Abstract
The highest-energy known gamma-ray sources are all located within 0.°5 of extremely powerful pulsars. This raises the question of whether ultra-high-energy (UHE; >56 TeV) gamma-ray emission ...is a universal feature expected near pulsars with a high spin-down power. Using four years of data from the High Altitude Water Cherenkov Gamma-Ray Observatory, we present a joint-likelihood analysis of 10 extremely powerful pulsars to search for subthreshold UHE gamma-ray emission correlated with these locations. We report a significant detection (>3
σ
), indicating that UHE gamma-ray emission is a generic feature of powerful pulsars. We discuss the emission mechanisms of the gamma rays and the implications of this result. The individual environment, such as the magnetic field and particle density in the surrounding area, appears to play a role in the amount of emission.
Intracerebral hemorrhage (ICH) and perihematomal edema (PHE) volumes are major determinants of ICH outcomes as is the immune system which plays a significant role in damage and repair. Thus, we ...performed whole-transcriptome analyses of 18 ICH patients to delineate peripheral blood genes and networks associated with ICH volume, absolute perihematomal edema (aPHE) volume, and relative PHE (aPHE/ICH; rPHE). We found 440, 266, and 391 genes correlated with ICH and aPHE volumes and rPHE, respectively (
p
< 0.005, partial-correlation > |0.6|). These mainly represented inflammatory pathways including NF-κB, TREM1, and Neuroinflammation Signaling—most activated with larger volumes. Weighted Gene Co-Expression Network Analysis identified seven modules significantly correlated with these measures (
p
< 0.05). Most modules were enriched in neutrophil, monocyte, erythroblast, and/or T cell-specific genes. Autophagy, apoptosis, HIF-1α, inflammatory and neuroinflammatory response (including Toll-like receptors), cell adhesion (including MMP9), platelet activation, T cell receptor signaling, and mRNA splicing were represented in these modules (FDR
p
< 0.05). Module hub genes, potential master regulators, were enriched in neutrophil-specific genes in three modules. Hub genes included NCF2, NCF4, STX3, and CSF3R, and involved immune response, autophagy, and neutrophil chemotaxis. One module that correlated negatively with ICH volume correlated positively with rPHE. Its genes and hubs were enriched in T cell-specific genes including hubs LCK and ITK, Src family tyrosine kinases whose modulation improved outcomes and reduced BBB dysfunction following experimental ICH. This study uncovers molecular underpinnings associated with ICH and PHE volumes and pathophysiology in human ICH, where knowledge is scarce. The identified pathways and hub genes may represent novel therapeutic targets.
We report the first detection of a TeV 7-ray flux from the solar disk (6.3a), based on 6.1 years of data from the High Altitude Water Cherenkov (HAWC) observatory. The 0.5-2.6 TeV spectrum is well ...fit by a power law, dN/dE=A(E/1 TeV)-7, with A = (1.6 & PLUSMN; 0.3) x 10-12 TeV-1 cm-2 s-1 and 7 = 3.62 & PLUSMN; 0.14. The flux shows a strong indication of anticorrelation with solar activity. These results extend the bright, hard GeV emission from the disk observed with Fermi-LAT, seemingly due to hadronic Galactic cosmic rays showering on nuclei in the solar atmosphere. However, current theoretical models are unable to explain the details of how solar magnetic fields shape these interactions. HAWC's TeV detection thus deepens the mysteries of the solar-disk emission.
Abstract
The MGRO J2019+37 region is one of the brightest sources in the sky at TeV energies. It was detected in the second HAWC catalog as 2HWC J2019+367 and here we present a detailed study of this ...region using data from HAWC. This analysis resolves the region into two sources: HAWC J2019+368 and HAWC J2016+371. We associate HAWC J2016+371 with the evolved supernova remnant CTB 87, although its low significance in this analysis prevents a detailed study at this time. An investigation of the morphology (including possible energy-dependent morphology) and spectrum for HAWC J2019+368 is the focus of this work. We associate HAWC J2019+368 with PSR J2021+3651 and its X-ray pulsar wind nebula, the Dragonfly nebula. Modeling the spectrum measured by HAWC and Suzaku reveals a ∼7 kyr pulsar and nebula system producing the observed emission at X-ray and
γ
-ray energies.
The discovery of the TeV point source 2HWC J2006+341 was reported in the second HAWC gamma-ray catalog. We present a follow-up study of this source here. The TeV emission is best described by an ...extended source with a soft spectrum. At GeV energies, an extended source is significantly detected in Fermi-LAT data. The matching locations, sizes, and spectra suggest that both gamma-ray detections correspond to the same source. Different scenarios for the origin of the emission are considered and we rule out an association to the pulsar PSR J2004+3429 due to extreme energetics required, if located at a distance of 10.8 kpc.
The High Altitude Water Cherenkov (HAWC) Gamma-Ray Observatory continuously detects TeV photons and particles within its large field of view, accumulating every day a deeper exposure of two-thirds of ...the sky. We analyzed 1523 days of HAWC live data acquired over four and a half years, in a follow-up analysis of 138 nearby (z < 0.3) active galactic nuclei from the Third Catalog of Hard Fermi-LAT sources culminating within 40° of the zenith at Sierra Negra, the HAWC site. This search for persistent TeV emission used a maximum-likelihood analysis assuming intrinsic power-law spectra attenuated by pair production of gamma-ray photons with the extragalactic background light. HAWC clearly detects persistent emission from Mkn 421 and Mkn 501, the two brightest blazars in the TeV sky, at 65 and 17 level, respectively. Marginal evidence, just above the 3 level, was found for three other known very high-energy emitters: the radio galaxy M87 and the BL Lac objects VER J0521+211 and 1ES 1215+303, the latter two at z ∼ 0.1. We find a 4.2 evidence for collective emission from the set of 30 previously reported very high-energy sources, with Mkn 421 and Mkn 501 excluded. Upper limits are presented for the sample under the power-law assumption and in the predefined (0.5-2.0), (2.0-8.0), and (8.0-32.0) TeV energy intervals.
Abstract
Galactic gamma-ray diffuse emission (GDE) is emitted by cosmic rays (CRs), ultra-relativistic protons, and electrons, interacting with gas and electromagnetic radiation fields in the ...interstellar medium. Here we present the analysis of teraelectronvolt diffuse emission from a region of the Galactic plane over the range in longitude of
l
∈ 43°, 73°, using data collected with the High Altitude Water Cherenkov (HAWC) detector. Spectral, longitudinal, and latitudinal distributions of the teraelectronvolt diffuse emission are shown. The radiation spectrum is compatible with the spectrum of the emission arising from a CR population with an
index
similar to that of the observed CRs. When comparing with the
DRAGON
base model
, the HAWC GDE flux is higher by about a factor of 2. Unresolved sources such as pulsar wind nebulae and teraelectronvolt halos could explain the excess emission. Finally, deviations of the Galactic CR flux from the locally measured CR flux may additionally explain the difference between the predicted and measured diffuse fluxes.
Abstract
This paper reports on the
γ
-ray properties of the 2018 Galactic nova V392 Per, spanning photon energies ∼0.1 GeV–100 TeV by combining observations from the Fermi Gamma-ray Space Telescope ...and the HAWC Observatory. As one of the most rapidly evolving
γ
-ray signals yet observed for a nova, GeV
γ
-rays with a power-law spectrum with an index Γ = 2.0 ± 0.1 were detected over 8 days following V392 Per’s optical maximum. HAWC observations constrain the TeV
γ
-ray signal during this time and also before and after. We observe no statistically significant evidence of TeV
γ
-ray emission from V392 Per, but present flux limits. Tests disfavor the extension of the Fermi Large Area Telescope spectrum to energies above 5 TeV by 2 standard deviations (95%) or more. We fit V392 Per’s GeV
γ
-rays with hadronic acceleration models, incorporating optical observations, and compare the calculations with HAWC limits.
Abstract
The High Altitude Water Cherenkov (HAWC) Gamma-Ray Observatory surveys the very high-energy sky in the 300 GeV to >100 TeV energy range. HAWC has detected two blazars above 11
σ
, Markarian ...421 (Mrk 421) and Markarian 501 (Mrk 501). The observations are comprised of data taken in the period between 2015 June and 2018 July, resulting in ∼1038 days of exposure. In this work, we report the time-averaged spectral analyses for both sources, above 0.5 TeV. Taking into account the flux attenuation due to the extragalactic background light, the intrinsic spectrum of Mrk 421 is described by a power law with an exponential energy cutoff with index
α
=
2.26
±
0.12
stat
−
0.2
+
0.17
sys
and energy cutoff
E
c
=
5.1
±
1.6
stat
−
2.5
+
1.4
sys
TeV, while the intrinsic spectrum of Mrk 501 is better described by a simple power law with index
α
=
2.61
±
0.11
stat
−
0.07
+
0.01
sys
. The maximum energies at which the Mrk 421 and Mrk 501 signals are detected are 9 and 12 TeV, respectively. This makes these some of the highest energy detections to date for spectra averaged over years-long timescales. Since the observation of gamma radiation from blazars provides information about the physical processes that take place in their relativistic jets, it is important to study the broadband spectral energy distributions (SEDs) of these objects. For this purpose, contemporaneous data in the gamma-ray band to the X-ray range, and literature data in the radio to UV range, were used to build time-averaged SEDs that were modeled within a synchrotron-self Compton leptonic scenario.
Abstract
We report TeV gamma-ray observations of the ultra-high-energy source MGRO J1908+06 using data from the High Altitude Water Cherenkov Observatory. This source is one of the highest-energy ...known gamma-ray sources, with emission extending past 200 TeV. Modeling suggests that the bulk of the TeV gamma-ray emission is leptonic in nature, driven by the energetic radio-faint pulsar PSR J1907+0602. Depending on what assumptions are included in the model, a hadronic component may also be allowed. Using the results of the modeling, we discuss implications for detection prospects by multi-messenger campaigns.
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