Human resource development professionals in Higher Education are continually striving to develop efficient interventions to increase the capabilities of their leaders. As a result of evaluating ...feedback from an action learning (AL) programme designed and delivered in North West Higher Education Institutions in the UK for women in senior academic and professional service roles, we are able to share how AL can be utilised to transcend and supplement traditional leadership training. The article discusses the approach taken to support participants to develop vital leadership behaviours through the acquisition of critical questioning and reflective habits whilst developing strong supportive cross-institutional relationships with other higher education leaders.
American Catholics Hennesey, James J
1983, 1983-06-02, 19810101, Letnik:
724
eBook
Written by one of the foremost historians of American Catholicism, this book presents a comprehensive history of the Roman Catholic Church in America from colonial times to the present. Hennesey ...examines, in particular, minority Catholics and developments in the western part of the United States, a region often overlooked in religious histories.
The Bypass versus Angioplasty in Severe Ischaemia of the Leg-2 (BASIL-2) randomised controlled trial has shown that, for patients with chronic limb threatening ischaemia (CLTI) who require an ...infrapopliteal (IP) revascularisation a vein bypass (VB) first revascularisation strategy led to a 35% increased risk of major amputation or death when compared with a best endovascular treatment (BET) first revascularisation strategy. The study aims are to place the BASIL-2 trial within the context of the CLTI patient population as a whole and to investigate the generalisability of the BASIL-2 outcome data.
This was an observational, single centre prospective cohort study. Between 24 June 2014 and 31 July 2018, the BASIL Prospective Cohort Study (PCS) was performed which used BASIL-2 trial case record forms to document the characteristics, initial and subsequent management, and outcomes of 471 consecutive CLTI patients admitted to an academic vascular centre. Ethical approval was obtained, and all patients provided fully informed written consent. Follow up data were censored on 14 December 2022.
Of the 238 patients who required an infrainguinal revascularisation, 75 (32%) had either IP bypass (39 patients) or IP BET (36 patients) outside BASIL-2. Seventeen patients were initially randomised to BASIL-2. A further three patients who did not have an IP revascularisation as their initial management were later randomised in BASIL-2. Therefore, 95/471 (20%) of patients had IP revascularisation (16% outside, 4% inside BASIL-2). Differences in amputation free survival, overall survival, and limb salvage between IP bypass and IP BET performed outside BASIL-2 were not subject to hypothesis testing due to the small sample size. Reasons for non-randomisation into the trial were numerous, but often due to anatomical and technical considerations.
CLTI patients who required an IP revascularisation procedure and were subsequently randomised into BASIL-2 accounted for a small subset of the CLTI population as a whole. For a wide range of patient, limb, anatomical and operational reasons, most patients in this cohort were deemed unsuitable for randomisation in BASIL-2. The results of BASIL-2 should be interpreted in this context.
Field tests of corn co-expressing two new delta-endotoxins from Bacillus thuringiensis (Bt) have demonstrated protection from root damage by western corn rootworm (Diabrotica virgifera virgifera ...LeConte). The level of protection exceeds that provided by chemical insecticides. In the bacterium, these proteins form crystals during the sporulation phase of the growth cycle, are encoded by a single operon, and have molecular masses of 14 kDa and 44 kDa. Corn rootworm larvae fed on corn roots expressing the proteins showed histopathological symptoms in the midgut epithelium.
Objective : To design and describe an effective rehabilitation programme for use in an ongoing trial on the efficacy of multidisciplinary brain injury rehabilitation for moderately head injured ...military service members. Design : Treatment arm of a randomized control trial. Setting : US military tertiary care hospital inpatient rehabilitation programme. Patients : Sixty seven active duty military with moderate to severe TBI who were randomized to the treatment arm of the protocol. Intervention : Eight week rehabilitation programme combining group and individual therapies with an inpatient milieu-oriented neuropsychological focus. Group therapies included fitness, planning and organization, cognitive skills, work skills, medication, and milieu groups, and community re-entry outings. Individual therapy included neuropsychology, work therapy, occupational therapy, and speech and language pathology. Main outcome measures : Successful return to work and return to duty. Results : At 1 year follow-up, 64 patients returned to work (96%) and 66% (44/67) returned to duty. Conclusion : The described rehabilitation programme demonstrates one successful effort to rehabilitate active duty military service members with TBI who have the potential to return to duty.
Two crystalline protoxins from
Bacillus thuringiensis (Bt), Cry1Fa1 and Cry34Ab1/Cry35Ab1 (Cry1F, Cry34/35Ab1), were evaluated for efficacy against lepidopteran and coleopteran storage pests. Cry1F ...was tested against the lepidopterans
Sitotroga cerealella (Angoumois grain moth) and colonies of
Plodia interpunctella (Indian mealmoth) that are susceptible or resistant to Bt Cry1Ab and Cry1Ac toxins, Bt subspecies
entomocidus, and the commercial formulation Dipel
®. Cry1F was also tested against the coleopterans
Cryptolestes pusillus (flat grain beetle) and
Tribolium castaneum (red flour beetle). Cry34/35Ab1 was tested against
S. cerealella,
C. pusillus, and
T. castaneum, and against additional coleopteran storage pests, including
Tenebrio molitor (yellow mealworm),
Trogoderma variabile (warehouse beetle),
Oryzaephilus surinamensis (sawtoothed grain beetle),
Rhyzopertha dominica (lesser grain borer), and
Sitophilus oryzae (rice weevil). Strains of Bt-susceptible or -resistant
P. interpunctella generally were more sensitive to Cry1A protoxin or toxin than either Cry1F protoxin or Dipel. Despite difficulties with the bioassay of
S. cerealella larvae, the data suggest that Cry1F and Cry34/35Ab1 caused increased larval mortality, and a developmental delay was observed and no pupae emerged with 0.9% Cry1F. Neither Cry1F nor the corn rootworm-active toxin Cry34/35Ab1 significantly affected the biological parameters of the coleopteran species evaluated.
Background: Marathon running involves running long distances and is associated with a high prevalence of running-related injuries. The calf has been identified as one of the most commonly injured ...structures during running. Running training causes an overload on muscle and stimulates a physiological adaptation to create a training response. Specific adaptations in metabolic and physiological function of a muscle may be further achieved through specificity of exercise training. Resistance training programmes are commonly implemented to enhance specific muscle strength and endurance; and are effective methods of performance and injury prevention. While evidence-based guidelines for resistance training exist, it is unclear whether runners are routinely incorporating evidence-based resistance training into marathon training programmes. If runners are performing habitual resistance training, it is also unknown if the resistance training is of sufficient magnitude or intensity to induce dose-related responses in calf muscle structure or function. Aim: The aim of this study was to evaluate gastrocnemius muscle structure and function in marathon runners who performed habitual resistance training in addition to regular endurance training, compared to marathon runners who performed traditional endurance running training only. Specific Objectives: • To describe the demographic and training characteristics of habitually resistance-trained marathon runners and traditionally running-trained marathon runners. • To determine if there were differences in gastrocnemius endurance, power and flexibility between habitually resistance-trained marathon runners and traditionally running-trained marathon runners. • To evaluate if there were differences in the gastrocnemius muscle structure and architecture in habitually resistance-trained marathon runners compared to traditionally running-trained marathon runners. • To establish if there were any differences in the number of calf injuries sustained in habitually resistance-trained marathon runners and traditionally running-trained marathon runners. Methods: Healthy male runners between 20 and 50 years were included in the study. Participants were required to have completed at least one marathon in the 12-month period prior to the study. Runners forming the "traditionally running-trained" group were required to be participating in regular endurance running training only. Runners in the "habitually resistance-trained group" were required to be performing resistance training in addition to regular endurance running training. Runners with any injury at the time of recruitment or runners who reported a calf injury within the six-month period prior to the study were excluded. Participants with any medical abnormalities detected during screening were also excluded from the study. Eight marathon runners participating in habitual resistance training plus standard running training and eleven marathon runners participating in traditional running training only were recruited for this study. Runners who met the criteria attended two testing sessions at least three days apart. During the first session, informed consent was obtained and the Physical Activity Readiness Questionnaire (PAR-Q) was completed to ensure participants could safely complete physical testing. A questionnaire was completed to determine relevant training and injury history. Body mass, height and the sum of seven skinfolds were recorded. Muscle architecture measurements, including fascicle length, pennation angle, thickness and volume, were performed via imaging ultrasound. Participants were then familiarised with the physical testing procedures. In the second testing session, calf muscle flexibility and endurance were assessed; and isokinetic testing was performed for the left and right triceps surae. Results: There were no significant differences in descriptive characteristics between groups. Participants in the habitually resistance-trained group performed in an average of two hours (range 0.5-2.5 hours) of resistance training of between one to four sessions per week. Participants combined upper and lower body training in the form of circuit training, body weight training, core and proprioceptive training. Resistance training sessions were performed at a varied intensity for load (light to high) according to an estimated 1RM. Participants in the habitually resistancetrained group had completed a significantly greater number of 21.1 km races compared to the traditionally running-trained group (p < 0.05); but there were no other differences in running training or competition history between groups. There were also no significant differences in the number of reported injuries between groups. Average pennation angle was significantly increased in the habitually resistance-trained group compared to the traditional running-trained group (p < 0.05). No other significant differences in architectural measurements were identified. There were no significant differences in calf muscle flexibility, strength, power or endurance between the two groups. However, the small sample size limits the interpretation of the study findings. Conclusion: Wide variability in habitual resistance training patterns were identified. While pennation angle was significantly greater in the habitually resistance-trained group; no differences in all other architectural measurements; or calf muscle strength, power, endurance or flexibility between groups were identified. However, one of the key findings emerging from this study is the variable resistance training practices in endurance runners; and that resistance training practices were not aligned to current evidence-based guidelines for resistance training. Resistance training has a critical role in enhancing endurance running performance, injury prevention and rehabilitation. Future research should investigate the knowledge, attitudes and practices of endurance runners regarding resistance training; to facilitate the development of appropriate education interventions, and to effectively disseminate evidence-based training guidelines to lay communities.
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