3D MODEL OF BUILDING BASED ON MULTI-SOURCE DATA FUSION Wang, Y.; Huang, X.; Gao, M.
International archives of the photogrammetry, remote sensing and spatial information sciences.,
10/2022, Letnik:
XLVIII-3/W2-2022
Journal Article, Conference Proceeding
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Odprti dostop
The process of building a digital city is the construction of a three-dimensional city model. The construction of 3 d data model is the process of multi-source spatial information collection and ...fusion. The current means of spatial information collection are mainly divided into three-dimensional laser technology and UAV photogrammetry technology. The three-dimensional laser technology is mainly based on ground laser, which has high acquisition accuracy for the bottom part of the building, but it is insufficient for the information collection at the top of the building. UAV photogrammetry has a large area and high efficiency spatial information collection method. At the same time, a large three-dimensional city model of the building can also be constructed. However, due to practical problems such as flight height and ground occlusion, the model constructed by UAV photogrammetry has a perfect top and poor bottom quality. The two methods are combined to build a more perfect point cloud model. Aiming at the above problems, a three-dimensional modeling method of buildings under multi-source data fusion is proposed. Firstly, the point cloud data and image data obtained by 3D laser scanner and UAV are preprocessed, and the two data forms are transformed into high-precision point cloud data. Then two sets of point cloud data are fused to generate the whole point cloud data. Finally, based on the patch generated by the whole point cloud, the point cloud model is reverse modeled. Get the corresponding building entity model, in order to get a more perfect 3D city model.
With multiple elements mixed at equal or near-equal molar ratios, the emerging, high-entropy alloys (HEAs), also named multi-principal elements alloys (MEAs), have posed tremendous challenges to ...materials scientists and physicists, e.g., how to predict high-entropy phase formation and design alloys. In this paper, we propose some guidelines in predicting phase formation, using thermodynamic and topological parameters of the constituent elements. This guideline together with the existing ones will pave the way toward the composition design of MEAs and HEAs, as well as property optimization based on the composition–structure–property relationship.
Core/shell structured magnetic silica microspheres with immobilized Fe3+ (see image) are prepared with a simple method. Using a magnetic field, the microspheres are quickly, efficiently, and ...specifically enriched. Phosphopeptide identification can then be achieved through mass spectroscopy. This is a new method for the enrichment of phosphopeptides and opens up the possibility of other new applications using the microspheres.
We studied the phylogeography of Chinese yew (Taxus wallichiana), a tree species distributed over most of southern China and adjacent regions. A total of 1235 individuals from 50 populations from ...China and North Vietnam were analysed for chloroplast DNA variation using polymerase chain reaction-restriction fragment length polymorphism of the trnL-F intron-spacer region. A total of 19 different haplotypes were distinguished. We found a very high level of population differentiation and a strong phylogeographic pattern, suggesting low levels of recurrent gene flow among populations. Haplotype differentiation was most marked along the boundary between the Sino-Himalayan and Sino-Japanese Forest floristic subkingdoms, with only one haplotype being shared among these two subkingdoms. The Malesian and Sino-Himalayan Forest subkingdoms had five and 10 haplotypes, respectively, while the relatively large Sino-Japanese Forest subkingdom had only eight. The strong geography-haplotype correlation persisted at the regional floristic level, with most regions possessing a unique set of haplotypes, except for the central China region. Strong landscape effects were observed in the Hengduan and Dabashan mountains, where steep mountains and valleys might have been natural dispersal barriers. The molecular phylogenetic data, together with the geographic distribution of the haplotypes, suggest the existence of several localized refugia during the last glaciation from which the present-day distribution may be derived. The pattern of haplotype distribution across China and North Vietnam corresponded well with the current taxonomic delineation of the three intraspecific varieties of T. wallichiana.
The occupational health issues of shift workers has received increasing attention in the field of occupational health, and discussed in this article through literature review on the health risks and ...management of shift work both domestically and internationally. Based on this, a series of impacts of shift work on the physiological and psychological health of workers, as well as their family and social life, are revealed. Combined with relatively mature regulations and policies in foreign countries, it is proposed that China should fully learn from the relevant experience of health management in shift work abroad, Strengthen research and explore effective management intervention measures to provide ideas for accelerating the development of scientifically feasible regulations and policies related to occupational health in shift work in China.
RET fusions are present in 1%-2% of non-small-cell lung cancer (NSCLC). Pralsetinib, a highly potent, oral, central nervous system-penetrant, selective RET inhibitor, previously demonstrated clinical ...activity in patients with RET fusion–positive NSCLC in the phase I/II ARROW study, including among treatment-naive patients. We report an updated analysis from the ARROW study.
ARROW is a multi-cohort, open-label, phase I/II study. Eligible patients were ≥18 years of age with locally advanced or metastatic solid tumours and an Eastern Cooperative Oncology Group performance status of 0-2 (later 0-1). Patients initiated pralsetinib at the recommended phase II dose of 400 mg once daily until disease progression, intolerance, consent withdrawal, or investigator’s decision. The co-primary endpoints (phase II) were overall response rate (ORR) by blinded independent central review and safety.
Between 17 March 2017 and 6 November 2020 (data cut-off), 281 patients with RET fusion–positive NSCLC were enrolled. The ORR was 72% 54/75; 95% confidence interval (CI) 60% to 82% for treatment-naive patients and 59% (80/136; 95% CI 50% to 67%) for patients with prior platinum-based chemotherapy (enrolment cut-off for efficacy analysis: 22 May 2020); median duration of response was not reached for treatment-naive patients and 22.3 months for prior platinum-based chemotherapy patients. Tumour shrinkage was observed in all treatment-naive patients and in 97% of patients with prior platinum-based chemotherapy; median progression-free survival was 13.0 and 16.5 months, respectively. In patients with measurable intracranial metastases, the intracranial response rate was 70% (7/10; 95% CI 35% to 93%); all had received prior systemic treatment. In treatment-naive patients with RET fusion–positive NSCLC who initiated pralsetinib by the data cut-off (n = 116), the most common grade 3-4 treatment-related adverse events (TRAEs) were neutropenia (18%), hypertension (10%), increased blood creatine phosphokinase (9%), and lymphopenia (9%). Overall, 7% (20/281) discontinued due to TRAEs.
Pralsetinib treatment produced robust efficacy and was generally well tolerated in treatment-naive patients with advanced RET fusion–positive NSCLC. Results from the confirmatory phase III AcceleRET Lung study (NCT04222972) of pralsetinib versus standard of care in the first-line setting are pending.
•Pralsetinib produced an ORR of 72% in treatment-naive patients with RET fusion–positive NSCLC.•Pralsetinib was generally well tolerated and there were no new safety signals.•The confirmatory phase III AcceleRET Lung study (NCT04222972) of pralsetinib versus standard of care in the first-line setting is ongoing
Aim To analyse the computed tomography (CT) imaging features of patients with adrenal schwannoma. Materials and methods Eight cases of adrenal schwannoma confirmed by histopathology were included in ...this study. All eight patients had undergone multiphase CT examinations. The features of the adrenal schwannoma in the CT images were analysed retrospectively in detail, including size, shape, margin, radiodensity, calcification, and enhancement pattern. Results There were six male and two female patients, with a median age of 44.5 years (range, 25–52 years). Two patients complained of right flank pain, and two with left upper abdominal discomfort, while the remaining patients were diagnosed by routine ultrasound examinations. On unenhanced CT images, all cases of adrenal schwannoma were well circumscribed, rounded or oval, heterogeneous masses with cystic components, with two cases exhibiting calcification, and three cases with septa. On enhanced CT images, all cases displayed mild heterogeneous enhancement of the tumour during the arterial phase, and progressive enhancement during the portal venous phase and equilibrium phase. Conclusion Adrenal schwannoma commonly presents as a well-defined unilateral mass with cystic degeneration, septa, and a characteristic progressive contrast-enhancement pattern on multiphase enhanced scans.
Abstract Although siRNAs have surpassed expectations in experiments to alter gene expression in vitro , the lack of an efficient in vivo delivery system still remains a challenge in siRNA ...therapeutics development and has been recognized as a major hurdle for clinical applications. In this paper we describe an inorganic nanoparticle-based delivery system that is readily adaptable for in vivo systems. Layered double hydroxide (LDH) nanoparticles, a family of inorganic crystals, tightly bind, protect, and release siRNA molecules and deliver them efficiently to mammalian cells in vitro . The uptake of siRNA-loaded LDH nanoparticles occurs via endocytosis, whereby the nanoparticles dissolve due to the low pH in the endosome, thereby aiding endosomal escape into the cytoplasm. The influence of LDH nanoparticles on cell viability and proliferation is negligible at concentrations ≤0.050 mg mL−1 , and a pronounced down-regulation of protein expression upon LDH mediated siRNA transfection of HEK293T cells is observed.
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