•A multidisciplinary lab was created to test surgical masks due to COVID outbreak.•435 mask prototypes were tested during the emergency according to the EU standard.•Masks were analyzed according to ...the material and the number of layers.•A control of aerosol droplet size in the bacterial filtration was found critical.•The standard norm protocols are discussed and best practices are provided.
The outbreak of SARS-CoV-2 pandemic highlighted the worldwide lack of surgical masks and personal protective equipment, which represent the main defense available against respiratory diseases as COVID-19. At the time, masks shortage was dramatic in Italy, the first European country seriously hit by the pandemic: aiming to address the emergency and to support the Italian industrial reconversion to the production of surgical masks, a multidisciplinary team of the University of Bologna organized a laboratory to test surgical masks according to European regulations. The group, driven by the expertise of chemical engineers, microbiologists, and occupational physicians, set-up the test lines to perform all the functional tests required. The laboratory started its activity on late March 2020, and as of the end of December of the same year 435 surgical mask prototypes were tested, with only 42 masks compliant to the European standard. From the analysis of the materials used, as well as of the production methods, it was found that a compliant surgical mask is most likely composed of three layers, a central meltblown filtration layer and two external spunbond comfort layers. An increase in the material thickness (grammage), or in the number of layers, does not improve the filtration efficiency, but leads to poor breathability, indicating that filtration depends not only on pure size exclusion, but other mechanisms are taking place (driven by electrostatic charge).
The study critically reviewed the European standard procedures, identifying the weak aspects; among the others, the control of aerosol droplet size during the bacterial filtration test results to be crucial, since it can change the classification of a mask when its performance lies near to the limiting values of 95 or 98%.
The relationship between protein Z levels and thrombosis is controversial. We performed a systematic review and meta-analysis of the available studies to assess the association between protein Z and ...vascular thrombotic diseases. We conducted an electronic literature search through MedLine, Embase, Google Scholar, Web of Science, The Cochrane Library, bibliographies of retrieved articles and abstracts of congresses up to October, 2009. Studies were included if they analysed protein Z levels in patients with vascular thrombotic diseases. After the review process, 28 case-control studies (33 patient cohorts), including 4,218 patients with thrombotic diseases and 4,778 controls, were selected for analysis. The overall analysis using a random-effects model showed that low protein Z levels were associated with an increased risk of thrombosis (odds ratio OR 2.90, 95% confidence interval CI 2.05-4.12; p<0.00001). On subgroup analysis, a significant association was found between low protein Z levels and arterial vascular diseases (OR 2.67, 95%CI 1.60-4.48; p=0.0002), pregnancy complications (OR 4.17, 95%CI 2.31-7.52; p<0.00001), and venous thromboembolic diseases (OR 2.18, 95%CI 1.19-4.00; p=0.01). The results of this meta-analysis are consistent with a role for protein Z deficiency in thrombotic diseases, including arterial thrombosis, pregnancy complications and venous thromboembolism.
CERN has been building a transportable RFQ for use in the examination of art masterpieces based mainly on the PIXE (Proton Induced X-ray Emission) technique with an extracted beam. This new PIXE-RFQ ...accelerator is very compact, only one meter in length with a power consumption of less than 6 kVA for a beam energy of 2 MeV and an average current of 5 nA. The PIXE-RFQ will be used for the MACHINA (Movable Accelerator for Cultural Heritage In-situ Non-destructive Analysis) project developed jointly by CERN and INFN. This paper will present the detailed design and performances of the PIXE-RFQ as well as the fabrication technologies used and the current status of the project. The beam size and the peak current/duty cycle of the RFQ have been optimised for the Ion Beam Analysis (IBA) of artwork objects.
ABSTRACT
A complex aeromagnetic anomaly in Southern Apennines (Italy) is analysed and interpreted by a multiscale method based on the scaling function. We use multiscale methods allowing analysis of ...a potential field along ridges, which are lines defined by the position of the extrema of the field at the considered scales. The method developed and applied in this paper is based on the study of the scaling function of the total magnetic field. It allows recovering of source parameters such as depth and structural index. The studied area includes a Pleistocene volcanic structure (Mt. Vulture) whose intense dipolar anomaly is superimposed on a longer wavelength regional anomaly. The interpretation of ridges of the modulus of the analytic signal at different altitude ranges allows recognition of at least three distinct sources between about 5 km and 20 km depth. Their interpretation is discussed in light of borehole data and other geophysical constraints. A reasonable geological model for these sources indicates the presence of intrusions, probably linked to the past activity of Mt. Vulture.
This work will present preliminary results concerning the use of time-resolved ion beam induced luminescence applied to provenance studies of lapis lazuli. Measurements were performed at the pulsed ...beam facility at LABEC laboratory in Florence. Lapis lazuli is a semi-precious gemstone, used as ornament since the early civilizations that can be found in few places on Earth. The importance of this work lies in understanding the origin of various samples of lapis lazuli, from which it may be possible to gain insight into trade routes from ancient times. The samples studied in this work originated from Chile, Afghanistan, Tajikistan, Myanmar, and Siberia. The stones were irradiated with 3MeV protons and the resulting luminescence was detected by a photomultiplier tube, whose output was acquired using a sampling digitizer VME module (CAEN/V1720). Wavelength discrimination was performed at 430nm utilizing a range of beam currents. The results showed that, by changing the beam current intensity, one can study different features of lapis lazuli, and this may aid in distinguishing lapis lazuli from different provenances.
In this paper, we present a new Bouguer gravity map of the Northern Tuscan offshore (central Italy), based on original gravity data acquired on the islands of the Tuscan Archipelago. Our dataset ...integrates 274 unpublished gravity field measurements with 126 available marine gravity data of the northern Tyrrhenian Sea. The Bouguer anomaly map shows a westward and southward increase of the regional gravity field associated with the uplift of the Moho boundary from central Apennines towards the Tyrrhenian Sea. At a local scale, several Bouguer anomalies are well associated with the igneous plutons of the Elba, Montecristo and Capraia islands, as a result of a deep density contrast between the granitoid intrusive rocks and the embedding metamorphic basement. The presented Bouguer anomaly map represents a useful tool for future studies of the complex geological and geodynamical setting of the Tuscan Archipelago and of the buried and deep igneous structures.
A high‐resolution method to image the horizontal boundaries of gravity and magnetic sources is presented (the enhanced horizontal derivative (EHD) method). The EHD is formed by taking the horizontal ...derivative of a sum of vertical derivatives of increasing order. The location of EHD maxima is used to outline the source boundaries. While for gravity anomalies the method can be applied immediately, magnetic anomalies should be previously reduced to the pole. We found that working on reduced‐to‐the‐pole magnetic anomalies leads to better results than those obtainable by working on magnetic anomalies in dipolar form, even when the magnetization direction parameters are not well estimated. This is confirmed also for other popular methods used to estimate the horizontal location of potential fields source boundaries.
The EHD method is highly flexible, and different conditions of signal‐to‐noise ratios and depths‐to‐source can be treated by an appropriate selection of the terms of the summation. A strategy to perform high‐order vertical derivatives is also suggested. This involves both frequency‐ and space‐domain transformations and gives more stable results than the usual Fourier method.
The high resolution of the EHD method is demonstrated on a number of synthetic gravity and magnetic fields due to isolated as well as to interfering deep‐seated prismatic sources. The resolving power of this method was tested also by comparing the results with those obtained by another high‐resolution method based on the analytic signal. The success of the EHD method in the definition of the source boundary is due to the fact that it conveys efficiently all the different boundary information contained in any single term of the sum.
Application to a magnetic data set of a volcanic area in southern Italy helped to define the probable boundaries of a calderic collapse, marked by a number of magmatic intrusions. Previous interpretations of gravity and magnetic fields suggested a subcircular shape for this caldera, the boundaries of which are imaged with better detail using the EHD method.
We describe a multiscale method to estimate the excess mass of gravity anomaly sources, based on the theory of source moments. Using a multipole expansion of the potential field and considering only ...the data along the vertical direction, a system of linear equations is obtained. The choice of inverting data along a vertical profile can help us to reduce the interference effects due to nearby anomalies and will allow a local estimate of the source parameters. A criterion is established allowing the selection of the optimal highest altitude of the vertical profile data and truncation order of the series expansion. The inversion provides an estimate of the total anomalous mass and of the depth to the centre of mass. The method has several advantages with respect to classical methods, such as the Gauss’ method: (i) we need just a 1-D inversion to obtain our estimates, being the inverted data sampled along a single vertical profile; (ii) the resolution may be straightforward enhanced by using vertical derivatives; (iii) the centre of mass is also estimated, besides the excess mass; (iv) the method is very robust versus noise; (v) the profile may be chosen in such a way to minimize the effects from interfering anomalies or from side effects due to the a limited area extension. The multiscale estimation of excess mass method can be successfully used in various fields of application. Here, we analyse the gravity anomaly generated by a sulphide body in the Skelleftea ore district, North Sweden, obtaining source mass and volume estimates in agreement with the known information. We show also that these estimates are substantially improved with respect to those obtained with the classical approach.
The problem of finite-size effects in s=1/2 Ising systems showing slow dynamics of the magnetization is investigated introducing diamagnetic impurities in a Co2+-radical chain. The static magnetic ...properties have been measured and analyzed considering the peculiarities induced by the ferrimagnetic character of the compound. The dynamic susceptibility shows that an Arrhenius law is observed with the same energy barrier for the pure and the doped compounds while the prefactor decreases, as theoretically predicted. Multiple spin reversal has also been investigated.
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