A prospective study of the ability of laboratory tests to detect or to exclude hepatic metastases was performed. Seventy-four patients who underwent liver biopsies were divided into 3 groups: 1) 33 ...patients with secondary liver involvement from adenocarcinoma; 2) 21 subjects suffering from a non-malignant hepatic disease, and 3) 20 cancerous patients free of overt hepatic metastases. They were investigated with 7 laboratory tests. No single test had a positive predictive value higher than 75%. This percentage was increased to 84% by combining the results of both CEA and rapidly migrating liver alkaline phosphatase isoenzyme ALP 1. More important was the fact that when those parameters were both normal, the negative predictive value was 93%, thus tending to exclude a liver metastatic involvement with an acceptable confidence limit.
Ruffié Th., P. Fernet M., Larrouy Georges. Étude biométrique du massif facial et de la denture des Amérindiens Aymara et des métis de l'Altiplano bolivien.. In: Bulletins et Mémoires de la Société ...d'anthropologie de Paris, XI° Série. Tome 9 fascicule 1, 1966. pp. 109-122.
Fernet P., Larrouy Georges, Ruffié Jacques. Étude hémotypologique des populations indiennes de Guyane française; II. les groupes sériques du système Gm.. In: Bulletins et Mémoires de la Société ...d'anthropologie de Paris, XI° Série. Tome 7 fascicule 1, 1965. pp. 119-123.
Cabannes R., Larrouy Georges, Fernet P., Sendrail A. Étude hémotypologique des populations sédentaires de la Saoura (Sahara occidental) ; II, Les hémoglobines . In: Bulletins et Mémoires de la ...Société d'anthropologie de Paris, XII° Série. Tome 4 fascicule 2, 1969. pp. 139-142.
Ducos J., Fernet P., Vergnes H. Étude hémotypologique des populations du Tidikelt ; les groupes sériques.. In: Bulletins et Mémoires de la Société d'anthropologie de Paris, XI° Série. Tome 7 ...fascicule 2, 1965. pp. 185-187.
Résumé La confrontation des marqueurs sanguins et des généalogies recueillis au Scoresbysund permet de conclure à l'exactitude des généalogies, exactitude prouvée par la quasi-absence d'anomalies de ...transmission dans les systèmes ABO, Gm, Inv et Hp. Par contre, de multiples anomalies observées dans les systèmes MN, P, et surtout concernant les facteurs E, e et с du système Rhésus, semblent, après examen détaillé, devoir s'expliquer par des erreurs dans la détermination des phénotypes. Ceci confirme l'intérêt majeur des groupes sériques, ou HLa, en anthropologie et en génétique des populations, l'étude des groupes érythrocytaires se révélant souvent de technique trop délicate et coûteuse pour être menée à bien sur des échantillons importants. De plus, ils n'apportent finalement qu'une information assez pauvre.
Summary Pedigrees and Blood Polymorphism of Scoresbysund Greenlanders Inheritance study of ABO, Gm, Inv and Hp blood markers confirms the available genealogical data. Detailed study of descent exclusions of Rh E, e, с and of N and P factors concludes to the existence of mistypings. These difficulties in red cell typing stress the outstanding interest of serie and HLa polymorphisms in population genetics and anthropology.
Langaney A., Robert-Lamblin Joëlle, Fernet P. Généalogies et polymorphismes sanguins des Groenlandais du Scoresbysund. In: Cahiers du Centre de recherches anthropologiques, XIII° Série. Tome 2 fascicule 1-4, 1974. pp. 147-152.
Fourteen HLA-A and 18 HLA-B antigens were studied in three samples of Pyrenean populations: 198 unrelated individuals of a "Pays Basque" group; 212 non-Basque individuals from a valley in Bearn, ...l'Ouzom; and 73 non-Basque individuals from the neighboring valley of Bareges. The results in the Basque and the non-Basque people from l'Ouzom were comparable: the gene frequencies of HLA-A29, Aw19.2, B17 were increased and the haplotypes HLA-Aw19.2, B18; A29, B12; A2, B5; A1, B17 were found frequently with a striking linkage disequilibrium; HLA-B18 had an increased gene frequency in all these Pyrenean populations, while Bw35 was frequent in l'Ouzom and Bareges, but not among the Basques. The characteristics of Bareges were very different: the gene frequencies of HLA-A2, A11, B7 were increased while the frequency of HLA-B5 was low; the most characteristic haplotypes were HLA-A2, B12; A2, B18; A11, Bw35; A11, B27. It is interesting to note discrepancies between ethnic and HLA classification of the Basques and the non-Basque population of l'Ouzom. The HLA characteristics are quite different in the Hareges sample, more closely resembling those of Northern Europe.
