Strong gravitational lensing (SL) is a powerful means to map the distribution of dark matter. In this work, we perform a SL analysis of the prominent X-ray cluster RXJ0152.7-1357 (z=0.83, also known ...as CL 0152.7-1357) in \textit{Hubble Space Telescope} images, taken in the framework of the Reionization Lensing Cluster Survey (RELICS). On top of a previously known \(z=3.93\) galaxy multiply imaged by RXJ0152.7-1357, for which we identify an additional multiple image, guided by a light-traces-mass approach we identify seven new sets of multiply imaged background sources lensed by this cluster, spanning the redshift range 1.79-3.93. A total of 25 multiple images are seen over a small area of ~0.4 \(arcmin^2\), allowing us to put relatively high-resolution constraints on the inner matter distribution. Although modestly massive, the high degree of substructure together with its very elongated shape make RXJ0152.7-1357 a very efficient lens for its size. This cluster also comprises the third-largest sample of z~6-7 candidates in the RELICS survey. Finally, we present a comparison of our resulting mass distribution and magnification estimates with those from a Lenstool model. These models are made publicly available through the MAST archive.
Mechanical stretch induces an increase in Na + influx into myocytes, related to mechanisms including stretch-activated channels or activation of Na+/H+ exchanger, involving changes in ...electrophysiological properties favouring arrhythmia induction. The aim of this study is to investigate the effects of mechanical stretch in cultured atrial murine cells (HL-1 myocytes) and its pharmacological response to ranolazine. Confluent HL-1 myocytes with spontaneous fibrillatory activity was cultured in silicone membrane plates, and were stretched to 110% of resting length. The response to stretch under control conditions and under ranolazine effects was analyzed using a high-resolution optical mapping system. HL-1 cells stretching increased atrial fibrillation dominant frequency in control conditions. The administration of ranolazine reduced this stretch-induced effect, and slowed the arrhythmia in baseline conditions. Ranolazine attenuates the modifications of electrophysiological effects induced by myocardial stretch in HL-1 cells model of AF.
We present a lens model for the cluster SPT-CLJ0615\(-\)5746, which is the highest redshift (\(z=0.972\)) system in the Reionization of Lensing Clusters Survey (RELICS), making it the highest ...redshift cluster for which a full strong lens model is published. We identify three systems of multiply-imaged lensed galaxies, two of which we spectroscopically confirm at \(z=1.358\) and \(z=4.013\), which we use as constraints for the model. We find a foreground structure at \(z\sim0.4\), which we include as a second cluster-sized halo in one of our models; however two different statistical tests find the best-fit model consists of one cluster-sized halo combined with three individually optimized galaxy-sized halos, as well as contributions from the cluster galaxies themselves. We find the total projected mass density within \(r=26.7"\) (the region where the strong lensing constraints exist) to be \(M=2.51^{+0.15}_{-0.09}\times 10^{14}\)~M\(_{\odot}\). If we extrapolate out to \(r_{500}\), our projected mass density is consistent with the mass inferred from weak lensing and from the Sunyaev-Zel'dovich effect (\(M\sim10^{15}\)~M\(_{\odot}\)). This cluster is lensing a previously reported \(z\sim10\) galaxy, which, if spectroscopically confirmed, will be the highest-redshift strongly lensed galaxy known.
Massive foreground galaxy clusters magnify and distort the light of objects behind them, permitting a view into both the extremely distant and intrinsically faint galaxy populations. We present here ...the z ~ 6 - 8 candidate high-redshift galaxies from the Reionization Lensing Cluster Survey (RELICS), a Hubble and Spitzer Space Telescope survey of 41 massive galaxy clusters spanning an area of ~200 arcmin^2. These clusters were selected to be excellent lenses and we find similar high-redshift sample sizes and magnitude distributions as CLASH. We discover 321 candidate galaxies with photometric redshifts between z ~ 6 to z ~ 8, including extremely bright objects with H-band magnitudes of m_AB ~ 23 mag. As a sample, the observed (lensed) magnitudes of these galaxies are among the brightest known at z> 6, comparable to much wider, blank-field surveys. RELICS demonstrates the efficiency of using strong gravitational lenses to produce high-redshift samples in the epoch of reionization. These brightly observed galaxies are excellent targets for follow-up study with current and future observatories, including the James Webb Space Telescope.
Strong gravitational lensing by galaxy clusters magnifies background galaxies, enhancing our ability to discover statistically significant samples of galaxies at z>6, in order to constrain the ...high-redshift galaxy luminosity functions. Here, we present the first five lens models out of the Reionization Lensing Cluster Survey (RELICS) Hubble Treasury Program, based on new HST WFC3/IR and ACS imaging of the clusters RXC J0142.9+4438, Abell 2537, Abell 2163, RXC J2211.7-0349, and ACT-CLJ0102-49151. The derived lensing magnification is essential for estimating the intrinsic properties of high-redshift galaxy candidates, and properly accounting for the survey volume. We report on new spectroscopic redshifts of multiply imaged lensed galaxies behind these clusters, which are used as constraints, and detail our strategy to reduce systematic uncertainties due to lack of spectroscopic information. In addition, we quantify the uncertainty on the lensing magnification due to statistical and systematic errors related to the lens modeling process, and find that in all but one cluster, the magnification is constrained to better than 20% in at least 80% of the field of view, including statistical and systematic uncertainties. The five clusters presented in this paper span the range of masses and redshifts of the clusters in the RELICS program. We find that they exhibit similar strong lensing efficiencies to the clusters targeted by the Hubble Frontier Fields within the WFC3/IR field of view. Outputs of the lens models are made available to the community through the Mikulski Archive for Space Telescopes
Unusual complications after radical cystectomy Martínez Salamanca, Juan Ignacio; García Burgos, Juan; Subirá Ríos, David ...
Archivos españoles de urología
56, Številka:
5
Journal Article
Recenzirano
To report complications that are very rare in patients undergoing radical cystectomy and Bricker's ileal conduit. In accordance to the literature and our own experience, to remark the importance of a ...proper preoperative preparation (nutritional, preanesthetic evaluation...), and adequate postoperative controls to avoid this kind of problems.
We report three cases which are demonstrative of these complications, their main characteristics, as well as their diagnosis, treatment, and outcomes.
All three cases were complicated by fistulae, with different outcomes. The diagnostic measures undertook on each one are reviewed in detail. Although it is well shown in the literature that most of these fistulae appear in patients with intestinal inflammatory/infectious diseases, this was not our experience.
After a bibliographic review and study of our cases, we insist on the importance of a good nutritional evaluation before surgery, and that radical cystectomy with Bricker's type urinary diversion, although consolidated as treatment for infiltrative bladder cancer, is not exempt of immediate postoperative complications or even deferred, as in our case.
To evaluate which clinical variables are predictive for prostate cancer and possible relationships among them, in patients with elevated PSA and non suspicious digital rectal examination (DRE) ...undergoing first prostate biopsy.
1618 patients with elevated PSA and non suspicious DRE who underwent sextant peripheral prostate biopsy were selected from our database. PSA, age, prostate volume, and detectable nodule by ultrasound were selected as variables related to cancer detection in first and second biopsies.
Mean age was 67.5 +/- 7.4 (37-88) years, mean PSA was 16.9 +/- 116.5 (3.6-4500) ng\ml, mean prostate volume was 65.7 +/- 37.8 (8-352) cc. 23.3% patients presented a hypoechoic nodule within the peripheral zone of the gland. 18.8% presented prostate cancer on first biopsy. On multivariate analysis, age (p < 0.001), prostate volume (p < 0.001), and presence of a nodule on ultrasound (p = 0.003) were considered independent predictive variables for cancer detection on biopsy. Direct relationship with age, and inverse relationship with prostate volume were shown. Detection rates on second biopsy were greater in patients with prostates = 40 cc in comparison to those > 40 cc (p = 0.02). First two biopsies detected 95% of cancer cases, first three up to 98%.
Age and prostate volume should be taken into consideration when individualizing the number of cores to obtain at the time of biopsy. The efficacy of peripheral sextant biopsy in prostates = for 40 cc should be re-evaluated. Third and fourth biopsies should be reserved for patients with very adverse risk factors.
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