We present a direct measurement of the width of the W boson using the shape of the transverse mass distribution of W --> enu candidate events. Data from approximately 1 fb(-1) of integrated ...luminosity recorded at square root of s = 1.96 TeV by the D0 detector at the Fermilab Tevatron pp collider are analyzed. We use the same methods and data sample that were used for our recently published W boson mass measurement, except for the modeling of the recoil, which is done with a new method based on a recoil library. Our result, 2.028 +/- 0.072 GeV, is in agreement with the predictions of the standard model.
We present measurements of direct photon pair production cross sections using 8.5fb-1 of data collected with the D0 detector at the Fermilab Tevatron $p\bar{p}$ collider. The results are presented as ...differential distributions of the photon pair invariant mass $dσ/dM_{γγ}$, pair transverse momentum $dσ/dp^{γγ}_{T}$, azimuthal angle between the photons $dσ/dΔφ_{γγ}$, and polar scattering angle in the Collins–Soper frame $dσ/d|cos θ*|$. Measurements are performed for isolated photons with transverse momenta $p^γ_T$ > 18(17)GeV for the leading (next-to-leading) photon in $p_T$, pseudorapidities , |$η^γ$| < 0.9 and a separation in η–φ space Δ$\mathscr{R}_{γγ}$ >0.4. We present comparisons with the predictions from Monte Carlo event generators DIPHOX and RESBOS implementing QCD calculations at next-to-leading order, 2γNNLO at next-to-next-to-leading order, and SHERPA using matrix elements with higher-order real emissions matched to parton shower.
Objective:This study tests the hypotheses that enoxaparin, a low molecular weight heparin and potent inhibitor of factor Xa, alone or in combination with standard heparin, inhibits thrombin formation ...and activity and modulates complement activation and neutrophil elastase release during cardiopulmonary bypass in baboons.
Methods: After preliminary studies to determine doses and possible species differences to anticoagulants and protamine, 27 anesthesized baboons had normothermic cardiopulmonary bypass with standard, unfractionated, porcine intestinal heparin, enoxaparin, or a combination of heparin and enoxaparin. Protamine in appropriate doses was used to reverse anticoagulation. Blood samples were obtained at 6 time points. Activated clotting times were monitored; template bleeding times were measured before and up to 24 hours after cardiopulmonary bypass.
Results: Hemodynamic measurements were not affected by the anticoagulant. Activated clotting times remained above 400 seconds throughout bypass, and no clots were observed. The anticoagulant did not alter platelet count, aggregation to adenosine diphosphate, release of β-thromboglobulin, release of neutrophil elastase, or complement C3b/c and C4b/c. Enoxaparin alone, but not in combination, significantly reduced plasma levels of prothrombin fragment F1.2, fibrinopeptide A, and thrombin-antithrombin complexes but prolonged template bleeding times for more than 24 hours.
Conclusion: Enoxaparin significantly reduces thrombin formation and activity during cardiopulmonary bypass but does not suppress complement activation and neutrophil elastase release and is not adequately reversed by protamine after bypass. (J Thorac Cardiovasc Surg 1998;116:1043-51)
Cardiopulmonary bypass causes hemorrhagic complications, and initiates a chemical and cellular inflammatory response. Contact of blood with synthetic surfaces leads to qualitative and quantitative ...alterations in platelets, neutrophils, complement, and contact systems. Despite the fact that cardiopulmonary bypass is carried out in the presence of high doses of heparin, there is significant activation of both platelets and neutrophils. Thrombin is protected on cell and fibrin surfaces from antithrombin, even in the presence of high doses of heparin (approximately 5 U/ml). We therefore studied the effect of a small (Mr = 497), highly effective (Ki = 41 pM), reversible tripeptide inhibitor of thrombin, DUP 714 (1 microM), in a well characterized model of simulated extracorporeal circulation. In the absence of DUP 714, platelet counts decreased by 75% 5 min after the start of extracorporeal bypass and increased to 48% at 120 min of recirculation. DUP 714 significantly preserved platelet counts, decreased plasma levels of platelet beta-thromboglobulin levels, but did not prevent a decrease in sensitivity of platelets to adenosine diphosphate. Kallikrein-C1-inhibitor and C1-C1-inhibitor complexes increased progressively from 0.32 U/ml to 0.67 U/ml and from 4.45 U/ml to 7.25 U/ml, respectively, during 120 min of recirculation without DUP 714. Addition of DUP 714 significantly inhibited kallikrein-C1-inhibitor complex formation but did not affect C1-C1-inhibitor complexes. In the absence of DUP 714, human neutrophil elastase levels rose from a baseline of 0.01 +/- 0.00 microg/ml to 1.18 +/- 0.21 microg/ml during 120 min of recirculation. Human neutrophil elastase release at 120 min was significantly inhibited in the presence of DUP 714 to 37% of the value with heparin alone. These results indicated that addition of this novel thrombin (and kallikrein) inhibitor to heparin preserved platelet counts, decreased platelet secretion, and provided the additional benefit of partially blocking neutrophil activation during simulated extracorporeal circulation.
In Edmunds et al. J Lond Math Soc 78(2):65–84,
2008
, a representation of a compact linear operator
acting between reflexive Banach spaces
and
with strictly convex duals was established in terms of ...elements
projections
of
onto subspaces
which are such that
and linear projections
satisfying
where the coefficients
are given explicitly. If
and the condition
is satisfied, the representation reduces to an analogue of the Schmidt representation of
when
and
are Hilbert spaces, and also
is a Schauder basis of
; thus condition (A) can not be satisfied if
does not have the approximation property. In this paper we investigate circumstances in which (A) does or does not hold, and analyse the implications.
We have performed a search for neutral Higgs bosons produced in association with bottom quarks in p (p) over bar collisions, using 260 pb(-1) of data collected with the D0 detector in Run II of the ...Fermilab Tevatron Collider. The cross sections for these processes are enhanced in many extensions of the standard model (SM), such as in its minimal supersymmetric extension at large tan beta. The results of our analysis agree with expectations from the SM, and we use our measurements to set upper limits on the production of neutral Higgs bosons in the mass range of 90 to 150 GeV.
Data recorded by the D0 experiment at the Fermilab Tevatron Collider are analyzed to search for neutral Higgs bosons produced in association with b quarks. The search is performed in the ...three-b-quark channel using multijet-triggered events corresponding to an integrated luminosity of 5.2 fbsuper-1. In the absence of any significant excess above background, limits are set on the cross section multiplied by the branching ratio in the Higgs boson mass range 90 to 300 GeV, extending the excluded regions in the parameter space of the minimal supersymmetric standard model.
We present measurements of the cross sections for the two main production modes of single top quarks in p (p) over bar collisions at root s = 1.96 TeV in the Run II data collected with the DO ...detector at the Fermilab Tevatron Collider, corresponding to an integrated luminosity of 9.7 fb(-1). The s-channel cross section is measured to be sigma(p (p) over bar -> tb + X) = 1.10(-0.31)(+0.33) pb with no assumptions on the value of the t-channel cross section. Similarly, the t-channel cross section is measured to be sigma(p (p) over bar -> tqb + X) = 3.07(-0.49)(+0.54) pb. We also measure the s + t combined cross section as sigma(p (p) over bar -> tb + X, tqb + X) = 4.11(-0.55)(+0.60) ph and set a lower limit on the CKM matrix element vertical bar V-tb vertical bar> 0.92 at 95% C.L., assuming mt = 172.5 GeV. The probability to measure a cross section for the s channel at the observed value or higher in the absence of signal is 1.0 x 10(-4), corresponding to a significance of 3.7 standard deviations.
We present measurements of direct photon pair production cross sections using 8.5 fb(-1) of data collected with the D0 detector at the Fermilab Tevatron p (p) over bar collider. The results are ...presented as differential distributions of the photon pair invariant mass d sigma/dM(gamma gamma), pair transverse momentum d sigma/dp(T)(gamma gamma) azimuthal angle between the photons d sigma/d Delta(phi)(gamma gamma), and polar scattering angle in the Collins-Soper frame d sigma/d vertical bar cos theta*vertical bar. Measurements are performed for isolated photons with transverse momenta p(T)(gamma) > 18 (17) GeV for the leading (next-to-leading) photon in P-T, pseudorapidities vertical bar eta(gamma)vertical bar < 0.9, and a separation in eta-phi space Delta R-gamma gamma > 0.4. We present comparisons with the predictions from Monte Carlo event generators DIPHOX and RESBOS implementing QCD calculations at next-to-leading order, 2 gamma NNLO at next-to-next-to-leading order, and SHERPA using matrix elements with higher-order real emissions matched to parton shower.
...in some of the countries in our analysis, the advent of novel childhood vaccines (especially for infections with seasonal peaks, such as rotavirus, influenza and pneumococcal conjugate vaccines) ...may lead to reductions of beds in some wards in order to free resources for alternative uses in other wards, or other parts of the health care system.
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