrate that miap3 is ubiquitously distributed suggesting that it is an essential regulator of cell survival during murine development.
There is an increasing number of health products which fall under the definition of "nanomaterials" currently available in the marketplace in Canada. However, the safety assessment and risk ...management of these products pose challenges as the knowledge in the field is evolving. The objective of this paper is to highlight the present state of regulatory oversight for nanomaterial-based health products in Canada. To meet its statutory obligations to protect and promote the safety of Canadians, Health Canada continues to rely on the authorities of existing legislative frame work, which require the assessment of potential risks and benefits of products before they are authorized for sale. Health Canada has developed a Policy Statement on the Working Definition of Nanomaterial, which is now available on its website.
The capital value evaluation on the farms Tica, N.(Poljoprivredni fakultet, Novi Sad (Serbia)); Pejanovic, R.(Poljoprivredni fakultet, Novi Sad (Serbia)); Cvetkovic, N.(Institut ekonomskih nauka, Beograd (Serbia)) ...
Agroekonomika (Serbia),
(2002)
31
Journal Article
The aim of this paper is to point out the importance of the capital value evaluation on the farms having in mind the characteristics of domestic conditions and environment. The core idea is to ...develop the concept which is suppose to contribute to the more efficient functioning and developing of the privatization process in the agriculture sector in the time of late transition.
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