Research Summary Just four decades ago, the predominant narrative in crime prevention and rehabilitation was that nothing works. Since that time, criminologists have accumulated a wide body of ...evidence about programs and practices in systematic reviews. In this article, we summarize what is known in seven broad criminal justice areas by drawing on 118 systematic reviews. Although not everything works, through our “review of reviews,” we provide persuasive evidence of the effectiveness of programs, policies, and practices across a variety of intervention areas. Policy Implications It is time to abandon the idea that “nothing works,” not only in corrections but also in developmental, community, and situational prevention; sentencing; policing; and drug treatment. Nevertheless, key gaps remain in our knowledge base. The results of systematic reviews should provide more specific guidance to practitioners. In many areas few randomized evaluations have been conducted. Finally, researchers, through their studies and systematic reviews, must pay more attention to cost–benefit analysis, qualitative research, and descriptive validity.
The essential features of total institutions include complete closure to the outside world and almost total surveillance of inmates within. All activities are concentrated in one place and under one ...authority. Inmates are condemned to a meticulously planned daily routine and their activities are carried out in pursuit of the institution’s goal. Finally, the model distinguishes between staff and inmates. The former are responsible for supervising the latter. According to Goffman, five different types of institutions can be distinguished. In addition to welfare institutions and institutions for the rational performance of certain work-like tasks (barracks, ship, boarding school), he calls prisons, asylums and monasteries total institutions. They serve to protect or rehabilitate the community, are havens from the world or places of contemplation, and provide healing or care for people who are unable to care for themselves and pose an unintended threat to others. Entry into the total institution involves a permanent loss of role through separation from the rest of the world. In addition, the newcomer must undergo a series of procedures that are seen as a profound break from the previous life. These include undressing and dressing in (institutional) clothing, which is imbued with symbolic meaning. This is the point of departure for this article, which seeks to answer the following research question: How does the clothing of monastic inmates, prison inmates and psychiatric patients differ both in terms of design and in terms of their supportive functions in the context of achieving the institutional goal?
The decomposition and its effects on the crystallization of the bulk metallic glass (MG) Zr sub 41 Ti sub 14 Cu sub 12.5 Ni sub 10 Be sub 22.5 has been investigated using transmission electron ...microscopy (TEM). It is found that the decomposition destabilizes the MG and makes the MG thermally less stable with respect to crystallization. The effects of the phase separation on the subsequent crystallization are discussed based on the microstructural characteristics of the MG.
Berlin is increasingly emerging as a hub of Arab intellectual life in Europe. In this first study of Arab culture to zoom in on the thriving metropolis, the contributors shed light on the dynamics of ...transformation with Arabs as agents, subjects, and objects of change in the spheres of politics, society and history, gender, demographics and migration, media and culture, and education and research. The kaleidoscopic character of the collection, embracing academic articles, essays, interviews and photos, reflects critical encounters in Berlin. It brings together authors from inter- and multidisciplinary fields and backgrounds and invites the readers into a much-needed conversation on contemporary transformations.
Basement membranes-(BM) influence polarization, differentiation, migration and proliferation of cell and play an important role in maintaining structural and functional tissue integrity. While BM ...alterations have been reported in various lesions (e.g. inflammation, tumors) of laryngeal-tracheal tissues, reports on radiogenic BM alterations are rare. External irradiation (IRR) of advanced head and neck tumors often includes "normal tissues" (tissues without cancer) of the larynx. In these normal tissues both single-cell damage (necrosis, apoptosis, functional cell death) and interstitial damage (edema, fibrosis, vascular alterations, cellular infiltrations) resulting in tissue remodeling can occur, depending on various IRR parameters. In this study, we set out to add to our knowledge on the phenotypic characterization of the radiogenic BM expression pattern in laryngo-tracheal tissues.
In 63 laryngo-tracheal specimens from Wistar rats, we investigated the laminin (LA) and collagen IV (CIV) expression profile and distribution pattern depending on the IRR dose (fractionated IRR, 2 Gy/day, up to a total dose of 20, 40, or 60 Gy), the time since IRR (6 months vs 12 months) and animal age (1 year vs 1.5 years) using immunohistochemical methods, semiquantitative assessment, and multivariate analysis.
In specimens irradiated with more than 20 Gy, both BM constituents predominantly showed dose-dependent increases and sometimes fluctuations in staining at slight to moderate levels. The expression differed in frequency and level among the various tissue structures. In some structures there was decreased expression. In the vocalis muscle, laryngeal and esophageal nerve endings, recurrent laryngeal nerve and laryngeal and tracheal muscles, LA was detected at levels significantly stronger than in controls. BM surrounding gland structures, nerve endings of the piriform sinus and esophageal muscles showed a marked tendency towards increased LA expression. However, the BM underlying the mucosal layer of the supra- and subglottic region revealed decreasing LA immunoreaction up to 40 Gy IRR, but a distinct increase in expression at 60 Gy. In the esophageal and tracheal muscles, tracheal perichondrium, recurrent laryngeal nerve and capillaries, CIV was detected at significantly stronger levels than in the controls. The vocal ligament exhibited positive CIV immunoreactions adjacent to interstitial and infiltrate cells and CIV-positive BM condensations, resulting in increased staining of these structures. CIV reactions of laryngeal and hypopharyngeal nerve endings tended towards increased expression. In contrast, BM staining surrounding vocal muscle cells revealed significantly decreased expression. In addition, there was a tendency towards decreased expression for supraglottic, subglottic and hypopharyngeal muscle cells. Age and time since irradiation had no significant effect on staining.
The BM constituents laminin and collagen IV showed prominent dose-dependent increases and sometimes fluctuations in expression. This expression pattern persisted up to one year after completion of the irradiation. Thus, these findings must be related to late radiation effects. The altered BM expression may play a role, at least in part, in structural (e.g. laryngeal edema) and functional (voice disorders) changes associated with irradiation of the head and neck area.
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