Pain as Yardstick: Jean Améry Ferber, Ilit
Journal of French and Francophone philosophy,
02/2017, Letnik:
24, Številka:
3
Journal Article
Recenzirano
Odprti dostop
One of the best known and most widely accepted premises regarding the experience of pain and suffering is its singular, private nature. Pain’s violence isolates us from everything else, embedding us ...completely within our own suffering so that there is nothing else but pain: no world or objects, no relationship with other people, no past or anticipation of the future. An utter withdrawal. But pain’s isolating force is dual: it affects not only those who suffer, but also those who are not in pain. Thus, it is precisely in pain – the exemplary state in which we need others with us to offer their help and sympathy – that we find ourselves in solitude; and it is precisely in the state of pain that we leave others to suffer alone.
This article unveils the geometric characteristics of boats with sails of many sizes, covering the range 10
-10
kg. Data from one hundred boat models are collected and tabulated. The data show ...distinct trends of convergent evolution across the entire range of sizes, namely: (i) the proportionality between beam and draft, (ii) the proportionality between overall boat length and beam, and (iii) the proportionality between mast height and overall boat length. The review shows that the geometric aspect ratios (i)-(iii) are predictable from the physics of evolution toward architectures that offer greater flow access through the medium.
To compare kinematics, kinetics and muscle activity during standing and walking for healthy subjects using an unstable test shoe (Masai Barefoot Technology, MBT) and a stable control shoe.
Eight ...subjects volunteered for this study. During quiet standing, center of pressure excursion and muscle activity were determined. During walking, lower extremity kinematics, kinetics, and muscle electromyographic (EMG) signals were determined. Data were collected for the two shoe conditions after a 2
week accommodation period. Statistics included repeated measures ANOVAs (
α
=
0.05) and post hoc tests where appropriate.
During quiet standing, the center of pressure excursion was significantly and substantially greater in the unstable compared to the control shoe. Electromyographic intensity increased in the unstable test shoe for all tested muscles, but only significantly for the tibialis anterior. During locomotion, kinematics were similar in the two shoe conditions except for the initial plantar–dorsiflexion, which showed a significant more dorsiflexed position during the first half of stance in the unstable test shoe compared to the stable control shoe. The angular impulses did not show any significant differences between the two shoe conditions for all three joints but some trends towards a reduction for the knee and hip joint. There were no significant differences in electromyographic activities between the control and the unstable shoe. However, several muscles showed some trends.
The unstable shoe produced changes and trends in kinematic, kinetic and electromyographic characteristics that seemed to be advantageous for the locomotor system. Further studies should investigate muscle strength, dynamic stability, pain reduction for arthritic knees and injury prevention for high performance athletes when using the unstable shoes.
Polymer conjugation is an efficient approach to improve the delivery of drugs and biological agents, both by protecting the body from the drug (by improving biodistribution and reducing toxicity) and ...by protecting the drug from the body (by preventing degradation and enhancing cellular uptake). This review discusses the journey that polymer therapeutics make through the body, following the ADME (absorption, distribution, metabolism, excretion) concept. The biological factors and delivery system parameters that influence each stage of the process will be described, with examples illustrating the different solutions to the challenges of drug delivery systems in vivo.
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Magnetic field (MF) non-ionizing radiation is widespread and everyone is exposed to some degree. This prospective cohort study of 913 pregnant women examined the association between high MF exposure ...and miscarriage risk. Cox (proportional hazards) regression was used to examine the association. After controlling for multiple other factors, women who were exposed to higher MF levels had 2.72 times the risk of miscarriage (hazard ratio = 2.72, 95% CI: 1.42-5.19) than those with lower MF exposure. The increased risk of miscarriage associated with high MF was consistently observed regardless of the sources of high MF. The association was much stronger if MF was measured on a typical day of participants' pregnancies. The finding also demonstrated that accurate measurement of MF exposure is vital for examining MF health effects. This study provides fresh evidence, directly from a human population, that MF non-ionizing radiation could have adverse biological impacts on human health.
Objective Racial disparities in health outcomes are a persistent threat in gentrifying neighborhoods. A contributor to health outcomes is health services utilization, the extent to which people ...receive care from a medical professional. There are documented racial disparities in health services utilization in the general population. We aim to determine whether racial disparities in health services utilization exist in gentrifying neighborhoods. Methods We used data from the American Community Survey to identify gentrifying neighborhoods across the United States from 2006 to 2017. We collected data on three measures of healthcare services utilization (office-based physician visits, office-based nonphysician visits, and having a usual source of care) for 247 Black and 689 White non-Hispanic respondents of the 2014 Medical Expenditure Panel Survey living in gentrifying neighborhoods. We used modified Poisson models to determine whether there is a difference in the prevalence of health services utilization by race among residents of gentrifying neighborhoods. Results After adjusting for age, gender, education, income, employment, insurance, marital status, region, and self-rated health, Black residents of gentrifying neighborhoods demonstrated a similar prevalence of having an office-based physician visit, a lower prevalence of having an office-based nonphysician visit (prevalence ratio: 0.74; 95% confidence interval, 0.60 to 0.91), and a lower prevalence of having a usual source of care (prevalence ratio: 0.87; 95% confidence interval, 0.77 to 0.98) than White residents. Conclusions The existence of racial disparities in health services utilization in US gentrifying neighborhoods demonstrates a need for policy-relevant solutions to create a more equitable distribution of health resources.
Forecasting dark showers at Belle II Bernreuther, Elias; Böse, Kai; Ferber, Torben ...
The journal of high energy physics,
1/12, Letnik:
2022, Številka:
12
Journal Article
Recenzirano
Odprti dostop
A
bstract
Dark showers from strongly interacting dark sectors that confine at the GeV scale can give rise to novel signatures at
e
+
e
−
colliders. In this work, we study the sensitivity of
B
factory ...experiments to dark showers produced through an effective interaction arising from a heavy off-shell mediator. We show that a prospective search for displaced vertices from GeV-scale long-lived particles at Belle II can improve the sensitivity to dark showers substantially compared to an existing search at BaBar. We compare the sensitivity of searches for displaced signals to searches for promptly produced resonances at BaBar and KLOE and calculate sensitivity projections for a single-photon search at Belle II to invisible dark showers produced through an effective interaction. The underlying structure of the effective interaction can be resolved at higher-energy experiments, where the mediator can be produced on-shell. To study the resulting constraints, we update electroweak precision bounds on kinetically mixed
Z
′ bosons and reinterpret a search for low-mass di-muon resonances at LHCb in terms of dark showers. We find that LHCb and Belle II are most sensitive to different particle decay lengths, underscoring the complementarity of LHC and intensity frontier experiments.
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