We study the CPT-even dimension-six Chern–Simons-like term by including dynamical Kalb–Ramond and scalar fields to examine the cosmological birefringence. We show that the combined effect of a ...neutrino current and a Kalb–Ramond field could induce a sizable rotation polarization angle in the cosmic microwave background radiation polarization.
Objective: The effect and safety of etoposide combined with G-CSF were compared with those of cyclophosphamide combined with G-CSF in autologous peripheral blood mobilization in patients with ...multiple myeloma (MM) . Methods: Patients with MM who received autologous peripheral blood stem cell mobilization and collection in the Department of Hematology, Beijing Chaoyang Hospital Affiliated to Capital Medical University from January 1, 2020 to July 31, 2023 were included. A total of 134 patients were screened by propensity score matching technology according to a 1∶1 ratio. A total of 67 cases were each treated with ETO combined with G-CSF mobilization scheme (ETO group) and CTX combined with G-CSF mobilization scheme (CTX group). Their clinical data were retrospectively analyzed. Results: ①Collection results: the ETO and CTX groups 2 (1-3) d vs 2 (1-5) d; P<0.001 and CD34(+) cells 7.62×10(6) (2.26×10(6)-37.20×10(6)) /kg vs 2.73×10(6) (0.53×10(6)-9.85×10(6)) /kg; P<0.001 were collected. The success rate of c
The Mg-xGd (x = 4–16, wt%) alloys with columnar crystals were prepared by directional solidification, and the effect of Gd content on the crystal orientation, microstructure, and tensile properties ...at room temperature were studied. The microstructure of the Mg-4Gd alloy is single α-Mg solid solution, and the microstructure of the Mg-6Gd alloy is composed of α-Mg and Mg24Gd distributed along the longitudinal grain boundaries of columnar crystals, while the microstructure of the Mg-(8−16)Gd alloys consists of α-Mg and lamellar eutectic phase. The Mg-4Gd alloy with growth orientation concentrated in< 112(_)0 > (hard orientation) has high yield strength (186 MPa) and moderate elongation (12 %), because {101(_)1} compression twinning are activated to coordinate strain. However, the Mg-6Gd alloy with growth orientation concentrated in<1(_)21(_)2 > (soft orientation) has excellent elongation (38 %), as a result of activated {101(_)2} tension twinning. When the Gd content exceeds 12 %, plenty of eutectic phases will cause low strength and poor plasticity of the Mg-Gd alloys.
•The Mg-xGd alloys with columnar crystals were prepared by directional solidification.•The research further discussed the correlation of crystal orientation and mechanical properties of the Mg-Gd alloys.•{101(_)1} compression twinning and {101(_)2} tension twinning are important to improve grain boundary strain coordination.
Chronic subcutaneous infection due to Lichtheimia ramosa Geng, C.; Lv, X.; Li, J. ...
Journal of the European Academy of Dermatology and Venereology,
January 2019, 2019-Jan, 2019-01-00, Letnik:
33, Številka:
1
Journal Article
We study the matter–antimatter asymmetry through the leptogenesis mechanism in a specific model with the Friedberg–Lee (FL) symmetry. We relate the leptogenesis with the CP violating Dirac and ...Majorana phases in the Maki–Nakagawa–Sakata leptonic mixing matrix and illustrate the net baryon asymmetry of the universe in terms of these phases.
Transgenic maize plants expressing dsRNA targeting western corn rootworm (WCR, Diabrotica virgifera virgifera LeConte) v‐ATPase subunit C mRNA for RNAi provided significant root protection from WCR ...larval feeding damage in greenhouse assays compared to negative controls. Transcribed hairpin dsRNA in WCR‐resistant maize plants was present as both intact hairpin‐derived dsRNA and plant‐processed siRNA. Therefore, the ability of dsRNA and siRNA targeting Dv v‐ATPase CmRNA to cause an RNAi response was studied in both WCR larvae and adults. In 9‐day diet‐based feeding assays, dsRNA of at least 60 bp in length resulted in high levels of larval mortality. In contrast, 15‐, 25‐ or 27‐bp dsRNAs or pooled 21‐bp siRNAs did not cause mortality of exposed larvae. When larvae were fed with diet overlaid with siRNAs, Dv v‐ATPase C transcript levels did not change. Conversely, when WCR larvae were fed with diet overlaid with 184‐bp dsRNA, the mRNA level was reduced by >20‐fold relative to yfp dsRNA negative control. Similarly, 184‐bp dsRNA caused 100% mortality of WCR adults, whereas the mortality of adults fed on diet treated with siRNAs was similar to the negative control. Feeding adults with siRNAs on diet did not affect the level of Dv v‐ATPase CmRNA transcripts, whereas adults fed with the 184‐bp dsRNA showed approximately 35‐fold reduction in the target mRNA level. Similar results were obtained with the WCR adults injected with 184‐bp dsRNA or 21‐bp siRNA. These results suggest that only long dsRNA or hairpin‐derived dsRNA is effective in causing lethal knock‐down of Dv v‐ATPase CmRNA. These results have implications for efficacious plant‐delivered dsRNA for the protection of transgenic maize from WCR feeding damage and for the risk assessment of transgenic maize expressing insecticidal dsRNA.
Birth cohort studies of developmental defects of enamel (DDE) and early childhood caries (ECC) in very low birthweight (VLBW) and normal birthweight (NBW) infants are rare. In this birth cohort of ...234 VLBW and 234 NBW infants, we report the incidence of ECC and DDE at 8 and 18-20 mos of corrected age. Infant medical and maternal socio-demographic data were abstracted from medical records at birth. Dental assessments for ECC and DDE (enamel hypoplasia, demarcated and diffuse opacities) were completed at 8 and 18-20 mos. The incidence of hypoplasia was significantly higher in VLBW compared with NBW infants (8 mos, 19% vs. 2%; 18 mos, 31% vs. 8%). The incidence of ECC (International Caries Detection and Assessment System: ICDAS ≥ 2) was 1.4% (8 mos) and 12% (18-20 mos) and was similar between the VLBW and NBW groups. At both ages, using a beta-binomial regression model to control for potential confounders (maternal and infant characteristics), we found increased risk for enamel hypoplasia among the VLBW infants compared with the NBW infants. African Americans had a lower risk for enamel hypoplasia at 18-20 mos. The VLBW infants should be monitored for ECC due to the presence of enamel hypoplasia.
Grain orientation and deformation strain rate have impact on mechanical behaviors of magnesium alloys through their effect on the deformation modes. In this paper, uniaxial tensile tests were ...conducted at room temperature under various strain rates, from 2.8×10−5s−1 to 1.1×10−1s−1, on two kinds of AZ31B magnesium alloy samples which possess fiber texture and spread texture, respectively. It was found that the flow stress–strain curves of the samples with the fiber texture show a concave down shape and a yielding stress higher than that of the samples with the spread texture. The samples with the spread texture present a linear shaped true stress–strain flow curve. A “quasi horizontal step” appears on the stress–strain curves at the high strain rates, related mainly to {10-12} tension twinning that becomes an important deformation mode of grains. It was believed that the difference of stress–strain responses between the two kinds of tensile samples results from the difference of the slip modes, the contribution of the slips to plastic strain decreases with the increment of strain rate.
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